Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-kappa B. K Natarajan, S Singh, TR Burke Jr, D Grunberger, BB Aggarwal Proceedings of the National Academy of Sciences 93 (17), 9090-9095, 1996 | 1421 | 1996 |
Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling M Baba, SB Hong, N Sharma, MB Warren, ML Nickerson, A Iwamatsu, ... Proceedings of the National Academy of Sciences 103 (42), 15552-15557, 2006 | 546 | 2006 |
Coumarin-based inhibitors of HIV integrase H Zhao, N Neamati, H Hong, A Mazumder, S Wang, S Sunder, GWA Milne, ... Journal of medicinal chemistry 40 (2), 242-249, 1997 | 418 | 1997 |
Potent inhibition of insulin receptor dephosphorylation by a hexamer peptide containing the phosphotyrosyl mimetic F2Pmp TR Burke, HK Kole, PP Roller Biochemical and biophysical research communications 204 (1), 129-134, 1994 | 317 | 1994 |
Syp (SH-PTP2) is a positive mediator of growth factor-stimulated mitogenic signal transduction. S Xiao, DW Rose, T Sasaoka, H Maegawa, TR Burke Jr, PP Roller, ... Journal of Biological Chemistry 269 (33), 21244-21248, 1994 | 301 | 1994 |
Retroviral DNA integration: reaction pathway and critical intermediates M Li, M Mizuuchi, TR Burke Jr, R Craigie The EMBO journal 25 (6), 1295-1304, 2006 | 283 | 2006 |
Grb2 signaling in cell motility and cancer A Giubellino, TR Burke, DP Bottaro Expert opinion on therapeutic targets 12 (8), 1021-1033, 2008 | 282 | 2008 |
Hydroxylated aromatic inhibitors of HIV-1 integrase TRJ Burke, M Fesen, A Mazumder, J Yung, J Wang, AM Carothers, ... Journal of Medicinal Chemistry 38 (21), 4171-4178, 1995 | 273 | 1995 |
Structure activity of 3-aryl-1, 3-diketo-containing compounds as HIV-1 integrase inhibitors GCG Pais, X Zhang, C Marchand, N Neamati, K Cowansage, ... Journal of medicinal chemistry 45 (15), 3184-3194, 2002 | 268 | 2002 |
Protein–tyrosine phosphatases: structure, mechanism, and inhibitor discovery TR Burke Jr, ZY Zhang Peptide Science 47 (3), 225-241, 1998 | 250 | 1998 |
Nonhydrolyzable phosphotyrosyl mimetics for the preparation of phosphatase-resistant SH2 domain inhibitors TRJ Burke, MS Smyth, A Otaka, M Nomizu, PP Roller, G Wolf, R Case, ... Biochemistry 33 (21), 6490-6494, 1994 | 244 | 1994 |
Chicoric acid analogues as HIV-1 integrase inhibitors Z Lin, N Neamati, H Zhao, Y Kiryu, JA Turpin, C Aberham, K Strebel, ... Journal of medicinal chemistry 42 (8), 1401-1414, 1999 | 229 | 1999 |
Caffeic acid phenethyl ester induces leukocyte apoptosis, modulates nuclear factor-kappa B and suppresses acute inflammation Z Orban, N Mitsiades, TR Burke Jr, M Tsokos, GP Chrousos Neuroimmunomodulation 7 (2), 99-105, 1999 | 214 | 1999 |
Preparation of fluoro-and hydroxy-4-(phosphonomethyl)-D, L-phenylalanine suitably protected for solid-phase synthesis of peptides containing hydrolytically stable analogs of O … TR Burke Jr, MS Smyth, M Nomizu, A Otaka, PR Roller The Journal of Organic Chemistry 58 (6), 1336-1340, 1993 | 201 | 1993 |
Antiretroviral agents as inhibitors of both human immunodeficiency virus type 1 integrase and protease A Mazumder, S Wang, N Neamati, M Nicklaus, S Sunder, J Chen, ... Journal of medicinal chemistry 39 (13), 2472-2481, 1996 | 198 | 1996 |
Structural Determinants for HIV-1 Integrase Inhibition by β-Diketo Acids∗ C Marchand, X Zhang, GCG Pais, K Cowansage, N Neamati, TR Burke, ... Journal of Biological Chemistry 277 (15), 12596-12603, 2002 | 197 | 2002 |
Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1 SM Yun, T Moulaei, D Lim, JK Bang, JE Park, SR Shenoy, FA Liu, ... Nature structural & molecular biology 16 (8), 876-882, 2009 | 195 | 2009 |
Protein-tyrosine kinase inhibitors TR Burke Drugs Future 17, 119-131, 1992 | 192 | 1992 |
Irreversible ligands with high selectivity toward δ and μ opiate receptors KC Rice, AE Jacobson, TR Burke Jr, BS Bajwa, RA Streaty, WA Klee Science 220 (4594), 314-316, 1983 | 183 | 1983 |
Metal-dependent inhibition of HIV-1 integrase by β-diketo acids and resistance of the soluble double-mutant (F185K/C280S) C Marchand, AA Johnson, RG Karki, GCG Pais, X Zhang, K Cowansage, ... Molecular pharmacology 64 (3), 600-609, 2003 | 182 | 2003 |