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Hyung Joo Lee
Hyung Joo Lee
Senior Scientist, Bioinformatician, AstraZeneca
Bestätigte E-Mail-Adresse bei astrazeneca.com
Titel
Zitiert von
Zitiert von
Jahr
Targeted genome editing in human cells with zinc finger nucleases constructed via modular assembly
HJ Kim, HJ Lee, H Kim, SW Cho, JS Kim
Genome research 19 (7), 1279-1288, 2009
5862009
Targeted chromosomal deletions in human cells using zinc finger nucleases
HJ Lee, E Kim, JS Kim
Genome research 20 (1), 81-89, 2010
3802010
A genomic and epigenomic atlas of prostate cancer in Asian populations
J Li, C Xu, HJ Lee, S Ren, X Zi, Z Zhang, H Wang, Y Yu, C Yang, X Gao, ...
Nature 580 (7801), 93-99, 2020
2762020
DNA hypomethylation within specific transposable element families associates with tissue-specific enhancer landscape
M Xie, C Hong, B Zhang, RF Lowdon, X Xing, D Li, X Zhou, HJ Lee, ...
Nature genetics 45 (7), 836-841, 2013
2562013
Targeted chromosomal duplications and inversions in the human genome using zinc finger nucleases
HJ Lee, J Kweon, E Kim, S Kim, JS Kim
Genome research 22 (3), 539-548, 2012
2332012
Functional DNA methylation differences between tissues, cell types, and across individuals discovered using the M&M algorithm
B Zhang, Y Zhou, N Lin, RF Lowdon, C Hong, RP Nagarajan, JB Cheng, ...
Genome research 23 (9), 1522-1540, 2013
2232013
MicroRNAs induce a permissive chromatin environment that enables neuronal subtype-specific reprogramming of adult human fibroblasts
DG Abernathy, WK Kim, MJ McCoy, AM Lake, R Ouwenga, SW Lee, ...
Cell stem cell 21 (3), 332-348. e9, 2017
1412017
Genome editing with modularly assembled zinc-finger nucleases
JS Kim, HJ Lee, D Carroll
Nature Methods 7 (2), 91-91, 2010
1362010
Tissue-specific DNA methylation is conserved across human, mouse, and rat, and driven by primary sequence conservation
J Zhou, RL Sears, X Xing, B Zhang, D Li, NB Rockweiler, HS Jang, ...
BMC genomics 18, 1-17, 2017
1152017
A map of cis-regulatory elements and 3D genome structures in zebrafish
H Yang, Y Luan, T Liu, HJ Lee, L Fang, Y Wang, X Wang, B Zhang, Q Jin, ...
Nature 588 (7837), 337-343, 2020
1122020
Developmental enhancers revealed by extensive DNA methylome maps of zebrafish early embryos
HJ Lee, RF Lowdon, B Maricque, B Zhang, M Stevens, D Li, SL Johnson, ...
Nature communications 6 (1), 6315, 2015
902015
Long-term in vitro expansion of epithelial stem cells enabled by pharmacological inhibition of PAK1-ROCK-myosin II and TGF-β signaling
C Zhang, HJ Lee, A Shrivastava, R Wang, TJ McQuiston, SS Challberg, ...
Cell reports 25 (3), 598-610. e5, 2018
782018
Cellular diversity of the regenerating caudal fin
Y Hou, HJ Lee, Y Chen, J Ge, FOI Osman, AR McAdow, MH Mokalled, ...
Science advances 6 (33), eaba2084, 2020
592020
Regenerating zebrafish fin epigenome is characterized by stable lineage-specific DNA methylation and dynamic chromatin accessibility
HJ Lee, Y Hou, Y Chen, ZZ Dailey, A Riddihough, HS Jang, T Wang, ...
Genome biology 21, 1-17, 2020
582020
CRISPRi screens reveal a DNA methylation-mediated 3D genome dependent causal mechanism in prostate cancer
M Ahmed, F Soares, JH Xia, Y Yang, J Li, H Guo, P Su, Y Tian, HJ Lee, ...
Nature communications 12 (1), 1781, 2021
432021
Uropathogenic Escherichia coli infection-induced epithelial trained immunity impacts urinary tract disease outcome
SK Russell, JK Harrison, BS Olson, HJ Lee, VP O’Brien, X Xing, J Livny, ...
Nature microbiology 8 (5), 875-888, 2023
372023
Targeted genomic rearrangements using site-specific nucleases
JS Kim, HJ Lee, EJ Kim
302010
Single-cell transcriptional regulation and genetic evolution of neuroendocrine prostate cancer
Z Wang, T Wang, D Hong, B Dong, Y Wang, H Huang, W Zhang, B Lian, ...
Iscience 25 (7), 2022
292022
Whole-genome profiling of DNA methylation and hydroxymethylation identifies distinct regulatory programs among innate lymphocytes
V Peng, X Xing, JK Bando, T Trsan, B Di Luccia, PL Collins, D Li, ...
Nature immunology 23 (4), 619-631, 2022
202022
Epigenomic analysis reveals prevalent contribution of transposable elements to cis-regulatory elements, tissue-specific expression, and alternative promoters in zebrafish
HJ Lee, Y Hou, JH Maeng, NM Shah, Y Chen, HA Lawson, H Yang, F Yue, ...
Genome research 32 (7), 1424-1436, 2022
172022
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