| MYC drives progression of small cell lung cancer to a variant neuroendocrine subtype with vulnerability to aurora kinase inhibition G Mollaoglu, MR Guthrie, S Böhm, J Brägelmann, I Can, PM Ballieu, ... Cancer cell 31 (2), 270-285, 2017 | 534 | 2017 |
| MYC drives temporal evolution of small cell lung cancer subtypes by reprogramming neuroendocrine fate AS Ireland, AM Micinski, DW Kastner, B Guo, SJ Wait, KB Spainhower, ... Cancer cell 38 (1), 60-78. e12, 2020 | 380 | 2020 |
| Inosine monophosphate dehydrogenase dependence in a subset of small cell lung cancers F Huang, M Ni, MD Chalishazar, KE Huffman, J Kim, L Cai, X Shi, F Cai, ... Cell metabolism 28 (3), 369-382. e5, 2018 | 185 | 2018 |
| MYC-driven small-cell lung cancer is metabolically distinct and vulnerable to arginine depletion MD Chalishazar, SJ Wait, F Huang, AS Ireland, A Mukhopadhyay, Y Lee, ... Clinical Cancer Research 25 (16), 5107-5121, 2019 | 173 | 2019 |
| Protein expression of TTF1 and cMYC define distinct molecular subgroups of small cell lung cancer with unique vulnerabilities to aurora kinase inhibition, DLL3 targeting, and … RJ Cardnell, L Li, T Sen, R Bara, P Tong, J Fujimoto, AS Ireland, ... Oncotarget 8 (43), 73419, 2017 | 92 | 2017 |
| MYC paralog-dependent apoptotic priming orchestrates a spectrum of vulnerabilities in small cell lung cancer MA Dammert, J Brägelmann, RR Olsen, S Böhm, N Monhasery, ... Nature communications 10 (1), 3485, 2019 | 82 | 2019 |
| Killing SCLC: insights into how to target a shapeshifting tumor KD Sutherland, AS Ireland, TG Oliver Genes & Development 36 (5-6), 241-258, 2022 | 54 | 2022 |
| ASCL1 represses a SOX9+ neural crest stem-like state in small cell lung cancer RR Olsen, AS Ireland, DW Kastner, SM Groves, KB Spainhower, K Pozo, ... Genes & Development 35 (11-12), 847-869, 2021 | 54 | 2021 |
| Guanosine triphosphate links MYC-dependent metabolic and ribosome programs in small-cell lung cancer F Huang, KE Huffman, Z Wang, X Wang, K Li, F Cai, C Yang, L Cai, ... The Journal of clinical investigation 131 (1), 2021 | 52 | 2021 |
| Archetype tasks link intratumoral heterogeneity to plasticity and cancer hallmarks in small cell lung cancer SM Groves, GV Ildefonso, CO McAtee, PMM Ozawa, AS Ireland, ... Cell systems 13 (9), 690-710. e17, 2022 | 37 | 2022 |
| Neutrophils create an ImpeNETrable shield between tumor and cytotoxic immune cells AS Ireland, TG Oliver Immunity 52 (5), 729-731, 2020 | 37 | 2020 |
| Cancer hallmarks define a continuum of plastic cell states between small cell lung cancer archetypes SM Groves, A Ireland, Q Liu, AJ Simmons, K Lau, WT Iams, D Tyson, ... BioRxiv, 2021.01. 22.427865, 2021 | 17 | 2021 |
| Olfactory neuroblastoma mimics molecular heterogeneity and lineage trajectories of small-cell lung cancer JB Finlay, AS Ireland, SB Hawgood, T Reyes, T Ko, RR Olsen, ... Cancer Cell, 2024 | 5 | 2024 |
| Kinase Suppressor of Ras 2 promotes self-renewal and clonogenicity of small-cell lung carcinoma DH Huisman, D Chatterjee, RA Svoboda, HM Vieira, AS Ireland, S Skupa, ... BioRxiv, 2022.02. 11.480157, 2022 | 1 | 2022 |
| ASCL1 represses a latent osteogenic program in small cell lung Cancer in multiple cells of origin RR Olsen, DW Kastner, AS Ireland, SM Groves, K Pozo, CP Whitney, ... bioRxiv, 2020.11. 11.362632, 2020 | 1 | 2020 |
| IA21 ASCL1 represses a latent osteogenic program in small-cell lung cancer arising from multiple cells of origin RR Olsen, DW Kastner, AS Ireland, K Pozo, CP Whitney, MR Guthrie, ... Journal of Thoracic Oncology 15 (2), S7, 2020 | 1 | 2020 |
| Basal cell of origin resolves neuroendocrine-tuft lineage plasticity in cancer AS Ireland, SB Hawgood, DA Xie, MW Barbier, S Lucas-Randolph, ... bioRxiv, 2024.11. 13.623500, 2024 | | 2024 |
| Kinase Suppressor of Ras 2 regulates small-cell lung carcinoma tumor propagating cells DH Huisman, DE Frodyma, RA Svoboda, HM Vieira, D Chatterjee, ... | | 2022 |
| Abstract PO-120: MYC drives temporal evolution of small cell lung cancer subtypes by reprogramming neuroendocrine fate AS Ireland, AM Micinski, DW Kastner, B Guo, SJ Wait, KB Spainhower, ... Cancer Research 80 (21_Supplement), PO-120-PO-120, 2020 | | 2020 |
| Abstract IA27: MYC drives molecular and therapeutically distinct subtype of SCLC G Mollaoglu, MR Guthrie, S Bohm, J Bragelmann, MD Chalishazar, ... Clinical Cancer Research 24 (17_Supplement), IA27-IA27, 2018 | | 2018 |
