Heparin and cancer revisited: mechanistic connections involving platelets, P-selectin, carcinoma mucins, and tumor metastasis L Borsig, R Wong, J Feramisco, DR Nadeau, NM Varki, A Varki Proceedings of the National Academy of Sciences 98 (6), 3352-3357, 2001 | 877 | 2001 |
P-selectin deficiency attenuates tumor growth and metastasis YJ Kim, L Borsig, NM Varki, A Varki Proceedings of the National Academy of Sciences 95 (16), 9325-9330, 1998 | 622 | 1998 |
Cancer cell adhesion and metastasis: selectins, integrins, and the inhibitory potential of heparins G Bendas, L Borsig International journal of cell biology 2012 (1), 676731, 2012 | 621 | 2012 |
Selectins promote tumor metastasis H Läubli, L Borsig Seminars in cancer biology 20 (3), 169-177, 2010 | 562 | 2010 |
Synergistic effects of L-and P-selectin in facilitating tumor metastasis can involve non-mucin ligands and implicate leukocytes as enhancers of metastasis L Borsig, R Wong, RO Hynes, NM Varki, A Varki Proceedings of the National Academy of Sciences 99 (4), 2193-2198, 2002 | 543 | 2002 |
Altered tumor-cell glycosylation promotes metastasis I Häuselmann, L Borsig Frontiers in oncology 4, 28, 2014 | 432 | 2014 |
Selectin-mucin interactions as a probable molecular explanation for the association of Trousseau syndrome with mucinous adenocarcinomas M Wahrenbrock, L Borsig, D Le, N Varki, A Varki The Journal of clinical investigation 112 (6), 853-862, 2003 | 398 | 2003 |
Endothelial CCR2 signaling induced by colon carcinoma cells enables extravasation via the JAK2-Stat5 and p38MAPK pathway MJ Wolf, A Hoos, J Bauer, S Boettcher, M Knust, A Weber, N Simonavicius, ... Cancer cell 22 (1), 91-105, 2012 | 327 | 2012 |
P-selectin mediates the adhesion of sickle erythrocytes to the endothelium NM Matsui, L Borsig, SD Rosen, M Yaghmai, A Varki, SH Embury Blood, The Journal of the American Society of Hematology 98 (6), 1955-1962, 2001 | 316 | 2001 |
Inflammatory chemokines and metastasis—tracing the accessory L Borsig, MJ Wolf, M Roblek, A Lorentzen, M Heikenwalder Oncogene 33 (25), 3217-3224, 2014 | 257 | 2014 |
Gut microbiota modulate T cell trafficking into human colorectal cancer E Cremonesi, V Governa, JFG Garzon, V Mele, F Amicarella, MG Muraro, ... Gut 67 (11), 1984-1994, 2018 | 251 | 2018 |
The role of platelet activation in tumor metastasis L Borsig Expert review of anticancer therapy 8 (8), 1247-1255, 2008 | 248 | 2008 |
Distinct selectin ligands on colon carcinoma mucins can mediate pathological interactions among platelets, leukocytes, and endothelium YJ Kim, L Borsig, HL Han, NM Varki, A Varki The American journal of pathology 155 (2), 461-472, 1999 | 248 | 1999 |
Selectin blocking activity of a fucosylated chondroitin sulfate glycosaminoglycan from sea cucumber: Effect on tumor metastasis and neutrophil recruitment L Borsig, L Wang, MCM Cavalcante, L Cardilo-Reis, PL Ferreira, ... Journal of Biological Chemistry 282 (20), 14984-14991, 2007 | 237 | 2007 |
Altered cell adhesion and glycosylation promote cancer immune suppression and metastasis H Läubli, L Borsig Frontiers in immunology 10, 2120, 2019 | 231 | 2019 |
L-Selectin Facilitation of Metastasis Involves Temporal Induction of Fut7-Dependent Ligands at Sites of Tumor Cell Arrest H Läubli, JL Stevenson, A Varki, NM Varki, L Borsig Cancer research 66 (3), 1536-1542, 2006 | 220 | 2006 |
CCL2-CCR2 signaling in disease pathogenesis T O’Connor, L Borsig, M Heikenwalder Endocrine, Metabolic & Immune Disorders-Drug Targets (Formerly Current Drug …, 2015 | 185 | 2015 |
Selectin-mediated activation of endothelial cells induces expression of CCL5 and promotes metastasis through recruitment of monocytes H Läubli, KS Spanaus, L Borsig Blood, The Journal of the American Society of Hematology 114 (20), 4583-4591, 2009 | 174 | 2009 |
Selectins in cancer immunity L Borsig Glycobiology 28 (9), 648-655, 2018 | 172 | 2018 |
Heparin attenuates metastasis mainly due to inhibition of P-and L-selectin, but non-anticoagulant heparins can have additional effects JL Stevenson, A Varki, L Borsig Thrombosis Research 120, S107-S111, 2007 | 170 | 2007 |