| Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Aβ and synaptic dysfunction S Oddo, A Caccamo, JD Shepherd, MP Murphy, TE Golde, R Kayed, ... Neuron 39 (3), 409-421, 2003 | 5077 | 2003 |
| An Increased Percentage of Long Amyloid β Protein Secreted by Familial Amyloid β Protein Precursor (βApp717) Mutants N Suzuki, TT Cheung, XD Cai, A Odaka, L Otvos Jr, C Eckman, TE Golde, ... Science 264 (5163), 1336-1340, 1994 | 2266 | 1994 |
| Production of the Alzheimer amyloid β protein by normal proteolytic processing M Shoji, TE Golde, J Ghiso, TT Cheung, S Estus, LM Shaffer, XD Cai, ... Science 258 (5079), 126-129, 1992 | 1979 | 1992 |
| A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity S Weggen, JL Eriksen, P Das, SA Sagi, R Wang, CU Pietrzik, KA Findlay, ... Nature 414 (6860), 212-216, 2001 | 1877 | 2001 |
| Release of excess amyloid β protein from a mutant amyloid β protein precursor XD Cai, TE Golde, SG Younkin Science 259 (5094), 514-516, 1993 | 1490 | 1993 |
| γ-Secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase CY Ni, MP Murphy, TE Golde, G Carpenter Science 294 (5549), 2179-2181, 2001 | 1052 | 2001 |
| Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease R Sims, SJ Van Der Lee, AC Naj, C Bellenguez, N Badarinarayan, ... Nature genetics 49 (9), 1373-1384, 2017 | 990 | 2017 |
| The secretases: enzymes with therapeutic potential in Alzheimer disease B De Strooper, R Vassar, T Golde Nature reviews neurology 6 (2), 99-107, 2010 | 982 | 2010 |
| Processing of the amyloid protein precursor to potentially amyloidogenic derivatives TE Golde, S Estus, LH Younkin, DJ Selkoe, SG Younkin Science 255 (5045), 728-730, 1992 | 966 | 1992 |
| NSAIDs and enantiomers of flurbiprofen target γ-secretase and lower Aβ42 in vivo JL Eriksen, SA Sagi, TE Smith, S Weggen, P Das, DC McLendon, ... The Journal of clinical investigation 112 (3), 440-449, 2003 | 902 | 2003 |
| Large-scale proteomic analysis of Alzheimer’s disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation ECB Johnson, EB Dammer, DM Duong, L Ping, M Zhou, L Yin, ... Nature medicine 26 (5), 769-780, 2020 | 789 | 2020 |
| Aβ42 is essential for parenchymal and vascular amyloid deposition in mice E McGowan, F Pickford, J Kim, L Onstead, J Eriksen, C Yu, L Skipper, ... Neuron 47 (2), 191-199, 2005 | 731 | 2005 |
| Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity YJ Zhang, YF Xu, C Cook, TF Gendron, P Roettges, CD Link, WL Lin, ... Proceedings of the National Academy of Sciences 106 (18), 7607-7612, 2009 | 700 | 2009 |
| Animal models of neurodegenerative diseases TM Dawson, TE Golde, C Lagier-Tourenne Nature neuroscience 21 (10), 1370-1379, 2018 | 575 | 2018 |
| Cholesterol-dependent γ-secretase activity in buoyant cholesterol-rich membrane microdomains S Wahrle, P Das, AC Nyborg, C McLendon, M Shoji, T Kawarabayashi, ... Neurobiology of disease 9 (1), 11-23, 2002 | 550 | 2002 |
| Expression of β amyloid protein precursor mRNAs: recognition of a novel alternatively spliced form and quantitation in Alzheimer's disease using PCR TE Golde, S Estus, M Usiak, LH Younkin, SG Younkin Neuron 4 (2), 253-267, 1990 | 547 | 1990 |
| Potentially amyloidogenic, carboxyl-terminal derivatives of the amyloid protein precursor S Estus, TE Golde, T Kunishita, D Blades, D Lowery, M Eisen, M Usiak, ... Science 255 (5045), 726-728, 1992 | 536 | 1992 |
| Targeting Notch to target cancer stem cells A Pannuti, K Foreman, P Rizzo, C Osipo, T Golde, B Osborne, L Miele Clinical cancer research 16 (12), 3141-3152, 2010 | 535 | 2010 |
| Anti-Aβ therapeutics in Alzheimer's disease: the need for a paradigm shift TE Golde, LS Schneider, EH Koo Neuron 69 (2), 203-213, 2011 | 491 | 2011 |
| Rational targeting of Notch signaling in cancer P Rizzo, C Osipo, K Foreman, T Golde, B Osborne, L Miele Oncogene 27 (38), 5124-5131, 2008 | 490 | 2008 |
