| Converging blockchain and next-generation artificial intelligence technologies to decentralize and accelerate biomedical research and healthcare P Mamoshina, L Ojomoko, Y Yanovich, A Ostrovski, A Botezatu, ... Oncotarget 9 (5), 5665, 2017 | 505 | 2017 |
| Patient-derived xenografts effectively capture responses to oncology therapy in a heterogeneous cohort of patients with solid tumors E Izumchenko, K Paz, D Ciznadija, I Sloma, A Katz, D Vasquez-Dunddel, ... Annals of Oncology 28 (10), 2595-2605, 2017 | 322 | 2017 |
| Bifunctional immune checkpoint-targeted antibody-ligand traps that simultaneously disable TGFβ enhance the efficacy of cancer immunotherapy R Ravi, KA Noonan, V Pham, R Bedi, A Zhavoronkov, IV Ozerov, ... Nature communications 9 (1), 741, 2018 | 314 | 2018 |
| In silico Pathway Activation Network Decomposition Analysis (iPANDA) as a method for biomarker development IV Ozerov, KV Lezhnina, E Izumchenko, AV Artemov, S Medintsev, ... Nature communications 7 (1), 13427, 2016 | 158 | 2016 |
| Targeted sequencing reveals clonal genetic changes in the progression of early lung neoplasms and paired circulating DNA E Izumchenko, X Chang, M Brait, E Fertig, LT Kagohara, A Bedi, ... Nature communications 6 (1), 8258, 2015 | 157 | 2015 |
| NEDD9 promotes oncogenic signaling in mammary tumor development E Izumchenko, MK Singh, OV Plotnikova, N Tikhmyanova, JL Little, ... Cancer research 69 (18), 7198-7206, 2009 | 155 | 2009 |
| The TGFβ–miR200–MIG6 pathway orchestrates the EMT-associated kinase switch that induces resistance to EGFR inhibitors E Izumchenko, X Chang, C Michailidi, L Kagohara, R Ravi, K Paz, M Brait, ... Cancer research 74 (14), 3995-4005, 2014 | 154 | 2014 |
| Cooperative antitumor effects of vitamin D3 derivatives and rosemary preparations in a mouse model of myeloid leukemia H Sharabani, E Izumchenko, Q Wang, R Kreinin, M Steiner, Z Barvish, ... International Journal of Cancer 118 (12), 3012-3021, 2006 | 104 | 2006 |
| Vive la radiorésistance!: converging research in radiobiology and biogerontology to enhance human radioresistance for deep space exploration and colonization F Cortese, D Klokov, A Osipov, J Stefaniak, A Moskalev, J Schastnaya, ... Oncotarget 9 (18), 14692, 2018 | 101 | 2018 |
| Notch1 mutations are drivers of oral tumorigenesis E Izumchenko, K Sun, S Jones, M Brait, N Agrawal, W Koch, CL McCord, ... Cancer prevention research 8 (4), 277-286, 2015 | 93 | 2015 |
| Immune profiles in primary squamous cell carcinoma of the head and neck V Saloura, E Izumchenko, Z Zuo, R Bao, M Korzinkin, I Ozerov, ... Oral Oncology 96, 77-88, 2019 | 76 | 2019 |
| OrganoID: A versatile deep learning platform for tracking and analysis of single-organoid dynamics JM Matthews, B Schuster, SS Kashaf, P Liu, R Ben-Yishay, ... PLoS computational biology 18 (11), e1010584, 2022 | 74 | 2022 |
| SMAD4 loss is associated with cetuximab resistance and induction of MAPK/JNK activation in head and neck cancer cells H Ozawa, RS Ranaweera, E Izumchenko, E Makarev, A Zhavoronkov, ... Clinical Cancer Research 23 (17), 5162-5175, 2017 | 73 | 2017 |
| Adenoid cystic carcinoma: emerging role of translocations and gene fusions PT Wysocki, E Izumchenko, J Meir, PK Ha, D Sidransky, M Brait Oncotarget 7 (40), 66239, 2016 | 73 | 2016 |
| A small-molecule TNIK inhibitor targets fibrosis in preclinical and clinical models F Ren, A Aliper, J Chen, H Zhao, S Rao, C Kuppe, IV Ozerov, M Zhang, ... Nature Biotechnology, 1-13, 2024 | 71 | 2024 |
| Patient‐derived xenografts as tools in pharmaceutical development E Izumchenko, J Meir, A Bedi, PT Wysocki, MO Hoque, D Sidransky Clinical Pharmacology & Therapeutics 99 (6), 612-621, 2016 | 70 | 2016 |
| Identification of therapeutic targets for amyotrophic lateral sclerosis using PandaOmics–an AI-enabled biological target discovery platform FW Pun, BHM Liu, X Long, HW Leung, GHD Leung, QT Mewborne, J Gao, ... Frontiers in aging neuroscience 14, 914017, 2022 | 69 | 2022 |
| Integrated analysis of whole-genome ChIP-Seq and RNA-Seq data of primary head and neck tumor samples associates HPV integration sites with open chromatin marks DZ Kelley, EL Flam, E Izumchenko, LV Danilova, HA Wulf, T Guo, ... Cancer research 77 (23), 6538-6550, 2017 | 64 | 2017 |
| Involvement of epigenetics and EMT-related miRNA in arsenic-induced neoplastic transformation and their potential clinical use C Michailidi, M Hayashi, S Datta, T Sen, K Zenner, O Oladeru, M Brait, ... Cancer prevention research 8 (3), 208-221, 2015 | 63 | 2015 |
| Hallmarks of aging-based dual-purpose disease and age-associated targets predicted using PandaOmics AI-powered discovery engine FW Pun, GHD Leung, HW Leung, BHM Liu, X Long, IV Ozerov, J Wang, ... Aging (Albany NY) 14 (6), 2475, 2022 | 62 | 2022 |
David SidranskyProfessor Johns Hopkins UniversityBestätigte E-Mail-Adresse bei jhmi.edu