The code and beyond: transcription regulation by the RNA polymerase II carboxy-terminal domain KM Harlen, LS Churchman Nature reviews Molecular cell biology 18 (4), 263-273, 2017 | 520 | 2017 |
The ferritin superfamily: Supramolecular templates for materials synthesis M Uchida, S Kang, C Reichhardt, K Harlen, T Douglas Biochimica et Biophysica Acta (BBA)-General Subjects 1800 (8), 834-845, 2010 | 312 | 2010 |
Comprehensive RNA polymerase II interactomes reveal distinct and varied roles for each phospho-CTD residue KM Harlen, KL Trotta, EE Smith, MM Mosaheb, SM Fuchs, LS Churchman Cell reports 15 (10), 2147-2158, 2016 | 184 | 2016 |
Subgenic Pol II interactomes identify region‐specific transcription elongation regulators KM Harlen, LS Churchman Molecular Systems Biology 13 (1), 900, 2017 | 49 | 2017 |
Mechanism of membrane permeation induced by synthetic β-hairpin peptides K Gupta, H Jang, K Harlen, A Puri, R Nussinov, JP Schneider, ... Biophysical journal 105 (9), 2093-2103, 2013 | 45 | 2013 |
Cell-cycle modulation of transcription termination factor Sen1 HE Mischo, Y Chun, KM Harlen, BM Smalec, S Dhir, LS Churchman, ... Molecular Cell 70 (2), 312-326. e7, 2018 | 29 | 2018 |
Transcription elongation is finely tuned by dozens of regulatory factors M Couvillion, KM Harlen, KC Lachance, KL Trotta, E Smith, C Brion, ... Elife 11, e78944, 2022 | 22 | 2022 |
Live-cell assays for cell stress responses reveal new patterns of cell signaling caused by mutations in rhodopsin, α-synuclein and TDP-43 KM Harlen, EC Roush, JE Clayton, S Martinka, TE Hughes Frontiers in Cellular Neuroscience 13, 535, 2019 | 10 | 2019 |
Neurodegenerative disease and cAMP signaling dynamics E Roush, K Harlen, M Hendrickson, TE Hughes Biophysical Journal 118 (3), 456a, 2020 | 3 | 2020 |
Interactome Dynamics of the Transcription Elongation Complex Revealed by Quantitative Proteomics K Harlen, S Churchman The FASEB Journal 29, 562.3, 2015 | 2 | 2015 |
Dynamics of transcription elongation are finely tuned by dozens of regulatory factors M Couvillion, KM Harlen, KC Lachance, KL Trotta, E Smith, C Brion, ... bioRxiv, 2021.08. 15.456358, 2021 | 1 | 2021 |
Biosensors for measuring cell signaling in stressed and healthy cells T Hughes, K Harlen US Patent App. 16/629,485, 2020 | | 2020 |
Live-cell biosensors reveal novel insight into neurotoxic and cardiotoxic compound mediated cellular stress response K Harlen, T Hughes, C Fleming, G Luerman Journal of Pharmacological and Toxicological Methods 99, 106595, 2019 | | 2019 |
Thapsigargin-induced cellular stress response and inhibition of Gq-dependent calcium signaling. JE Clayton, KM Harlen, T Hughes MOLECULAR BIOLOGY OF THE CELL 29 (26), 2018 | | 2018 |
Cell Stress Biosensors for Rapid, Live-Cell Detection of Neurotoxic and Cardiotoxic Compounds in iPSC-Derived Neurons and Cardiomyocytes. KM Harlen, T Hughes, AM Quinn MOLECULAR BIOLOGY OF THE CELL 29 (26), 2018 | | 2018 |
Watching Biased Agonism at GPCRs in real time. PH Tewson, AM Quinn, SA Martinka, KM Harlen, TE Hughes MOLECULAR BIOLOGY OF THE CELL 29 (26), 2018 | | 2018 |
A Genetically‐Encoded Fluorescent Assay to Detect Drug Toxicity and Genetic Stress in Living Cells KM Harlen, T Hughes, AM Quinn The FASEB Journal 32, lb639-lb639, 2018 | | 2018 |
GENIe: A bright new genetically‐encoded fluorescent biosensor for monitoring cGMP KM Harlen, P Tewson, S Martinka, T Hughes, AM Quinn The FASEB Journal 32, lb638-lb638, 2018 | | 2018 |
New Fluorescent Tools to Identify Stressed Cells and Interrogate Second Messenger Signaling in Neurodegeneration T Hughes, K Harlen Biophysical Journal 114 (3), 287a, 2018 | | 2018 |
The Regulation of RNA Polymerase II Transcription and Co-Transcriptional Processes KM Harlen | | 2016 |