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Thomas R. Cox
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Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer
TR Cox, JT Erler
Disease models & mechanisms 4 (2), 165-178, 2011
18872011
Pre-metastatic niches: organ-specific homes for metastases
H Peinado, H Zhang, IR Matei, B Costa-Silva, A Hoshino, G Rodrigues, ...
Nature Reviews Cancer 17 (5), 302-317, 2017
18112017
Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche
JT Erler, KL Bennewith, TR Cox, G Lang, D Bird, A Koong, QT Le, ...
Cancer cell 15 (1), 35-44, 2009
14352009
The matrix in cancer
TR Cox
Nature Reviews Cancer 21 (4), 217-238, 2021
7342021
The rationale for targeting the LOX family in cancer
HE Barker, TR Cox, JT Erler
Nature Reviews Cancer 12 (8), 540-552, 2012
6472012
LOX-mediated collagen crosslinking is responsible for fibrosis-enhanced metastasis
TR Cox, D Bird, AM Baker, HE Barker, MWY Ho, G Lang, JT Erler
Cancer research 73 (6), 1721-1732, 2013
6182013
Targeting stromal remodeling and cancer stem cell plasticity overcomes chemoresistance in triple negative breast cancer
AS Cazet, MN Hui, BL Elsworth, SZ Wu, D Roden, CL Chan, JN Skhinas, ...
Nature communications 9 (1), 2897, 2018
4002018
Lysyl oxidase enzymatic function increases stiffness to drive colorectal cancer progression through FAK
AM Baker, D Bird, G Lang, TR Cox, JT Erler
Oncogene 32 (14), 1863-1868, 2013
3672013
LOXL2-mediated matrix remodeling in metastasis and mammary gland involution
HE Barker, J Chang, TR Cox, G Lang, D Bird, M Nicolau, HR Evans, ...
Cancer research 71 (5), 1561-1572, 2011
3362011
Stromal cell diversity associated with immune evasion in human triple‐negative breast cancer
SZ Wu, DL Roden, C Wang, H Holliday, K Harvey, AS Cazet, KJ Murphy, ...
The EMBO journal 39 (19), e104063, 2020
3332020
CAF subpopulations: a new reservoir of stromal targets in pancreatic cancer
BA Pereira, C Vennin, M Papanicolaou, CR Chambers, D Herrmann, ...
Trends in cancer 5 (11), 724-741, 2019
2862019
Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis
C Vennin, VT Chin, SC Warren, MC Lucas, D Herrmann, A Magenau, ...
Science Translational Medicine 9, 2017
2662017
Cancer cells’ ability to mechanically adjust to extracellular matrix stiffness correlates with their invasive potential
L Wullkopf, AKV West, N Leijnse, TR Cox, CD Madsen, LB Oddershede, ...
Molecular biology of the cell 29 (20), 2378-2385, 2018
2572018
Lamin A/C is a risk biomarker in colorectal cancer
ND Willis, TR Cox, SF Rahman-Casans, K Smits, SA Przyborski, ...
PloS one 3 (8), e2988, 2008
2502008
The role of lysyl oxidase in SRC-dependent proliferation and metastasis of colorectal cancer
AM Baker, TR Cox, D Bird, G Lang, GI Murray, XF Sun, SM Southall, ...
Journal of the National Cancer Institute 103 (5), 407-424, 2011
2422011
CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan
C Vennin, P Mélénec, R Rouet, M Nobis, AS Cazet, KJ Murphy, ...
Nature communications 10 (1), 3637, 2019
2382019
Reshaping the tumor stroma for treatment of pancreatic cancer
C Vennin, KJ Murphy, JP Morton, TR Cox, M Pajic, P Timpson
Gastroenterology 154 (4), 820-838, 2018
2122018
The extracellular matrix as a key regulator of intracellular signalling networks
JF Hastings, JN Skhinas, D Fey, DR Croucher, TR Cox
British journal of pharmacology 176 (1), 82-92, 2019
2102019
Molecular pathways: connecting fibrosis and solid tumor metastasis
TR Cox, JT Erler
Clinical Cancer Research 20 (14), 3637-3643, 2014
1882014
ISDoT: in situ decellularization of tissues for high-resolution imaging and proteomic analysis of native extracellular matrix
AE Mayorca-Guiliani, CD Madsen, TR Cox, ER Horton, FA Venning, ...
Nature medicine 23 (7), 890-898, 2017
1862017
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