| C7-Derivatization of C3-Alkylindoles Including Tryptophans and Tryptamines RP Loach, OS Fenton, K Amaike, DS Siegel, E Ozkal, M Movassaghi The Journal of organic chemistry 79 (22), 11254-11263, 2014 | 119 | 2014 |
| Employing Photoredox Catalysis for DNA‐Encoded Chemistry: Decarboxylative Alkylation of α‐Amino Acids DK Kölmel, RP Loach, T Knauber, ME Flanagan ChemMedChem 13 (20), 2159-2165, 2018 | 104 | 2018 |
| Employing Photoredox Catalysis for DNA‐Encoded Chemistry: Decarboxylative Alkylation of α‐Amino Acids DK Kölmel, RP Loach, T Knauber, ME Flanagan ChemMedChem 13 (20), 2159-2165, 2018 | 104 | 2018 |
| General, regiodefined access to alpha-substituted butenolides through metal-halogen exchange of 3-bromo-2-silyloxyfurans. Efficient synthesis of an anti-inflammatory gorgonian … J Boukouvalas, RP Loach The Journal of organic chemistry 73 (20), 8109-8112, 2008 | 92 | 2008 |
| On-DNA decarboxylative arylation: merging photoredox with nickel catalysis in water DK Kölmel, J Meng, MH Tsai, J Que, RP Loach, T Knauber, J Wan, ... ACS Combinatorial Science 21 (8), 588-597, 2019 | 88 | 2019 |
| Concise Total Synthesis of (+)-Asperazine, (+)-Pestalazine A, and (+)-iso-Pestalazine A. Structure Revision of (+)-Pestalazine A RP Loach, OS Fenton, M Movassaghi Journal of the American Chemical Society 138 (3), 1057-1064, 2016 | 66 | 2016 |
| Unified route to asymmetrically substituted butenolide, maleic anhydride, and maleimide constituents of Antrodia camphorata J Boukouvalas, V Albert, RP Loach, R Lafleur-Lambert Tetrahedron 68 (47), 9592-9597, 2012 | 30 | 2012 |
| Oxidative rearrangement of 2-furylcarbamates with dimethyldioxirane: a high-yielding preparation of 5-hydroxypyrrol-2 (5H)-ones J Boukouvalas, RP Loach, E Ouellet Tetrahedron letters 52 (39), 5047-5050, 2011 | 25 | 2011 |
| α-Chiral amines via thermally promoted deaminative addition of alkylpyridinium salts to sulfinimines KM Baker, A Tallon, RP Loach, OP Bercher, MA Perry, MP Watson Organic letters 23 (20), 7735-7739, 2021 | 19 | 2021 |
| Concise total synthesis of (+)-asperazine A and (+)-pestalazine B BM Nelson, RP Loach, S Schiesser, M Movassaghi Organic & biomolecular chemistry 16 (2), 202-207, 2018 | 19 | 2018 |
| Early clinical development of lufotrelvir as a potential therapy for COVID-19 C Allais, D Bernhardson, AR Brown, GM Chinigo, JN Desrosiers, ... Organic Process Research & Development 27 (12), 2223-2239, 2023 | 17 | 2023 |
| Concise Total Synthesis of (−)-Auxofuran by a Click Diels–Alder Strategy J Boukouvalas, RP Loach Organic letters 15 (18), 4912-4914, 2013 | 16 | 2013 |
| Direct C7 Functionalization of Tryptophan. Synthesis of Methyl (S)-2-((tert-Butoxycarbonyl) amino)-3-(7-(4, 4, 5, 5-tetramethyl-1, 3, 2-dioxaborolan-2-yl)-1H-indol-3-yl) propanoate K Amaike, RP Loach, M Movassaghi Organic syntheses; an annual publication of satisfactory methods for the …, 2015 | 15 | 2015 |
| Aminolactone Chiral Modifiers for Heterogeneous Asymmetric Hydrogenation: Corrected Structure of Pantoyl-Naphthylethylamine, in-Situ Hydrogenolysis, and Scanning Tunneling … G Goubert, V Demers-Carpentier, RP Loach, R Lafleur-Lambert, ... ACS Catalysis 3 (12), 2677-2683, 2013 | 14 | 2013 |
| Dimethyldioxirane oxidation of 2-silyloxypyrroles: An efficient regiocontrolled synthesis of 5-hydroxy-3-pyrrolin-2-ones J Boukouvalas, Y Xiao, YX Cheng, RP Loach Synlett 2007 (20), 3198-3200, 2007 | 7 | 2007 |
| Expedient Assembly of Bioactive Maleic Anhydrides Using Click Diels–Alder Chemistry J Boukouvalas, C Thibault, RP Loach Synlett 25 (15), 2139-2142, 2014 | 5 | 2014 |
| Catalytic σ‐Bond Annulation with Ambiphilic Organohalides Enabled by β‐X Elimination HQ Ni, JC Dai, S Yang, RP Loach, MD Chuba, IJ McAlpine, KM Engle Angewandte Chemie International Edition 62 (34), e202306581, 2023 | 4 | 2023 |
| Discovery of PF-07265028, A Selective Small Molecule Inhibitor of Hematopoietic Progenitor Kinase 1 (HPK1) for the Treatment of Cancer RA Gallego, S Cho-Schultz, M Del Bel, AM Dechert-Schmitt, ... Journal of Medicinal Chemistry 67 (24), 22002-22038, 2024 | 2 | 2024 |
| Front Cover: Employing Photoredox Catalysis for DNA‐Encoded Chemistry: Decarboxylative Alkylation of α‐Amino Acids (ChemMedChem 20/2018) DK Kölmel, RP Loach, T Knauber, ME Flanagan ChemMedChem 13 (20), 2132-2132, 2018 | 1 | 2018 |
| Alkyl Sulfonyl Fluorides as Ambiphiles in the Stereoselective, Palladium (II)-Catalyzed Cyclopropanation of Unactivated Alkenes Y Cao, W Rodphon, T Alturaifi, A Lisboa, Z Ren, J Struijs, HQ Ni, ... | | 2024 |
Dr. Thomas KnauberPostdoctoral Fellow, Department of Chemistry, McGill UniversityBestätigte E-Mail-Adresse bei mail.mcgill.ca