DP2 antagonism reduces airway smooth muscle mass in asthma by decreasing eosinophilia and myofibroblast recruitment R Saunders, H Kaul, R Berair, S Gonem, A Singapuri, AJ Sutcliffe, ... Science translational medicine 11 (479), eaao6451, 2019 | 74 | 2019 |
Scaling of an antibody validation procedure enables quantification of antibody performance in major research applications R Ayoubi, J Ryan, MS Biddle, W Alshafie, M Fotouhi, SG Bolivar, ... Elife 12, RP91645, 2023 | 54 | 2023 |
Validation of antibodies for the specific detection of human TRPA1 HS Virk, MZ Rekas, MS Biddle, AKA Wright, J Sousa, CA Weston, ... Scientific reports 9 (1), 18500, 2019 | 28 | 2019 |
YCharOS open antibody characterisation data: Lessons learned and progress made MS Biddle, HS Virk F1000Research 12, 2023 | 24 | 2023 |
Stressed out-The role of oxidative stress in airway smooth muscle dysfunction in asthma and COPD RM Saunders, M Biddle, Y Amrani, CE Brightling Free Radical Biology and Medicine 185, 97-119, 2022 | 24 | 2022 |
Increased β2-adrenoceptor phosphorylation in airway smooth muscle in severe asthma: possible role of mast cell-derived growth factors L Chachi, A Alzahrani, C Koziol-White, M Biddle, R Bagadood, ... Clinical & Experimental Immunology 194 (2), 253-258, 2018 | 24 | 2018 |
A consensus platform for antibody characterization R Ayoubi, J Ryan, SG Bolivar, C Alende, VR Moleon, M Fotouhi, ... | 19 | 2024 |
YCharOS open antibody characterisation data: Lessons learned and progress made. F1000Res. 2023; 12 (12): 1344 MS Biddle, HS Virk Publisher Full Text, 0 | 14 | |
Scaling of an antibody validation procedure enables quantification of antibody performance in major research applications. elife. 2023; 12: 12 R Ayoubi, J Ryan, MS Biddle Publisher Full Text, 0 | 13 | |
TGFβ1 induces resistance of human lung myofibroblasts to cell death via down‐regulation of TRPA1 channels HS Virk, MS Biddle, DT Smallwood, CA Weston, E Castells, VW Bowman, ... British journal of pharmacology 178 (15), 2948-2962, 2021 | 11 | 2021 |
Fevipiprant (QAW039) reduces airway smooth muscle mass in asthma via antagonism of the prostaglandin D2 receptor 2 (DP2) RM Saunders, H Kaul, R Berair, A Singapuri, I Chernyavsky, L Chachi, ... B101. ADVANCES IN ASTHMA, A4677-A4677, 2017 | 9 | 2017 |
The identification of high-performing antibodies for RNA-binding protein FUS for use in Western Blot, immunoprecipitation, and immunofluorescence W Alshalfie, M Biddle, M Fotouhi, R Ayoubi, Z You, K Southern, ... F1000Research 12, 2023 | 6 | 2023 |
Human lung mast cells impair corticosteroid responsiveness in human airway smooth muscle cells A Alzahrani, J Hakeem, M Biddle, F Alhadian, A Hussain, L Khalfaoui, ... Frontiers in Allergy 2, 785100, 2021 | 4 | 2021 |
Improving the integrity and reproducibility of research that uses antibodies: a technical, data sharing, behavioral and policy challenge M Biddle, P Stylianou, M Rekas, A Wright, J Sousa, D Ruddy, MI Stefana, ... Mabs 16 (1), 2323706, 2024 | 3 | 2024 |
Fevipiprant reduces airway smooth muscle mass in asthmatics via PGD2 receptor antagonism R Saunders, H Kaul, R Berair, A Singapuri, I Chernyavsky, L Chachi, ... European Respiratory Journal 50 (suppl 61), 2017 | 2 | 2017 |
A guide to selecting high-performing antibodies for Synaptotagmin-1 (Uniprot ID P21579) for use in western blot, immunoprecipitation, immunofluorescence and flow cytometry MS Biddle, C Alende, M Fotouhi, C Jones, R Ayoubi, K Southern, ... F1000Research 13, 817, 2024 | 1 | 2024 |
DP2/CRTh2 is expressed by ASM cells in asthma and its inhibition suppresses ASM migration R Saunders, M Biddle, A Wright, L Chachi, A Sutcliffe, R Berair, ... European Respiratory Journal 48 (suppl 60), 2016 | 1 | 2016 |
BS59 The k+ channel KCa3. 1 as a novel target for aortic stenosis M Whitfield, S Aslam, M Biddle, JG De Sousa, D Taveira, MS Duffy, ... Heart 110 (Suppl 3), A286-A287, 2024 | | 2024 |
Improving the integrity and reproducibility of research that uses antibodies: a technical, data sharing, behavioral and policy challenge H Virk, M Biddle, M Rekas, P Stylianou, A Wright, J Sousa, D Ruddy, ... University of Leicester, 2024 | | 2024 |
The role of NADPH oxidases in airway smooth muscle from asthmatics and COPD patients M Biddle University of Leicester, 2022 | | 2022 |