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John W. Bullen, Ph.D.
John W. Bullen, Ph.D.
Associate Director, AstraZeneca
Bestätigte E-Mail-Adresse bei astrazeneca.com
Titel
Zitiert von
Zitiert von
Jahr
Recombinant human leptin in women with hypothalamic amenorrhea
CK Welt, JL Chan, J Bullen, R Murphy, P Smith, AM DePaoli, A Karalis, ...
New England Journal of Medicine 351 (10), 987-997, 2004
10842004
Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m6A-demethylation of NANOG mRNA
C Zhang, D Samanta, H Lu, JW Bullen, H Zhang, I Chen, X He, ...
Proceedings of the National Academy of Sciences 113 (14), E2047-E2056, 2016
10712016
HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells
H Zhang, H Lu, L Xiang, JW Bullen, C Zhang, D Samanta, DM Gilkes, ...
Proceedings of the National Academy of Sciences 112 (45), E6215-E6223, 2015
4102015
Circulating adiponectin and expression of adiponectin receptors in human skeletal muscle: associations with metabolic parameters and insulin resistance and regulation by …
M Blüher, JW Bullen Jr, JH Lee, S Kralisch, M Fasshauer, N Klöting, ...
The Journal of Clinical Endocrinology & Metabolism 91 (6), 2310-2316, 2006
4022006
Cross-talk between GlcNAcylation and phosphorylation: roles in insulin resistance and glucose toxicity
RJ Copeland, JW Bullen, GW Hart
American Journal of Physiology-Endocrinology and Metabolism 295 (1), E17-E28, 2008
3242008
Total and High-Molecular-Weight Adiponectin in Breast Cancer: In Vitro and in Vivo Studies
A Körner, K Pazaitou-Panayiotou, T Kelesidis, I Kelesidis, CJ Williams, ...
The Journal of Clinical Endocrinology & Metabolism 92 (3), 1041-1048, 2007
2962007
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
H Lu, D Samanta, L Xiang, H Zhang, H Hu, I Chen, JW Bullen, ...
Proceedings of the National Academy of Sciences 112 (33), E4600-E4609, 2015
2682015
Cross-talk between two essential nutrient-sensitive enzymes: O-GlcNAc transferase (OGT) and AMP-activated protein kinase (AMPK)
JW Bullen, JL Balsbaugh, D Chanda, J Shabanowitz, DF Hunt, ...
Journal of Biological Chemistry 289 (15), 10592-10606, 2014
2332014
Ghrelin levels are not regulated by recombinant leptin administration and/or three days of fasting in healthy subjects
JL Chan, J Bullen, JH Lee, N Yiannakouris, CS Mantzoros
The Journal of Clinical Endocrinology & Metabolism 89 (1), 335-343, 2004
2152004
Regulation of adiponectin and its receptors in response to development of diet-induced obesity in mice
JW Bullen Jr, S Bluher, T Kelesidis, CS Mantzoros
American Journal of Physiology-Endocrinology and Metabolism 292 (4), E1079-E1086, 2007
1992007
Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype
L Xiang, DM Gilkes, H Hu, N Takano, W Luo, H Lu, JW Bullen, D Samanta, ...
Oncotarget 5 (24), 12509, 2014
1322014
Circulating resistin in lean, obese, and insulin-resistant mouse models: lack of association with insulinemia and glycemia
JH Lee, JW Bullen Jr, VL Stoyneva, CS Mantzoros
American Journal of Physiology-Endocrinology and Metabolism 288 (3), E625-E632, 2005
1322005
Protein kinase A–dependent phosphorylation stimulates the transcriptional activity of hypoxia-inducible factor 1
JW Bullen, I Tchernyshyov, RJ Holewinski, L DeVine, F Wu, ...
Science signaling 9 (430), ra56-ra56, 2016
1262016
Responsiveness to peripherally administered melanocortins in lean and obese mice
S Bluher, M Ziotopoulou, JW Bullen Jr, SJ Moschos, L Ungsunan, ...
Diabetes 53 (1), 82-90, 2004
992004
Recombinant methionyl human leptin administration to achieve high physiologic or pharmacologic leptin levels does not alter circulating inflammatory marker levels in humans …
JL Chan, J Bullen, V Stoyneva, AM DePaoli, C Addy, CS Mantzoros
The Journal of Clinical Endocrinology & Metabolism 90 (3), 1618-1624, 2005
872005
HIF-1α and TAZ serve as reciprocal co-activators in human breast cancer cells
L Xiang, DM Gilkes, H Hu, W Luo, JW Bullen, H Liang, GL Semenza
Oncotarget 6 (14), 11768, 2015
792015
Ciliary Neurotrophic FactorAx15 Alters Energy Homeostasis, Decreases Body Weight, and Improves Metabolic Control in Diet-Induced Obese and UCP1-DTA Mice
S Bluher, S Moschos, J Bullen Jr, E Kokkotou, E Maratos-Flier, ...
Diabetes 53 (11), 2787-2796, 2004
772004
Recombinant methionyl human leptin administration activates signal transducer and activator of transcription 3 signaling in peripheral blood mononuclear cells in vivo and …
JL Chan, SJ Moschos, J Bullen, K Heist, X Li, YB Kim, BB Kahn, ...
The Journal of Clinical Endocrinology & Metabolism 90 (3), 1625-1631, 2005
692005
Myelin-associated glycoprotein (MAG) protects neurons from acute toxicity using a ganglioside-dependent mechanism
NR Mehta, T Nguyen, JW Bullen Jr, JW Griffin, RL Schnaar
ACS chemical neuroscience 1 (3), 215-222, 2010
452010
Elevated leptin fragments in renal failure correlate with BMI and haematopoiesis and are normalized by haemodialysis
DN Stamatiadis, JL Chan, R Cogswell, HC Stefanopoulou, J Bullen, ...
Clinical endocrinology 60 (4), 434-441, 2004
392004
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