| Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons Y Shi, S Lin, KA Staats, Y Li, WH Chang, ST Hung, E Hendricks, ... Nature medicine 24 (3), 313-325, 2018 | 621 | 2018 |
| Regulation of induced pluripotent stem (iPS) cell induction by Wnt/β-catenin signaling P Zhang, WH Chang, B Fong, F Gao, C Liu, D Al Alam, S Bellusci, W Lu Journal of Biological Chemistry 289 (13), 9221-9232, 2014 | 64 | 2014 |
| PIKFYVE inhibition mitigates disease in models of diverse forms of ALS ST Hung, GR Linares, WH Chang, Y Eoh, G Krishnan, S Mendonca, ... Cell 186 (4), 786-802. e28, 2023 | 53 | 2023 |
| Maf1 and repression of RNA polymerase III-mediated transcription drive adipocyte differentiation CY Chen, RB Lanz, CJ Walkey, WH Chang, W Lu, DL Johnson Cell reports 24 (7), 1852-1864, 2018 | 32 | 2018 |
| Smek promotes corticogenesis through regulating Mbd3’s stability and Mbd3/NuRD complex recruitment to genes associated with neurogenesis BS Moon, HM Yun, WH Chang, BH Steele, M Cai, SH Choi, W Lu PLoS Biology 15 (5), e2001220, 2017 | 30 | 2017 |
| Smek1/2 is a nuclear chaperone and cofactor for cleaved Wnt receptor Ryk, regulating cortical neurogenesis WH Chang, SH Choi, BS Moon, M Cai, J Lyu, J Bai, F Gao, I Hajjali, ... Proceedings of the National Academy of Sciences 114 (50), E10717-E10725, 2017 | 29 | 2017 |
| Biological implications and regulatory mechanisms of long-range chromosomal interactions Z Wei, D Huang, F Gao, WH Chang, W An, GA Coetzee, K Wang, W Lu Journal of Biological Chemistry 288 (31), 22369-22377, 2013 | 27 | 2013 |
| SYF2 suppression mitigates neurodegeneration in models of diverse forms of ALS GR Linares, Y Li, WH Chang, J Rubin-Sigler, S Mendonca, S Hong, Y Eoh, ... Cell Stem Cell 30 (2), 171-187. e14, 2023 | 22 | 2023 |
| The M1311V variant of ATP7A is associated with impaired trafficking and copper homeostasis in models of motor neuron disease N Bakkar, A Starr, BE Rabichow, I Lorenzini, ZT McEachin, R Kraft, ... Neurobiology of disease 149, 105228, 2021 | 22 | 2021 |
| Small molecule inhibition of PIKFYVE kinase rescues gain- and loss-of-function C9ORF72 ALS/FTD disease processes in vivo KA Staats, C Seah, A Sahimi, Y Wang, N Koutsodendris, S Lin, D Kim, ... BioRxiv, 685800, 2019 | 22 | 2019 |
| Fangchinoline inhibits glutamate release from rat cerebral cortex nerve terminals (synaptosomes) TY Lin, CW Lu, LT Tien, SH Chuang, YR Wang, WH Chang, SJ Wang Neurochemistry international 54 (8), 506-512, 2009 | 22 | 2009 |
| Unc13a antisense oligonucleotides WH Chang, JK Ichida US Patent App. 17/870,754, 2023 | | 2023 |
| Pikfyve antisense oligonucleotides WH Chang, EE Lee US Patent App. 17/808,247, 2022 | | 2022 |
| Method for identifying effective treatments against neurodegenerative disorders JK Ichida, H Zhou, WH Chang, SV Alworth US Patent App. 16/732,109, 2021 | | 2021 |
| Establishment of inducible iPS cells for tissue engineering for cancer therapy AL Miao, W Chang, W Lu ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 243, 2012 | | 2012 |
