Fructose-1, 6-bisphosphate and aldolase mediate glucose sensing by AMPK CS Zhang, SA Hawley, Y Zong, M Li, Z Wang, A Gray, T Ma, J Cui, ... Nature 548 (7665), 112-116, 2017 | 651 | 2017 |
The lysosomal v-ATPase-Ragulator complex is a common activator for AMPK and mTORC1, acting as a switch between catabolism and anabolism CS Zhang, B Jiang, M Li, M Zhu, Y Peng, YL Zhang, YQ Wu, TY Li, ... Cell metabolism 20 (3), 526-540, 2014 | 563 | 2014 |
GSK3-TIP60-ULK1 signaling pathway links growth factor deprivation to autophagy SY Lin, TY Li, Q Liu, C Zhang, X Li, Y Chen, SM Zhang, G Lian, Q Liu, ... Science 336 (6080), 477-481, 2012 | 403 | 2012 |
Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activity J Geng, X Sun, P Wang, S Zhang, X Wang, H Wu, L Hong, C Xie, X Li, ... Nature immunology 16 (11), 1142-1152, 2015 | 262 | 2015 |
The NAD-booster nicotinamide riboside potently stimulates hematopoiesis through increased mitochondrial clearance N Vannini, V Campos, M Girotra, V Trachsel, S Rojas-Sutterlin, J Tratwal, ... Cell stem cell 24 (3), 405-418. e7, 2019 | 205 | 2019 |
The orphan nuclear receptor Nur77 regulates LKB1 localization and activates AMPK Y Zhan, Y Chen, Q Zhang, J Zhuang, M Tian, H Chen, L Zhang, H Zhang, ... Nature chemical biology 8 (11), 897-904, 2012 | 191 | 2012 |
The Ets transcription factor GABP is a component of the hippo pathway essential for growth and antioxidant defense H Wu, Y Xiao, S Zhang, S Ji, L Wei, F Fan, J Geng, J Tian, X Sun, F Qin, ... Cell reports 3 (5), 1663-1677, 2013 | 144 | 2013 |
Pleiotropic effects of mitochondria in aging T Lima, TY Li, A Mottis, J Auwerx Nature aging 2 (3), 199-213, 2022 | 143 | 2022 |
ULK1/2 constitute a bifurcate node controlling glucose metabolic fluxes in addition to autophagy TY Li, Y Sun, Y Liang, Q Liu, Y Shi, CS Zhang, C Zhang, L Song, P Zhang, ... Molecular cell 62 (3), 359-370, 2016 | 126 | 2016 |
Tip60-mediated lipin 1 acetylation and ER translocation determine triacylglycerol synthesis rate TY Li, L Song, Y Sun, J Li, C Yi, SM Lam, D Xu, L Zhou, X Li, Y Yang, ... Nature communications 9 (1), 1916, 2018 | 70 | 2018 |
The transcriptional coactivator CBP/p300 is an evolutionarily conserved node that promotes longevity in response to mitochondrial stress TY Li, MB Sleiman, H Li, AW Gao, A Mottis, AM Bachmann, GE Alam, X Li, ... Nature aging 1 (2), 165-178, 2021 | 63 | 2021 |
Proto-oncogene Src links lipogenesis via lipin-1 to breast cancer malignancy L Song, Z Liu, HH Hu, Y Yang, TY Li, ZZ Lin, J Ye, J Chen, X Huang, ... Nature communications 11 (1), 5842, 2020 | 60 | 2020 |
RHOBTB3 promotes proteasomal degradation of HIFα through facilitating hydroxylation and suppresses the Warburg effect CS Zhang, Q Liu, M Li, SY Lin, Y Peng, D Wu, TY Li, Q Fu, W Jia, X Wang, ... Cell Research 25 (9), 1025-1042, 2015 | 57 | 2015 |
AIDA selectively mediates downregulation of fat synthesis enzymes by ERAD to retard intestinal fat absorption and prevent obesity H Luo, M Jiang, G Lian, Q Liu, M Shi, TY Li, L Song, J Ye, Y He, L Yao, ... Cell metabolism 27 (4), 843-853. e6, 2018 | 55 | 2018 |
Identifying gene function and module connections by the integration of multispecies expression compendia H Li, D Rukina, FPA David, TY Li, CM Oh, AW Gao, E Katsyuba, ... Genome Research 29 (12), 2034-2045, 2019 | 42 | 2019 |
Liver‐specific deficiency of unc‐51 like kinase 1 and 2 protects mice from acetaminophen‐induced liver injury Y Sun, TY Li, L Song, C Zhang, J Li, ZZ Lin, SC Lin, SY Lin Hepatology 67 (6), 2397-2413, 2018 | 39 | 2018 |
Protein phosphorylation-acetylation cascade connects growth factor deprivation to autophagy SY Lin, TY Li, Q Liu, C Zhang, X Li, Y Chen, SM Zhang, G Lian, Q Liu, ... Autophagy 8 (9), 1385-1386, 2012 | 31 | 2012 |
Tetracycline-induced mitohormesis mediates disease tolerance against influenza A Mottis, TY Li, G El Alam, A Rapin, E Katsyuba, D Liaskos, D D’Amico, ... The Journal of Clinical Investigation 132 (17), 2022 | 23 | 2022 |
Lysosomes mediate the mitochondrial UPR via mTORC1-dependent ATF4 phosphorylation TY Li, Q Wang, AW Gao, X Li, Y Sun, A Mottis, M Shong, J Auwerx Cell Discovery 9 (1), 92, 2023 | 17 | 2023 |
Mechanism and physiological significance of growth factor-related autophagy TY Li, SY Lin, SC Lin Physiology 28 (6), 423-431, 2013 | 17 | 2013 |