| Rational design and synthesis of novel dual PROTACs for simultaneous degradation of EGFR and PARP M Zheng, J Huo, X Gu, Y Wang, C Wu, Q Zhang, W Wang, Y Liu, Y Liu, ... Journal of Medicinal Chemistry 64 (11), 7839-7852, 2021 | 141 | 2021 |
| Design, synthesis, and evaluation of PD-L1 degraders to enhance T cell killing activity against melanoma Y Liu, M Zheng, Z Ma, Y Zhou, J Huo, W Zhang, Y Liu, Y Guo, X Zhou, H Li, ... Chinese Chemical Letters 34 (5), 107762, 2023 | 36 | 2023 |
| EMT and cancer cell stemness associated with chemotherapeutic resistance in esophageal cancer X Liu, M He, L Li, X Wang, S Han, J Zhao, Y Dong, M Ahmad, L Li, ... Frontiers in Oncology 11, 672222, 2021 | 35 | 2021 |
| Structure-Based Design, Synthesis, and Biological Evaluation of New Triazolo[1,5-a]Pyrimidine Derivatives as Highly Potent and Orally Active ABCB1 Modulators S Wang, SQ Wang, QX Teng, L Yang, ZN Lei, XH Yuan, JF Huo, XB Chen, ... Journal of Medicinal Chemistry 63 (24), 15979-15996, 2020 | 34 | 2020 |
| SIRT1 expression regulates the transformation of resistant esophageal cancer cells via the epithelial-mesenchymal transition T Qin, W Liu, J Huo, L Li, X Zhang, X Shi, J Zhou, C Wang Biomedicine & Pharmacotherapy 103, 308-316, 2018 | 22 | 2018 |
| Discovery of chalcone-modified estradiol analogs as antitumour agents that Inhibit tumour angiogenesis and epithelial to mesenchymal transition C Wang, L Li, D Fu, T Qin, Y Ran, F Xu, X Du, H Gao, S Sun, T Yang, ... European Journal of Medicinal Chemistry 176, 135-148, 2019 | 21 | 2019 |
| Luteolin combined with low‐dose paclitaxel synergistically inhibits epithelial–mesenchymal transition and induces cell apoptosis on esophageal carcinoma in vitro and in vivo T Qin, J Zhao, X Liu, L Li, X Zhang, X Shi, Y Ke, W Liu, J Huo, Y Dong, ... Phytotherapy Research 35 (11), 6228-6240, 2021 | 19 | 2021 |
| Synthesis and in vitro biological evaluation of novel derivatives of Flexicaulin A condensation with amino acid trifluoroacetate Y Ke, TX Hu, JF Huo, JK Yan, JY Wang, RH Yang, H Xie, Y Liu, N Wang, ... European Journal of Medicinal Chemistry 182, 111645, 2019 | 11 | 2019 |
| Distinguishing G-Quadruplexes Stabilizer and Chaperone for c-MYC Promoter G-Quadruplexes through Single-Molecule Manipulation Y Zhang, Y Cheng, Q Luo, T Wu, J Huo, M Yin, H Peng, Y Xiao, Q Tong, ... Journal of the American Chemical Society 146 (6), 3689-3699, 2024 | 7 | 2024 |
| Synthesis and in vitro and in vivo biological evaluation of novel derivatives of flexicaulin A as antiproliferative agents JF Huo, TX Hu, YL Dong, JZ Zhao, XJ Liu, LL Li, XY Zhang, YF Li, HM Liu, ... European Journal of Medicinal Chemistry 208, 112789, 2020 | 5 | 2020 |
| Selective anticancer activity of the novel steroidal dihydropyridine spirooxindoles against human esophageal EC109 cells X Shi, T Qin, W Liu, X Zhang, L Li, J Huo, K Zhou, D Yang, Y Zhang, ... Biomedicine & Pharmacotherapy 96, 1186-1192, 2017 | 5 | 2017 |
| The mechanism by which SIRT1 regulates autophagy and EMT in drug-resistant oesophageal cancer cells X Zhang, Y Dong, W Li, M He, Y Shi, S Han, L Li, J Zhao, L Li, J Huo, X Liu, ... Life Sciences 343, 122530, 2024 | 3 | 2024 |
| Force-enhanced sensitive and specific detection of DNA-intercalative agents directly from microorganisms at single-molecule level T Liu, T Cai, J Huo, H Liu, A Li, M Yin, Y Mei, Y Zhou, S Fan, Y Lu, L Wan, ... Nucleic Acids Research 52 (18), e86-e86, 2024 | 1 | 2024 |
| Discovery of linear unnatural peptides as potent mutant isocitrate dehydrogenase 1 inhibitors by Ugi reaction X Zhou, M Zheng, N Zhao, Y Hu, K Yang, J Huo, G Liu, J Huang, L Chen, ... Bioorganic Chemistry 119, 105569, 2022 | 1 | 2022 |
| Force-Enhanced Sensitive Detection of New DNA-Interactive Agents from Microorganisms at the Single-Molecule Level T Liu, T Cai, H Liu, A Li, M Yin, Y Mei, Y Zhou, S Fan, Y Lu, L Wan, H You, ... bioRxiv, 2024.04. 22.590585, 2024 | | 2024 |
Hong-Min LiuZhengzhou UniversityBestätigte E-Mail-Adresse bei zzu.edu.cn