Voltage-gated potassium channels as therapeutic targets H Wulff, NA Castle, LA Pardo Nature reviews Drug discovery 8 (12), 982-1001, 2009 | 927 | 2009 |
Design of a potent and selective inhibitor of the intermediate-conductance Ca2+-activated K+ channel, IKCa1: A potential immunosuppressant H Wulff, MJ Miller, W Hänsel, S Grissmer, MD Cahalan, KG Chandy Proceedings of the National Academy of Sciences 97 (14), 8151-8156, 2000 | 757 | 2000 |
Ion channels in innate and adaptive immunity S Feske, H Wulff, EY Skolnik Annual review of immunology 33 (1), 291-353, 2015 | 734 | 2015 |
Kv1. 3 channels are a therapeutic target for T cell-mediated autoimmune diseases C Beeton, H Wulff, NE Standifer, P Azam, KM Mullen, MW Pennington, ... Proceedings of the National Academy of Sciences 103 (46), 17414-17419, 2006 | 625 | 2006 |
The voltage-gated Kv1.3 K+ channel in effector memory T cells as new target for MS H Wulff, PA Calabresi, R Allie, S Yun, M Pennington, C Beeton, ... The Journal of clinical investigation 111 (11), 1703-1713, 2003 | 567 | 2003 |
K+ channels as targets for specific immunomodulation KG Chandy, H Wulff, C Beeton, M Pennington, GA Gutman, MD Cahalan Trends in pharmacological sciences 25 (5), 280-289, 2004 | 564 | 2004 |
International Union of Pharmacology. LII. Nomenclature and molecular relationships of calcium-activated potassium channels AD Wei, GA Gutman, R Aldrich, KG Chandy, S Grissmer, H Wulff Pharmacological reviews 57 (4), 463-472, 2005 | 524 | 2005 |
Up-regulation of the IKCa1 potassium channel during T-cell activation: molecular mechanism and functional consequences S Ghanshani, H Wulff, MJ Miller, H Rohm, A Neben, GA Gutman, ... Journal of Biological Chemistry 275 (47), 37137-37149, 2000 | 519 | 2000 |
International Union of Pharmacology. XLI. Compendium of voltage-gated ion channels: potassium channels GA Gutman, KG Chandy, JP Adelman, J Aiyar, DA Bayliss, DE Clapham, ... Pharmacological reviews 55 (4), 583-586, 2003 | 472 | 2003 |
Selective blockade of T lymphocyte K+ channels ameliorates experimental autoimmune encephalomyelitis, a model for multiple sclerosis C Beeton, H Wulff, J Barbaria, O Clot-Faybesse, M Pennington, D Bernard, ... Proceedings of the national academy of sciences 98 (24), 13942-13947, 2001 | 457 | 2001 |
A non-hallucinogenic psychedelic analogue with therapeutic potential LP Cameron, RJ Tombari, J Lu, AJ Pell, ZQ Hurley, Y Ehinger, MV Vargas, ... Nature 589 (7842), 474-479, 2021 | 376 | 2021 |
The concise guide to pharmacology 2017/18: overview SPH Alexander, E Kelly, NV Marrion, JA Peters, E Faccenda, SD Harding, ... British journal of pharmacology 174, S1-S16, 2017 | 372 | 2017 |
The concise guide to pharmacology 2019/20: Ion channels SPH Alexander, A Mathie, JA Peters, EL Veale, J Striessnig, E Kelly, ... British journal of pharmacology 176, S142-S228, 2019 | 367 | 2019 |
Amyloid-β protein oligomer at low nanomolar concentrations activates microglia and induces microglial neurotoxicity I Maezawa, PI Zimin, H Wulff, LW Jin Journal of Biological Chemistry 286 (5), 3693-3706, 2011 | 351 | 2011 |
Targeting effector memory T cells with a selective peptide inhibitor of Kv1. 3 channels for therapy of autoimmune diseases C Beeton, MW Pennington, H Wulff, S Singh, D Nugent, G Crossley, ... Molecular pharmacology 67 (4), 1369-1381, 2005 | 344 | 2005 |
Molecular properties and physiological roles of ion channels in the immune system MD Cahalan, H Wulff, KG Chandy Journal of clinical immunology 21, 235-252, 2001 | 328 | 2001 |
Blockade of the intermediate-conductance calcium-activated potassium channel as a new therapeutic strategy for restenosis R Köhler, H Wulff, I Eichler, M Kneifel, D Neumann, A Knorr, I Grgic, ... Circulation 108 (9), 1119-1125, 2003 | 298 | 2003 |
The concise guide to PHARMACOLOGY 2015/16: Overview SPH Alexander, E Kelly, N Marrion, JA Peters, HE Benson, E Faccenda, ... British journal of pharmacology 172 (24), 5729-5743, 2015 | 292 | 2015 |
Design of PAP-1, a selective small molecule Kv1. 3 blocker, for the suppression of effector memory T cells in autoimmune diseases A Schmitz, A Sankaranarayanan, P Azam, K Schmidt-Lassen, D Homerick, ... Molecular pharmacology 68 (5), 1254-1270, 2005 | 287 | 2005 |
Genetic deficit of SK3 and IK1 channels disrupts the endothelium-derived hyperpolarizing factor vasodilator pathway and causes hypertension S Brähler, A Kaistha, VJ Schmidt, SE Wölfle, C Busch, BP Kaistha, ... Circulation 119 (17), 2323-2332, 2009 | 278 | 2009 |