Molecular mechanism of PPARα action and its impact on lipid metabolism, inflammation and fibrosis in non-alcoholic fatty liver disease M Pawlak, P Lefebvre, B Staels Journal of Hepatology, 2015 | 1431 | 2015 |
PPARs in obesity-induced T2DM, dyslipidaemia and NAFLD B Gross, M Pawlak, P Lefebvre, B Staels Nature Reviews Endocrinology, 2016 | 691 | 2016 |
General molecular biology and architecture of nuclear receptors M Pawlak, P Lefebvre, B Staels Current Topics in Medicinal Chemistry, 2012 | 205 | 2012 |
In vivo partial reprogramming alters age-associated molecular changes during physiological aging in mice KC Browder, P Reddy, M Yamamoto, A Haghani, IG Guillen, S Sahu, ... Nature Aging 2 (3), 243-253, 2022 | 163 | 2022 |
The transrepressive activity of peroxisome proliferator-activated receptor alpha is necessary and sufficient to prevent liver fibrosis in mice M Pawlak, E Baugé, W Bourguet, K De Bosscher, F Lalloyer, A Tailleux, ... Hepatology, 2014 | 139 | 2014 |
Interspecies NASH disease activity whole-genome profiling identifies a fibrogenic role of PPARα-regulated dermatopontin P Lefebvre, F Lalloyer, E Baugé, M Pawlak, C Gheeraert, H Dehondt, ... Journal of Clinical Investigation Insights, 2017 | 123 | 2017 |
Chromatin recruitment of activated AMPK drives fasting response genes co-controlled by GR and PPARα D Ratman, V Mylka, N Bougarne, M Pawlak, S Caron, N Hennuyer, ... Nucleic Acids Research, 2016 | 66 | 2016 |
Integration of ligand and structure-based virtual screening for the identification of the first dual targeting agent for heat shock protein 90 (Hsp90) and tubulin AJS Knox, T Price, M Pawlak, G Golfis, CT Flood, D Fayne, DC Williams, ... Journal of medicinal chemistry 52 (8), 2177-2180, 2009 | 49 | 2009 |
Age-related changes in polycomb gene regulation disrupt lineage fidelity in intestinal stem cells HM Tauc, IA Rodriguez-Fernandez, JA Hackney, M Pawlak, ... Elife 10, e62250, 2021 | 40 | 2021 |
Ketone Body Therapy Protects From Lipotoxicity and Acute Liver Failure Upon Pparα Deficiency M Pawlak, E Baugé, F Lalloyer, P Lefebvre, B Staels Molecular Endocrinology, 2015 | 34 | 2015 |
Dynamics of cardiomyocyte transcriptome and chromatin landscape demarcates key events of heart development M Pawlak, KZ Kedzierska, M Migdal, KA Nahia, JA Ramilowski, ... Genome research 29 (3), 506-519, 2019 | 29 | 2019 |
Inhibition of PIM kinases in DLBCL targets MYC transcriptional program and augments the efficacy of anti-CD20 antibodies M Szydłowski, F Garbicz, E Jabłońska, P Górniak, D Komar, B Pyrzyńska, ... Cancer Research 81 (23), 6029-6043, 2021 | 26 | 2021 |
Decoding the Heart through Next Generation Sequencing Approaches M Pawlak, K Niescierowicz, CL Winata Genes (Basel) 9 (6), 2018 | 25 | 2018 |
The elongation complex components BRD4 and MLLT3/AF9 are transcriptional coactivators of nuclear retinoid receptors S Flajollet, C Rachez, M Ploton, C Schulz, R Gallais, R Métivier, M Pawlak, ... Plos One, 2013 | 18 | 2013 |
Genomic and physiological analyses of the zebrafish atrioventricular canal reveal molecular building blocks of the secondary pacemaker region K Abu Nahia, M Migdał, TA Quinn, KL Poon, M Łapiński, A Sulej, J Liu, ... Cellular and Molecular Life Sciences 78, 6669-6687, 2021 | 13 | 2021 |
Multi-omics analyses of early liver injury reveals cell-type-specific transcriptional and epigenomic shift M Migdał, E Tralle, KA Nahia, Ł Bugajski, KZ Kędzierska, F Garbicz, ... BMC genomics 22, 1-15, 2021 | 8 | 2021 |
Tracking clonal evolution of multiple myeloma using targeted next-generation DNA sequencing A Salomon-Perzyński, J Barankiewicz, M Machnicki, ... Biomedicines 10 (7), 1674, 2022 | 6 | 2022 |
PIM Kinase Inhibition Decreases the Proangiogenic Properties of Multiple Myeloma Cells and Affects the Metabolic State of the Vascular Endothelium F Garbicz, A Szumera-Ciećkiewicz, J Barankiewicz, D Komar, M Pawlak, ... Blood 136, 16-17, 2020 | 2 | 2020 |
P263 STEATOSIS-INDEPENDENT PREVENTION OF LIVER FIBROSIS VIA THE TRANSREPRESSIVE ACTIVITY OF PPARa M Pawlak, E Bauge, W Bourguet, K De Bosscher, F Lalloyer, A Tailleux, ... Journal of Hepatology 1 (60), S152-S153, 2014 | 2 | 2014 |
PIM Kinases Regulate Super-Enhancer-Dependent Gene Expression in Diffuse Large B-Cell Lymphoma S Debek, D Komar, F Garbicz, A Matrejek, M Pawlak, E Jabłońska, ... Blood 140 (Supplement 1), 3044-3045, 2022 | 1 | 2022 |