A reversible RNA on-switch that controls gene expression of AAV-delivered therapeutics in vivo G Zhong, H Wang, W He, Y Li, H Mou, ZJ Tickner, MH Tran, T Ou, Y Yin, ... Nature biotechnology 38 (2), 169-175, 2020 | 88 | 2020 |
In vitro affinity maturation of broader and more-potent variants of the HIV-1–neutralizing antibody CAP256-VRC26. 25 Y Yin, BD Quinlan, T Ou, Y Guo, W He, M Farzan Proceedings of the National Academy of Sciences 118 (29), e2106203118, 2021 | 14 | 2021 |
Reprogramming of the heavy-chain CDR3 regions of a human antibody repertoire T Ou, W He, BD Quinlan, Y Guo, MH Tran, P Karunadharma, H Park, ... Molecular Therapy 30 (1), 184-197, 2022 | 13 | 2022 |
Heavy-chain CDR3-engineered B cells facilitate in vivo evaluation of HIV-1 vaccine candidates W He, T Ou, N Skamangas, CC Bailey, N Bronkema, Y Guo, Y Yin, ... Immunity 56 (10), 2408-2424. e6, 2023 | 6 | 2023 |
In vivo affinity maturation of mouse B cells reprogrammed to express human antibodies Y Yin, Y Guo, Y Jiang, B Quinlan, H Peng, G Crynen, W He, L Zhang, T Ou, ... Nature Biomedical Engineering 8 (4), 361-379, 2024 | 3 | 2024 |
In vivo affinity maturation of murine B cells reprogrammed to express human antibodies Y Yin, Y Guo, Y Jiang, B Quinlan, H Peng, G Crynen, W He, L Zhang, T Ou, ... bioRxiv, 2023 | 1 | 2023 |
In vivo affinity maturation of the CD4 domains of an HIV-1-entry inhibitor A Pan, CC Bailey, T Ou, J Xu, T Aristotelous, X Liu, B Hu, G Crynen, ... Nature Biomedical Engineering 8 (12), 1715-1729, 2024 | | 2024 |
Research briefing Y Yin, M Farzan Nature 8, 341-342, 2024 | | 2024 |
Affinity maturation of CRISPR-engineered B cell receptors in vivo Y Yin, M Farzan NATURE BIOMEDICAL ENGINEERING, 2024 | | 2024 |
In vivo affinity maturation of the HIV-1 Env-binding domain of CD4 A Pan, CC Bailey, T Ou, J Xu, X Liu, B Hu, G Crynen, N Skamangas, ... Research Square, rs. 3. rs-3922904, 2024 | | 2024 |
In vitro and in vivo Affinity Maturation of Edited B Cells Expressing HIV-1 Broadly Neutralizing Antibodies Y Yin The Scripps Research Institute, 2023 | | 2023 |
Efficient reprogramming of the heavy-chain CDR3 regions of a human antibody repertoire T Ou, W He, BD Quinlan, Y Guo, P Karunadharma, H Park, ... bioRxiv, 2021.04. 01.437943, 2021 | | 2021 |