| Hypoxia-induced endocytosis of Na, K-ATPase in alveolar epithelial cells is mediated by mitochondrial reactive oxygen species and PKC-ζ LA Dada, NS Chandel, KM Ridge, C Pedemonte, AM Bertorello, ... The Journal of clinical investigation 111 (7), 1057-1064, 2003 | 369 | 2003 |
| Hypoxia-induced alveolar epithelial-mesenchymal transition requires mitochondrial ROS and hypoxia-inducible factor 1 G Zhou, LA Dada, M Wu, A Kelly, H Trejo, Q Zhou, J Varga, JI Sznajder American Journal of Physiology-Lung Cellular and Molecular Physiology 297 (6 …, 2009 | 270 | 2009 |
| AMP-activated protein kinase regulates CO2-induced alveolar epithelial dysfunction in rats and human cells by promoting Na,K-ATPase endocytosis I Vadász, LA Dada, A Briva, HE Trejo, LC Welch, J Chen, PT Tóth, ... The Journal of clinical investigation 118 (2), 752-762, 2008 | 206 | 2008 |
| Hypoxia Leads to Na,K-ATPase Downregulation via Ca2+ Release-Activated Ca2+ Channels and AMPK Activation GA Gusarova, HE Trejo, LA Dada, A Briva, LC Welch, RB Hamanaka, ... Molecular and cellular biology 31 (17), 3546-3556, 2011 | 189 | 2011 |
| α1-AMP-activated protein kinase regulates hypoxia-induced Na, K-ATPase endocytosis via direct phosphorylation of protein kinase Cζ GA Gusarova, LA Dada, AM Kelly, C Brodie, LA Witters, NS Chandel, ... Molecular and cellular biology 29 (13), 3455-3464, 2009 | 142 | 2009 |
| Hypoxia-mediated degradation of Na, K-ATPase via mitochondrial reactive oxygen species and the ubiquitin-conjugating system AP Comellas, LA Dada, E Lecuona, LM Pesce, NS Chandel, N Quesada, ... Circulation research 98 (10), 1314-1322, 2006 | 141 | 2006 |
| High CO2 Levels Impair Alveolar Epithelial Function Independently of pH A Briva, I Vadász, E Lecuona, LC Welch, J Chen, LA Dada, HE Trejo, ... PloS one 2 (11), e1238, 2007 | 136 | 2007 |
| High CO2 levels cause skeletal muscle atrophy via AMP-activated kinase (AMPK), FoxO3a protein, and muscle-specific Ring finger protein 1 (MuRF1) A Jaitovich, M Angulo, E Lecuona, LA Dada, LC Welch, Y Cheng, ... Journal of Biological Chemistry 290 (14), 9183-9194, 2015 | 129 | 2015 |
| The Na-K-ATPase α1β1 heterodimer as a cell adhesion molecule in epithelia O Vagin, LA Dada, E Tokhtaeva, G Sachs American Journal of Physiology-Cell Physiology 302 (9), C1271-C1281, 2012 | 124 | 2012 |
| Dopamine-induced exocytosis of Na, K-ATPase is dependent on activation of protein kinase C-ε and-δ KM Ridge, L Dada, E Lecuona, AM Bertorello, AI Katz, D Mochly-Rosen, ... Molecular biology of the cell 13 (4), 1381-1389, 2002 | 123 | 2002 |
| Septin dynamics are essential for exocytosis E Tokhtaeva, J Capri, EA Marcus, JP Whitelegge, V Khuzakhmetova, ... Journal of Biological Chemistry 290 (9), 5280-5297, 2015 | 95 | 2015 |
| Effect of nitric oxide on rat adrenal zona fasciculata steroidogenesis CB Cymeryng, LA Dada, EJ Podesta Journal of Endocrinology 158 (2), 197-204, 1998 | 94 | 1998 |
| Mitochondrial Ca2+ and ROS take center stage to orchestrate TNF-α–mediated inflammatory responses LA Dada, JI Sznajder The Journal of clinical investigation 121 (5), 1683-1685, 2011 | 89 | 2011 |
| Mechanisms of pulmonary edema clearance during acute hypoxemic respiratory failure: role of the Na, K-ATPase LA Dada, JI Sznajder Critical care medicine 31 (4), S248-S252, 2003 | 71 | 2003 |
| Regulation of alveolar epithelial function by hypoxia G Zhou, LA Dada, JI Sznajder European Respiratory Journal 31 (5), 1107-1113, 2008 | 70 | 2008 |
| Mitochondrial integrated stress response controls lung epithelial cell fate SH Han, M Lee, Y Shin, R Giovanni, RP Chakrabarty, MM Herrerias, ... Nature 620 (7975), 890-897, 2023 | 67 | 2023 |
| The kinase Jnk2 promotes stress-induced mitophagy by targeting the small mitochondrial form of the tumor suppressor ARF for degradation Q Zhang, H Kuang, C Chen, J Yan, HC Do-Umehara, X Liu, L Dada, ... Nature immunology 16 (5), 458-466, 2015 | 64 | 2015 |
| E3 ubiquitin ligase Mule ubiquitinates Miz1 and is required for TNFα-induced JNK activation Y Yang, HC Do, X Tian, C Zhang, X Liu, LA Dada, JI Sznajder, J Liu Proceedings of the National Academy of Sciences 107 (30), 13444-13449, 2010 | 64 | 2010 |
| Extracellular signal-regulated kinase (ERK) participates in the hypercapnia-induced Na, K-ATPase downregulation LC Welch, E Lecuona, A Briva, HE Trejo, LA Dada, JI Sznajder FEBS letters 584 (18), 3985-3989, 2010 | 61 | 2010 |
| Role of the small GTPase RhoA in the hypoxia-induced decrease of plasma membrane Na, K-ATPase in A549 cells LA Dada, E Novoa, E Lecuona, H Sun, JI Sznajder Journal of cell science 120 (13), 2214-2222, 2007 | 60 | 2007 |
Navdeep ChandelProfessor of Medicine, Biochemistry and Molecular Genetics, Northwestern UniversityBestätigte E-Mail-Adresse bei northwestern.edu