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Oliver Maddocks
Oliver Maddocks
Senior Research Fellow, University of Glasgow
Bestätigte E-Mail-Adresse bei glasgow.ac.uk - Startseite
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Zitiert von
Jahr
Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells
ODK Maddocks, CR Berkers, SM Mason, L Zheng, K Blyth, E Gottlieb, ...
Nature 493 (7433), 542-546, 2013
10312013
Serine is a natural ligand and allosteric activator of pyruvate kinase M2
B Chaneton, P Hillmann, L Zheng, ACL Martin, ODK Maddocks, ...
Nature 491 (7424), 458-462, 2012
6882012
A roadmap for interpreting 13C metabolite labeling patterns from cells
JM Buescher, MR Antoniewicz, LG Boros, SC Burgess, H Brunengraber, ...
Current opinion in biotechnology 34, 189-201, 2015
6642015
Serine, but not glycine, supports one-carbon metabolism and proliferation of cancer cells
CF Labuschagne, NJF Van Den Broek, GM Mackay, KH Vousden, ...
Cell reports 7 (4), 1248-1258, 2014
6042014
Modulating the therapeutic response of tumours to dietary serine and glycine starvation
ODK Maddocks, D Athineos, EC Cheung, P Lee, T Zhang, ...
Nature 544 (7650), 372-376, 2017
5782017
Metabolic regulation by p53 family members
CR Berkers, ODK Maddocks, EC Cheung, I Mor, KH Vousden
Cell metabolism 18 (5), 617-633, 2013
5062013
One-carbon metabolism in cancer
AC Newman, ODK Maddocks
British journal of cancer 116 (12), 1499-1504, 2017
4712017
Serine metabolism supports the methionine cycle and DNA/RNA methylation through de novo ATP synthesis in cancer cells
ODK Maddocks, CF Labuschagne, PD Adams, KH Vousden
Molecular cell 61 (2), 210-221, 2016
4452016
Metabolic regulation by p53
ODK Maddocks, KH Vousden
Journal of molecular medicine 89, 237-245, 2011
3982011
Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy
M Tajan, M Hennequart, EC Cheung, F Zani, AK Hock, N Legrave, ...
Nature communications 12 (1), 366, 2021
2232021
Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity
B Carroll, D Maetzel, ODK Maddocks, G Otten, M Ratcliff, GR Smith, ...
Elife 5, e11058, 2016
2192016
Attaching and effacing Escherichia coli downregulate DNA mismatch repair protein in vitro and are associated with colorectal adenocarcinomas in humans
ODK Maddocks, AJ Short, MS Donnenberg, S Bader, DJ Harrison
PloS one 4 (5), e5517, 2009
1712009
Serine one-carbon catabolism with formate overflow
J Meiser, S Tumanov, O Maddocks, CF Labuschagne, D Athineos, ...
Science advances 2 (10), e1601273, 2016
1682016
Serine and functional metabolites in cancer
AC Newman, ODK Maddocks
Trends in cell biology 27 (9), 645-657, 2017
1652017
Persistent mTORC1 signaling in cell senescence results from defects in amino acid and growth factor sensing
B Carroll, G Nelson, Y Rabanal-Ruiz, O Kucheryavenko, ...
Journal of Cell Biology 216 (7), 1949-1957, 2017
1582017
The creatine–phosphagen system is mechanoresponsive in pancreatic adenocarcinoma and fuels invasion and metastasis
V Papalazarou, T Zhang, NR Paul, A Juin, M Cantini, ODK Maddocks, ...
Nature metabolism 2 (1), 62-80, 2020
1242020
Metabolic cross-feeding in imbalanced diets allows gut microbes to improve reproduction and alter host behaviour
SF Henriques, DB Dhakan, L Serra, AP Francisco, Z Carvalho-Santos, ...
Nature communications 11 (1), 4236, 2020
1202020
A neuronal relay mediates a nutrient responsive gut/fat body axis regulating energy homeostasis in adult Drosophila
A Scopelliti, C Bauer, Y Yu, T Zhang, B Kruspig, DJ Murphy, M Vidal, ...
Cell metabolism 29 (2), 269-284. e10, 2019
982019
An Escherichia coli effector protein promotes host mutation via depletion of DNA mismatch repair proteins
ODK Maddocks, KM Scanlon, MS Donnenberg
MBio 4 (3), 10.1128/mbio. 00152-13, 2013
972013
Immune-regulated IDO1-dependent tryptophan metabolism is source of one-carbon units for pancreatic cancer and stellate cells
AC Newman, M Falcone, AH Uribe, T Zhang, D Athineos, M Pietzke, ...
Molecular Cell 81 (11), 2290-2302. e7, 2021
782021
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