| Genetics and biology of prostate cancer G Wang, D Zhao, DJ Spring, RA DePinho Genes & development 32 (17-18), 1105-1140, 2018 | 855 | 2018 |
| Acetylation targets the M2 isoform of pyruvate kinase for degradation through chaperone-mediated autophagy and promotes tumor growth L Lv, D Li, DI Zhao, R Lin, Y Chu, H Zhang, Z Zha, Y Liu, ZI Li, Y Xu, ... Molecular cell 42 (6), 719-730, 2011 | 652 | 2011 |
| The hippo tumor pathway promotes TAZ degradation by phosphorylating a phosphodegron and recruiting the SCFβ-TrCP E3 ligase CY Liu, ZY Zha, X Zhou, H Zhang, W Huang, D Zhao, T Li, SW Chan, ... Journal of Biological Chemistry 285 (48), 37159-37169, 2010 | 610 | 2010 |
| Targeting YAP-dependent MDSC infiltration impairs tumor progression G Wang, X Lu, P Dey, P Deng, CC Wu, S Jiang, Z Fang, K Zhao, ... Cancer discovery 6 (1), 80-95, 2016 | 528 | 2016 |
| KRAS-IRF2 axis drives immune suppression and immune therapy resistance in colorectal cancer W Liao, MJ Overman, AT Boutin, X Shang, DI Zhao, P Dey, J Li, G Wang, ... Cancer cell 35 (4), 559-572. e7, 2019 | 523 | 2019 |
| Lysine-5 acetylation negatively regulates lactate dehydrogenase A and is decreased in pancreatic cancer D Zhao, SW Zou, Y Liu, X Zhou, Y Mo, P Wang, YH Xu, B Dong, Y Xiong, ... Cancer cell 23 (4), 464-476, 2013 | 349 | 2013 |
| Mitogenic and oncogenic stimulation of K433 acetylation promotes PKM2 protein kinase activity and nuclear localization L Lv, YP Xu, D Zhao, FL Li, W Wang, N Sasaki, Y Jiang, X Zhou, TT Li, ... Molecular cell 52 (3), 340-352, 2013 | 313 | 2013 |
| Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer P Dey, J Baddour, F Muller, CC Wu, H Wang, WT Liao, Z Lan, A Chen, ... Nature 542 (7639), 119-123, 2017 | 281 | 2017 |
| Symbiotic macrophage-glioma cell interactions reveal synthetic lethality in PTEN-null glioma P Chen, D Zhao, J Li, X Liang, J Li, A Chang, VK Henry, Z Lan, DJ Spring, ... Cancer cell 35 (6), 868-884. e6, 2019 | 280 | 2019 |
| Synthetic essentiality of chromatin remodelling factor CHD1 in PTEN-deficient cancer D Zhao, X Lu, G Wang, Z Lan, W Liao, J Li, X Liang, JR Chen, S Shah, ... Nature 542 (7642), 484-488, 2017 | 211 | 2017 |
| NOTCH-induced aldehyde dehydrogenase 1A1 deacetylation promotes breast cancer stem cells D Zhao, Y Mo, MT Li, SW Zou, ZL Cheng, YP Sun, Y Xiong, KL Guan, ... The Journal of clinical investigation 124 (12), 5453-5465, 2014 | 176 | 2014 |
| Targeting YAP-dependent MDSC infiltration impairs tumor progression. Cancer Discov. 2016; 6: 80–95. doi: 10.1158/2159-8290 G Wang, X Lu, P Dey, P Deng, CC Wu, S Jiang, Z Fang, K Zhao, ... CD-15-0224.[Europe PMC free article][Abstract][CrossRef][Academic Search], 0 | 98 | |
| Glucocorticoid receptor regulates PD-L1 and MHC-I in pancreatic cancer cells to promote immune evasion and immunotherapy resistance Y Deng, X Xia, Y Zhao, Z Zhao, C Martinez, W Yin, J Yao, Q Hang, W Wu, ... Nature communications 12 (1), 7041, 2021 | 91 | 2021 |
| Chromatin regulator CHD1 remodels the immunosuppressive tumor microenvironment in PTEN-deficient prostate cancer D Zhao, L Cai, X Lu, X Liang, J Li, P Chen, M Ittmann, X Shang, S Jiang, ... Cancer discovery 10 (9), 1374-1387, 2020 | 79 | 2020 |
| Telomere dysfunction activates YAP1 to drive tissue inflammation D Chakravarti, B Hu, X Mao, A Rashid, J Li, J Li, W Liao, EM Whitley, ... Nature communications 11 (1), 4766, 2020 | 71 | 2020 |
| Synthetic Essentiality of Tryptophan 2,3-Dioxygenase 2 in APC-Mutated Colorectal Cancer R Lee, J Li, J Li, CJ Wu, S Jiang, WH Hsu, D Chakravarti, P Chen, ... Cancer discovery 12 (7), 1702-1717, 2022 | 39 | 2022 |
| Acetylation control of cancer cell metabolism R Lin, X Zhou, W Huang, D Zhao, L Lv, Y Xiong, KL Guan, QY Lei Current pharmaceutical design 20 (15), 2627-2633, 2014 | 38 | 2014 |
| LDH-A acetylation: implication in cancer D Zhao, Y Xiong, QY Lei, KL Guan Oncotarget 4 (6), 802, 2013 | 31 | 2013 |
| Immune checkpoint B7-H3 is a therapeutic vulnerability in prostate cancer harboring PTEN and TP53 deficiencies W Shi, Y Wang, Y Zhao, JJ Kim, H Li, C Meng, F Chen, J Zhang, DH Mak, ... Science translational medicine 15 (695), eadf6724, 2023 | 30 | 2023 |
| Synthetic essentiality: Targeting tumor suppressor deficiencies in cancer D Zhao, RA DePinho Bioessays 39 (8), 1700076, 2017 | 29 | 2017 |