Metabolic inhibition induces opening of unapposed connexin 43 gap junction hemichannels and reduces gap junctional communication in cortical astrocytes in culture JE Contreras, HA Sánchez, EA Eugenín, D Speidel, M Theis, K Willecke, ... Proceedings of the National Academy of Sciences 99 (1), 495-500, 2002 | 657 | 2002 |
Gating and regulation of connexin 43 (Cx43) hemichannels JE Contreras, JC Sáez, FF Bukauskas, MVL Bennett Proceedings of the National Academy of Sciences 100 (20), 11388-11393, 2003 | 527 | 2003 |
New roles for astrocytes: gap junction hemichannels have something to communicate MVL Bennett, JE Contreras, FF Bukauskas, JC Sáez Trends in neurosciences 26 (11), 610-617, 2003 | 497 | 2003 |
Role of connexin-based gap junction channels and hemichannels in ischemia-induced cell death in nervous tissue JE Contreras, HA Sánchez, LP Véliz, FF Bukauskas, MVL Bennett, ... Brain Research Reviews 47 (1-3), 290-303, 2004 | 312 | 2004 |
Hepatitis E virus ORF3 is a functional ion channel required for release of infectious particles Q Ding, B Heller, JMV Capuccino, B Song, I Nimgaonkar, G Hrebikova, ... Proceedings of the National Academy of Sciences 114 (5), 1147-1152, 2017 | 245 | 2017 |
Gap junctions, homeostasis, and injury A De Maio, VL Vega, JE Contreras Journal of cellular physiology 191 (3), 269-282, 2002 | 195 | 2002 |
Gap junction hemichannels in astrocytes of the CNS JC Sáez, JE Contreras, FF Bukauskas, MA Retamal, MVL Bennett Acta physiologica scandinavica 179 (1), 9-22, 2003 | 188 | 2003 |
Mechanism of gating by calcium in connexin hemichannels W Lopez, J Ramachandran, A Alsamarah, Y Luo, AL Harris, JE Contreras Proceedings of the National Academy of Sciences 113 (49), E7986-E7995, 2016 | 112 | 2016 |
Keratitis-ichthyosis-deafness syndrome-associated Cx26 mutants produce nonfunctional gap junctions but hyperactive hemichannels when co-expressed with wild type Cx43 IE García, J Maripillán, O Jara, R Ceriani, A Palacios-Munoz, ... Journal of Investigative Dermatology 135 (5), 1338-1347, 2015 | 97 | 2015 |
Gating at the selectivity filter in cyclic nucleotide-gated channels JE Contreras, D Srikumar, M Holmgren Proceedings of the National Academy of Sciences 105 (9), 3310-3314, 2008 | 87 | 2008 |
ATP and large signaling metabolites flux through caspase-activated Pannexin 1 channels AK Narahari, AJB Kreutzberger, PS Gaete, YH Chiu, SA Leonhardt, ... Elife 10, e64787, 2021 | 78 | 2021 |
Selective connexin43 inhibition prevents isoproterenol-induced arrhythmias and lethality in muscular dystrophy mice JP Gonzalez, J Ramachandran, LH Xie, JE Contreras, D Fraidenraich Scientific reports 5 (1), 13490, 2015 | 78 | 2015 |
Prevention of connexin-43 remodeling protects against Duchenne muscular dystrophy cardiomyopathy E Himelman, MA Lillo, J Nouet, JP Gonzalez, Q Zhao, LH Xie, H Li, T Liu, ... The Journal of clinical investigation 130 (4), 1713-1727, 2020 | 70 | 2020 |
State-dependent FRET reports calcium-and voltage-dependent gating-ring motions in BK channels P Miranda, JE Contreras, AJR Plested, FJ Sigworth, M Holmgren, ... Proceedings of the National Academy of Sciences 110 (13), 5217-5222, 2013 | 64 | 2013 |
Activation of human polymorphonuclear cells induces formation of functional gap junctions and expression of connexins M Brañes, JC Sáez | 63 | 2002 |
S-nitrosylation of connexin43 hemichannels elicits cardiac stress–induced arrhythmias in Duchenne muscular dystrophy mice MA Lillo, E Himelman, N Shirokova, LH Xie, D Fraidenraich, JE Contreras JCI insight 4 (24), 2019 | 60 | 2019 |
Insights on the mechanisms of Ca2+ regulation of connexin26 hemichannels revealed by human pathogenic mutations (D50N/Y) W Lopez, J Gonzalez, Y Liu, AL Harris, JE Contreras Journal of General Physiology 142 (1), 23-35, 2013 | 60 | 2013 |
Functioning of cx43 hemichannels demonstrated by single channel properties JE Contreras, JC Sáez, FF Bukauskas, MVL Bennett Cell communication & adhesion 10 (4-6), 245-249, 2003 | 54 | 2003 |
Cx43 hemichannels contribute to astrocyte-mediated toxicity in sporadic and familial ALS AA Almad, A Taga, J Joseph, SK Gross, C Welsh, A Patankar, JP Richard, ... Proceedings of the National Academy of Sciences 119 (13), e2107391119, 2022 | 53 | 2022 |
Effect of carbide precipitation on the structure and hardness in the heat-affected zone of Hadfield steel after post-cooling treatments E Curiel-Reyna, J Contreras, T Rangel-Ortis, A Herrera, L Baños, A Real, ... Materials and Manufacturing Processes 23 (1), 14-20, 2007 | 46 | 2007 |