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| Epigenomic alterations define lethal CIMP-positive ependymomas of infancy SC Mack, H Witt, RM Piro, L Gu, S Zuyderduyn, AM Stütz, X Wang, ... Nature 506 (7489), 445-450, 2014 | 671 | 2014 |
| Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma PA Northcott, Y Nakahara, X Wu, L Feuk, DW Ellison, S Croul, S Mack, ... Nature genetics 41 (4), 465-472, 2009 | 505 | 2009 |
| Clonal selection drives genetic divergence of metastatic medulloblastoma X Wu, PA Northcott, A Dubuc, AJ Dupuy, DJH Shih, H Witt, S Croul, ... Nature 482 (7386), 529-533, 2012 | 493 | 2012 |
| The eEF2 kinase confers resistance to nutrient deprivation by blocking translation elongation G Leprivier, M Remke, B Rotblat, A Dubuc, ARF Mateo, M Kool, ... Cell 153 (5), 1064-1079, 2013 | 456 | 2013 |
| Rapid, reliable, and reproducible molecular sub-grouping of clinical medulloblastoma samples PA Northcott, DJH Shih, M Remke, YJ Cho, M Kool, C Hawkins, ... Acta neuropathologica 123, 615-626, 2012 | 441 | 2012 |
| Recurrence patterns across medulloblastoma subgroups: an integrated clinical and molecular analysis V Ramaswamy, M Remke, E Bouffet, CC Faria, S Perreault, YJ Cho, ... The lancet oncology 14 (12), 1200-1207, 2013 | 421 | 2013 |
| Institutional implementation of clinical tumor profiling on an unselected cancer population LM Sholl, K Do, P Shivdasani, E Cerami, AM Dubuc, FC Kuo, EP Garcia, ... JCI insight 1 (19), 2016 | 402 | 2016 |
| Clonal evolution in patients with chronic lymphocytic leukaemia developing resistance to BTK inhibition JA Burger, DA Landau, A Taylor-Weiner, I Bozic, H Zhang, K Sarosiek, ... Nature communications 7 (1), 11589, 2016 | 399 | 2016 |
| Cytogenetic prognostication within medulloblastoma subgroups DJH Shih, PA Northcott, M Remke, A Korshunov, V Ramaswamy, M Kool, ... Journal of clinical oncology 32 (9), 886-896, 2014 | 373 | 2014 |
| Pediatric and adult sonic hedgehog medulloblastomas are clinically and molecularly distinct PA Northcott, T Hielscher, A Dubuc, S Mack, D Shih, M Remke, ... Acta neuropathologica 122, 231-240, 2011 | 289 | 2011 |
| Molecular subgroups of medulloblastoma PA Northcott, AM Dubuc, S Pfister, MD Taylor Expert review of neurotherapeutics 12 (7), 871-884, 2012 | 214 | 2012 |
| TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma M Remke, V Ramaswamy, J Peacock, DJH Shih, C Koelsche, ... Acta neuropathologica 126, 917-929, 2013 | 205 | 2013 |
| Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma AM Dubuc, M Remke, A Korshunov, PA Northcott, SH Zhan, ... Acta neuropathologica 125, 373-384, 2013 | 195 | 2013 |
| Standards for the classification of pathogenicity of somatic variants in cancer (oncogenicity): Joint recommendations of Clinical Genome Resource (ClinGen), Cancer Genomics … P Horak, M Griffith, AM Danos, BA Pitel, S Madhavan, X Liu, C Chow, ... Genetics in Medicine 24 (5), 986-998, 2022 | 162 | 2022 |
| A molecularly integrated grade for meningioma J Driver, SE Hoffman, S Tavakol, E Woodward, EA Maury, V Bhave, ... Neuro-oncology 24 (5), 796-808, 2022 | 160 | 2022 |
| MicroRNA 218 acts as a tumor suppressor by targeting multiple cancer phenotype-associated genes in medulloblastoma S Venkataraman, DK Birks, I Balakrishnan, I Alimova, PS Harris, PR Patel, ... Journal of Biological Chemistry 288 (3), 1918-1928, 2013 | 126 | 2013 |
| Polo-like kinase 1 (PLK1) inhibition suppresses cell growth and enhances radiation sensitivity in medulloblastoma cells PS Harris, S Venkataraman, I Alimova, DK Birks, AM Donson, J Knipstein, ... BMC cancer 12, 1-13, 2012 | 107 | 2012 |
| Medulloblastoma subgroups remain stable across primary and metastatic compartments X Wang, AM Dubuc, V Ramaswamy, S Mack, DMA Gendoo, M Remke, ... Acta neuropathologica 129, 449-457, 2015 | 102 | 2015 |
| The current state of clinical interpretation of sequence variants DC Hoskinson, AM Dubuc, H Mason-Suares Current opinion in genetics & development 42, 33-39, 2017 | 101 | 2017 |
