| Phosphodiesterase-5 inhibitor sildenafil preconditions adult cardiac myocytes against necrosis and apoptosis: essential role of nitric oxide signaling A Das, L Xi, RC Kukreja Journal of Biological Chemistry 280 (13), 12944-12955, 2005 | 472 | 2005 |
| Sildenafil induces delayed preconditioning through inducible nitric oxide synthase–dependent pathway in mouse heart F Salloum, C Yin, L Xi, RC Kukreja Circulation Research 92 (6), 595-597, 2003 | 317 | 2003 |
| Pharmacological preconditioning with sildenafil: basic mechanisms and clinical implications RC Kukreja, F Salloum, A Das, R Ockaili, C Yin, YA Bremer, PW Fisher, ... Vascular pharmacology 42 (5-6), 219-232, 2005 | 262 | 2005 |
| PDE5 inhibitors as therapeutics for heart disease, diabetes and cancer A Das, D Durrant, FN Salloum, L Xi, RC Kukreja Pharmacology & therapeutics 147, 12-21, 2015 | 252 | 2015 |
| Protein kinase G-dependent cardioprotective mechanism of phosphodiesterase-5 inhibition involves phosphorylation of ERK and GSK3β∗ A Das, L Xi, RC Kukreja Journal of Biological Chemistry 283 (43), 29572-29585, 2008 | 236 | 2008 |
| Hypoxia inducible factor 1 (HIF-1) and cardioprotection D Tekin, AD Dursun, L Xi Acta Pharmacologica Sinica 31 (9), 1085-1094, 2010 | 230 | 2010 |
| Rapamycin confers preconditioning-like protection against ischemia–reperfusion injury in isolated mouse heart and cardiomyocytes SA Khan, F Salloum, A Das, L Xi, GW Vetrovec, RC Kukreja Journal of molecular and cellular cardiology 41 (2), 256-264, 2006 | 225 | 2006 |
| Hypoxia, HIF-1α, and COVID-19: from pathogenic factors to potential therapeutic targets ZO Serebrovska, EY Chong, TV Serebrovska, LV Tumanovska, L Xi Acta Pharmacologica Sinica 41 (12), 1539-1546, 2020 | 218 | 2020 |
| Inducible Nitric Oxide Synthase Mediates Delayed Myocardial Protection Induced by Activation of Adenosine A1 Receptors: Evidence From Gene-Knockout Mice T Zhao, L Xi, J Chelliah, JE Levasseur, RC Kukreja Circulation 102 (8), 902-907, 2000 | 212 | 2000 |
| Cardioprotection with phosphodiesterase-5 inhibition—a novel preconditioning strategy RC Kukreja, R Ockaili, F Salloum, C Yin, J Hawkins, A Das, L Xi Journal of molecular and cellular cardiology 36 (2), 165-173, 2004 | 202 | 2004 |
| Cobalt chloride induces delayed cardiac preconditioning in mice through selective activation of HIF-1α and AP-1 and iNOS signaling L Xi, M Taher, C Yin, F Salloum, RC Kukreja American Journal of Physiology-Heart and Circulatory Physiology 287 (6 …, 2004 | 186 | 2004 |
| ERK phosphorylation mediates sildenafil-induced myocardial protection against ischemia-reperfusion injury in mice A Das, FN Salloum, L Xi, YJ Rao, RC Kukreja American journal of physiology-heart and circulatory physiology 296 (5 …, 2009 | 182 | 2009 |
| Mammalian target of rapamycin (mTOR) inhibition with rapamycin improves cardiac function in type 2 diabetic mice: potential role of attenuated oxidative stress and altered … A Das, D Durrant, S Koka, FN Salloum, L Xi, RC Kukreja Journal of Biological Chemistry 289 (7), 4145-4160, 2014 | 174 | 2014 |
| Essential role of inducible nitric oxide synthase in monophosphoryl lipid A–induced late cardioprotection: evidence from pharmacological inhibition and gene knockout mice L Xi, NC Jarrett, ML Hess, RC Kukreja Circulation 99 (16), 2157-2163, 1999 | 161 | 1999 |
| Long-acting phosphodiesterase-5 inhibitor tadalafil attenuates doxorubicin-induced cardiomyopathy without interfering with chemotherapeutic effect S Koka, A Das, SG Zhu, D Durrant, L Xi, RC Kukreja Journal of Pharmacology and Experimental Therapeutics 334 (3), 1023-1030, 2010 | 134 | 2010 |
| Intermittent hypoxia training as non-pharmacologic therapy for cardiovascular diseases: Practical analysis on methods and equipment TV Serebrovskaya, L Xi Experimental Biology and Medicine 241 (15), 1708-1723, 2016 | 121 | 2016 |
| Dietary nitrate supplementation protects against doxorubicin-induced cardiomyopathy by improving mitochondrial function SG Zhu, RC Kukreja, A Das, Q Chen, EJ Lesnefsky, L Xi Journal of the American College of Cardiology 57 (21), 2181-2189, 2011 | 121 | 2011 |
| Evidence that NOS2 acts as a trigger and mediator of late preconditioning induced by acute systemic hypoxia L Xi, D Tekin, E Gursoy, F Salloum, JE Levasseur, RC Kukreja American Journal of Physiology-Heart and Circulatory Physiology 283 (1), H5-H12, 2002 | 115 | 2002 |
| Inosine and hypoxanthine as novel biomarkers for cardiac ischemia: from bench to point-of-care DE Farthing, CA Farthing, L Xi Experimental Biology and Medicine 240 (6), 821-831, 2015 | 109 | 2015 |
| Chronic inhibition of phosphodiesterase 5 with tadalafil attenuates mitochondrial dysfunction in type 2 diabetic hearts: potential role of NO/SIRT1/PGC-1α signaling S Koka, HS Aluri, L Xi, EJ Lesnefsky, RC Kukreja American Journal of Physiology-Heart and Circulatory Physiology 306 (11 …, 2014 | 107 | 2014 |
Rakesh KukrejaVirginia Commonwealth UniversityBestätigte E-Mail-Adresse bei vcu.edu
