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Christopher M. Hickey
Christopher M. Hickey
Arvinas
Bestätigte E-Mail-Adresse bei arvinas.com
Titel
Zitiert von
Zitiert von
Jahr
Function and regulation of SUMO proteases
CM Hickey, NR Wilson, M Hochstrasser
Nature reviews Molecular cell biology 13 (12), 755-766, 2012
7092012
Controlling gene expression in mycobacteria with anhydrotetracycline and Tet repressor
S Ehrt, XV Guo, CM Hickey, M Ryou, M Monteleone, LW Riley, ...
Nucleic acids research 33 (2), e21-e21, 2005
4402005
Reconstituted membrane fusion requires regulatory lipids, SNAREs and synergistic SNARE chaperones
J Mima, CM Hickey, H Xu, Y Jun, W Wickner
The EMBO Journal 27 (15), 2031-2042, 2008
1992008
HOPS initiates vacuole docking by tethering membranes before trans-SNARE complex assembly
CM Hickey, W Wickner
Molecular biology of the cell 21 (13), 2297-2305, 2010
1502010
HOPS proofreads the trans-SNARE complex for yeast vacuole fusion
VJ Starai, CM Hickey, W Wickner
Molecular biology of the cell 19 (6), 2500-2508, 2008
1472008
Expression of many immunologically important genes in Mycobacterium tuberculosis-infected macrophages is independent of both TLR2 and TLR4 but dependent on IFN-αβ receptor and …
S Shi, A Blumenthal, CM Hickey, S Gandotra, D Levy, S Ehrt
The Journal of Immunology 175 (5), 3318-3328, 2005
1402005
Minimal membrane docking requirements revealed by reconstitution of Rab GTPase-dependent membrane fusion from purified components
C Stroupe, CM Hickey, J Mima, AS Burfeind, W Wickner
Proceedings of the National Academy of Sciences 106 (42), 17626-17633, 2009
1232009
The major role of the Rab Ypt7p in vacuole fusion is supporting HOPS membrane association
CM Hickey, C Stroupe, W Wickner
Journal of Biological Chemistry 284 (24), 16118-16125, 2009
892009
Stringent 3Q· 1R Composition of the SNARE 0-Layer Can Be Bypassed for Fusion by Compensatory SNARE Mutation or by Lipid Bilayer Modification
RA Fratti, KM Collins, CM Hickey, W Wickner
Journal of Biological Chemistry 282 (20), 14861-14867, 2007
602007
SUMO Pathway Modulation of Regulatory Protein Binding at the Ribosomal DNA Locus in Saccharomyces cerevisiae
J Gillies, CM Hickey, D Su, Z Wu, J Peng, M Hochstrasser
Genetics 202 (4), 1377-1394, 2016
372016
Evidence for expression of a single distinct form of mammalian cysteine dioxygenase
MH Stipanuk, M Londono, LL Hirschberger, C Hickey, DJ Thiel, L Wang
Amino acids 26, 99-106, 2004
332004
Co-opting the E3 ligase KLHDC2 for targeted protein degradation by small molecules
CM Hickey, KM Digianantonio, K Zimmermann, A Harbin, C Quinn, ...
Nature Structural & Molecular Biology, 1-12, 2024
252024
Protein quality control degron-containing substrates are differentially targeted in the cytoplasm and nucleus by ubiquitin ligases
CM Hickey, C Breckel, M Zhang, WC Theune, M Hochstrasser
Genetics 217 (1), 1-19, 2021
242021
STUbL-mediated degradation of the transcription factor MATα2 requires degradation elements that coincide with corepressor binding sites
CM Hickey, M Hochstrasser
Molecular Biology of the Cell 26 (19), 3401-3412, 2015
232015
DNA binding by the MATα2 transcription factor controls its access to alternative ubiquitin-modification pathways
CM Hickey, Y Xie, M Hochstrasser
Molecular biology of the cell 29 (5), 542-556, 2018
202018
The Sts1 nuclear import adapter uses a non-canonical bipartite nuclear localization signal and is directly degraded by the proteasome
L Budenholzer, C Breckel, CM Hickey, M Hochstrasser
Journal of Cell Science 133 (6), 2020
152020
Degradation elements coincide with cofactor binding sites in a short-lived transcription factor
CM Hickey
Cellular logistics 6 (1), e1157664, 2016
102016
Yeast 26S proteasome nuclear import is coupled to nucleus-specific degradation of the karyopherin adaptor protein Sts1
CA Breckel, ZM Johnson, CM Hickey, M Hochstrasser
Scientific Reports 14 (1), 2048, 2024
22024
Targeted Protein Degradation: Methods and Protocols
AM Cacace, CM Hickey, M Békés
Humana Press, 2021
22021
New therapies on the horizon: Targeted protein degradation in neuroscience
JA Gregory, CM Hickey, J Chavez, AM Cacace
Cell Chemical Biology 31 (9), 1688-1698, 2024
12024
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