MICU1 interacts with the D-ring of the MCU pore to control its Ca2+ flux and sensitivity to Ru360 M Paillard, G Csordás, KT Huang, P Várnai, SK Joseph, G Hajnóczky Molecular cell 72 (4), 778-785. e3, 2018 | 122 | 2018 |
Cardioprotection by the mitochondrial unfolded protein response requires ATF5 YT Wang, Y Lim, MN McCall, KT Huang, CM Haynes, K Nehrke, ... American Journal of Physiology-Heart and Circulatory Physiology 317 (2 …, 2019 | 117 | 2019 |
Dysregulation of mitochondrial Ca2+ uptake and sarcolemma repair underlie muscle weakness and wasting in patients and mice lacking MICU1 V Debattisti, A Horn, R Singh, EL Seifert, MW Hogarth, DA Mazala, ... Cell reports 29 (5), 1274-1286. e6, 2019 | 96 | 2019 |
MICU1 confers protection from MCU-dependent manganese toxicity J Wettmarshausen, V Goh, KT Huang, DM Arduino, U Tripathi, A Leimpek, ... Cell Reports 25 (6), 1425-1435. e7, 2018 | 30 | 2018 |
Highly localized intracellular Ca2+ signals promote optimal salivary gland fluid secretion T Takano, AM Wahl, KT Huang, T Narita, J Rugis, J Sneyd, DI Yule Elife 10, e66170, 2021 | 24 | 2021 |
Molecular pathophysiology of human MICU1 deficiency N Kohlschmidt, M Elbracht, A Czech, M Häusler, V Phan, A Töpf, ... Neuropathology and Applied Neurobiology 47 (6), 840-855, 2021 | 23 | 2021 |
Vesicular transport mediates the uptake of cytoplasmic proteins into mitochondria in Drosophila melanogaster PL Chen, KT Huang, CY Cheng, JC Li, HY Chan, TY Lin, MP Su, ... Nature Communications 11 (1), 2592, 2020 | 23 | 2020 |
Altered composition of the mitochondrial Ca2+ uniporter in the failing human heart M Paillard, KT Huang, D Weaver, JP Lambert, JW Elrod, G Hajnóczky Cell Calcium 105, 102618, 2022 | 21 | 2022 |
MICU1 controls the sensitivity of the mitochondrial Ca2+ uniporter to activators and inhibitors M Rodríguez-Prados, KT Huang, K Márta, M Paillard, G Csordás, ... Cell Chemical Biology 30 (6), 606-617. e4, 2023 | 7 | 2023 |
Loss of STIM1 and STIM2 in salivary glands disrupts ANO1 function but does not induce Sjogren's disease GY Son, A Zou, A Wahl, KT Huang, S Zorgit, M Vinu, F Zhou, L Wagner, ... Function, zqae047, 2024 | 2 | 2024 |
The characteristics of intracellular Ca2+ signals in vivo necessitate a new model for salivary fluid secretion T Takano, AM Wahl, KT Huang, J Rugis, J Sneyd, DI Yule bioRxiv, 2020.12. 30.424864, 2021 | 2 | 2021 |
Dysregulated Ca2+ signaling, fluid secretion, and mitochondrial function in a mouse model of early Sjögren’s syndrome KT Huang, LE Wagner, T Takano, XX Lin, H Bagavant, U Deshmukh, ... bioRxiv, 2024 | 1 | 2024 |
Mitochondrial membrane potential regulates nuclear DNA methylation and gene expression through phospholipid remodeling MP Mori, O Lozoya, AM Brooks, D Grenet, CA Nadalutti, B Ryback, ... bioRxiv, 2024 | 1 | 2024 |
Mitochondria and the epigenome: how we get there, what are the outcomes MP Mori, O Lozoya, AM Brooks, D Grenet, CA Nadalutti, A Jarmusch, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1870 (8), 167363, 2024 | | 2024 |
The Function of MICU2 in Mitochondrial Calcium Uniport KT Huang, M Paillard, P Varnai, G Hajnoczky Biophysical Journal 114 (3), 119a, 2018 | | 2018 |
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