Potential impact of the multi-target drug approach in the treatment of some complex diseases XH Makhoba, C Viegas Jr, RA Mosa, FPD Viegas, OJ Pooe Drug design, development and therapy, 3235-3249, 2020 | 209 | 2020 |
Plasmodium falciparum Hop (PfHop) Interacts with the Hsp70 Chaperone in a Nucleotide-Dependent Fashion and Exhibits Ligand Selectivity AS Tawanda Zininga, Stanely Makumire, Grace Wairimu Gitau, James M. Njunge ... PLoS ONE 10 (8), e0135326, 2015 | 57 | 2015 |
Design and synthesis of quinoline-pyrimidine inspired hybrids as potential plasmodial inhibitors F Kayamba, T Malimabe, IK Ademola, OJ Pooe, ND Kushwaha, ... European Journal of Medicinal Chemistry 217, 113330, 2021 | 48 | 2021 |
Polymyxin B inhibits the chaperone activity of Plasmodium falciparum Hsp70 T Zininga, OJ Pooe, PB Makhado, L Ramatsui, E Prinsloo, I Achilonu, ... Cell Stress and Chaperones, 1-9, 2017 | 46 | 2017 |
Biological role of chalcones in medicinal chemistry S Tekale, S Mashele, O Pooe, S Thore, P Kendrekar, R Pawar Vector-borne diseases-recent developments in epidemiology and control, 1-18, 2020 | 43 | 2020 |
Plant-based production of highly potent anti-HiV antibodies with engineered posttranslational modifications AA Singh, O Pooe, L Kwezi, T Lotter-Stark, SH Stoychev, K Alexandra, ... Scientific reports 10 (1), 1-9, 2020 | 32 | 2020 |
Lactate dehydrogenase and malate dehydrogenase: Potential antiparasitic targets for drug development studies F Kayamba, M Faya, OJ Pooe, B Kushwaha, ND Kushwaha, VA Obakachi, ... Bioorganic & Medicinal Chemistry 50, 116458, 2021 | 30 | 2021 |
Oxidative testicular injury: effect of l-leucine on redox, cholinergic and purinergic dysfunctions, and dysregulated metabolic pathways OL Erukainure, O Atolani, P Banerjee, R Abel, OJ Pooe, OS Adeyemi, ... Amino Acids 53, 359-380, 2021 | 30 | 2021 |
Iso-Mukaadial Acetate from Warburgia salutaris Enhances Glucose Uptake in the L6 Rat Myoblast Cell Line NZ Msomi, FO Shode, OJ Pooe, S Mazibuko-Mbeje, MBC Simelane Biomolecules 9 (10), 520, 2019 | 27 | 2019 |
Reverse vaccinology approach to design a multi-epitope vaccine construct based on the Mycobacterium tuberculosis biomarker PE_PGRS17 A Moodley, A Fatoba, M Okpeku, T Emmanuel Chiliza, ... Immunologic research 70 (4), 501-517, 2022 | 24 | 2022 |
Plasmodium falciparum heat shock protein 70 lacks immune modulatory activity OJ Pooe, G Kollisch, H Heine, A Shonhai Protein and peptide letters 24 (6), 503-510, 2017 | 22 | 2017 |
Evaluating Iso-Mukaadial Acetate and Ursolic Acid Acetate as Plasmodium falciparum Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase Inhibitors F Opoku, PP Govender, OJ Pooe, MBC Simelane Biomolecules 9 (12), 861, 2019 | 20 | 2019 |
Characterization and Biological Evaluation of Zinc Oxide Nanoparticles Synthesized from Pleurotus ostreatus Mushroom SS Mkhize, OJ Pooe, S Khoza, IN Mongalo, R Khan, MBC Simelane Applied Sciences 12 (17), 8563, 2022 | 19 | 2022 |
Protein PEGylation: navigating recombinant protein stability, aggregation, and bioactivity LK Zuma, NL Gasa, XH Makhoba, OJ Pooe BioMed Research International 2022 (1), 8929715, 2022 | 19 | 2022 |
The Effect of Supplementing Mushroom Growing Substrates on the Bioactive Compounds, Antimicrobial Activity, and Antioxidant Activity of Pleurotus ostreatus SS Mkhize, MB Cedric Simelane, IN Mongalo, OJ Pooe Biochemistry Research International 2022 (1), 9436614, 2022 | 18 | 2022 |
Cytotoxic and Antioxidant Activities of Selected South African Medicinal Plants G Ayeni, OJ Pooe, M Singh, N Nundkumar, MBC Simelane Pharmacognosy Journal 11 (6), Suppl:1532-1539, 2019 | 18 | 2019 |
Antimicrobial Resistance of Neisseria gonorrhoeae in Sub-Saharan Populations SH Yakobi, OJ Pooe Bacteria 1 (2), 96-111, 2022 | 17 | 2022 |
Screening of antimicrobial properties and bioactive compounds of Pleurotus ostreatus extracts against Staphylococcus aureus, Escherichia coli, and Neisseria gonorrhoeae SH Yakobi, S Mkhize, OJ Pooe Biochemistry Research International 2023 (1), 1777039, 2023 | 13 | 2023 |
Iso-mukaadial acetate and ursolic acid acetate inhibit the chaperone activity of Plasmodium falciparum heat shock protein 70-1 N Salomane, OJ Pooe, MBC Simelane Cell Stress and Chaperones 26 (4), 685-693, 2021 | 11 | 2021 |
Molecular Chaperone Assisted Expression Systems: Obtaining Pure Soluble and Active Recombinant Proteins for Structural and Therapeutic Purposes XH Makhoba, OJ Pooe, MS Mthembu Journal of Proteomics & Bioinformatics 8, 212-216, 2015 | 11 | 2015 |