| A cellular hierarchy framework for understanding heterogeneity and predicting drug response in acute myeloid leukemia AGX Zeng, S Bansal, L Jin, A Mitchell, WC Chen, HA Abbas, ... Nature medicine 28 (6), 1212-1223, 2022 | 201 | 2022 |
| Enhancer Hijacking Drives Oncogenic BCL11B Expression in Lineage-Ambiguous Stem Cell Leukemia LE Montefiori, S Bendig, Z Gu, X Chen, P Pölönen, X Ma, A Murison, ... Cancer discovery 11 (11), 2846-2867, 2021 | 144 | 2021 |
| Sphingolipid modulation activates proteostasis programs to govern human hematopoietic stem cell self-renewal SZ Xie, L Garcia-Prat, V Voisin, R Ferrari, OI Gan, E Wagenblast, ... Cell stem cell 25 (5), 639-653. e7, 2019 | 105 | 2019 |
| TFEB-mediated endolysosomal activity controls human hematopoietic stem cell fate L García-Prat, KB Kaufmann, F Schneiter, V Voisin, A Murison, J Chen, ... Cell stem cell 28 (10), 1838-1850. e10, 2021 | 103 | 2021 |
| Sphingosine-1-phosphate receptor 3 potentiates inflammatory programs in normal and leukemia stem cells to promote differentiation SZ Xie, KB Kaufmann, W Wang, M Chan-Seng-Yue, OI Gan, E Laurenti, ... Blood cancer discovery 2 (1), 32-53, 2021 | 49 | 2021 |
| A latent subset of human hematopoietic stem cells resists regenerative stress to preserve stemness KB Kaufmann, AGX Zeng, E Coyaud, L Garcia-Prat, E Papalexi, ... Nature immunology 22 (6), 723-734, 2021 | 47 | 2021 |
| Identification and characterization of in vitro expanded hematopoietic stem cells JLC Che, D Bode, I Kucinski, AH Cull, F Bain, HJ Becker, M Jassinskaja, ... EMBO reports 23 (10), e55502, 2022 | 36 | 2022 |
| Transcriptomic classes of BCR-ABL1 lymphoblastic leukemia JC Kim, M Chan-Seng-Yue, S Ge, AGX Zeng, K Ng, OI Gan, L Garcia-Prat, ... Nature genetics 55 (7), 1186-1197, 2023 | 32 | 2023 |
| Selective advantage of mutant stem cells in human clonal hematopoiesis is associated with attenuated response to inflammation and aging NA Jakobsen*, S Turkalj*, AGX Zeng*, B Stoilova, M Metzner, S Rahmig, ... Cell Stem Cell, 2024 | 23 | 2024 |
| Simultaneous inhibition of Sirtuin 3 and cholesterol homeostasis targets acute myeloid leukemia stem cells by perturbing fatty acid β-oxidation and inducing lipotoxicity C O’Brien, T Ling, JM Berman, R Culp-Hill, JA Reisz, V Rondeau, ... Haematologica 108 (9), 2343, 2023 | 21 | 2023 |
| Precise single-cell transcriptomic mapping of normal and leukemic cell states reveals unconventional lineage priming in acute myeloid leukemia AGX Zeng, I Iacobucci, S Shah, A Mitchell, G Wong, S Bansal, Q Gao, ... bioRxiv, 2023 | 13 | 2023 |
| Single cell dissection of developmental origins and transcriptional heterogeneity in B-cell acute lymphoblastic leukemia I Iacobucci, AGX Zeng, Q Gao, L Garcia-Prat, P Baviskar, S Shah, ... bioRxiv, 2023.12. 04.569954, 2023 | 12 | 2023 |
| KDM6 demethylases integrate DNA repair gene regulation and loss of KDM6A sensitizes human acute myeloid leukemia to PARP and BCL2 inhibition LD Boila, S Ghosh, SK Bandyopadhyay, L Jin, A Murison, AGX Zeng, ... Leukemia 37 (4), 751-764, 2023 | 12 | 2023 |
| Integration of intra-sample contextual error modeling for improved detection of somatic mutations from deep sequencing S Abelson, AGX Zeng, I Nofech-Mozes, TT Wang, SWK Ng, MD Minden, ... Science advances 6 (50), eabe3722, 2020 | 11 | 2020 |
| Identification of the global miR-130a targetome reveals a role for TBL1XR1 in hematopoietic stem cell self-renewal and t (8; 21) AML G Krivdova, V Voisin, EM Schoof, SA Marhon, A Murison, JL McLeod, ... Cell reports 38 (10), 2022 | 10 | 2022 |
| Selective advantage of mutant stem cells in clonal hematopoiesis occurs by attenuating the deleterious effects of inflammation and aging NA Jakobsen, S Turkalj, AGX Zeng, B Stoilova, M Metzner, MS Nagree, ... bioRxiv, 2023.09. 12.557322, 2023 | 9 | 2023 |
| Fundamental trends within falling match rates: insights from the past decade of Canadian residency matching data AGX Zeng, CTA Brenna, S Ndoja Canadian Medical Education Journal 11 (3), e31, 2020 | 8 | 2020 |
| Distinct assemblies of heterodimeric cytokine receptors govern stemness programs in leukemia WL Kan, U Dhagat, KB Kaufmann, TR Hercus, TL Nero, AGX Zeng, ... Cancer Discovery 13 (8), 1922-1947, 2023 | 7 | 2023 |
| Burden of common complex disease variants in the exomes of two healthy centenarian brothers LC Tindale, A Zeng, KL Bretherick, S Leach, N Thiessen, ... Gerontology 62 (1), 58-62, 2015 | 7 | 2015 |
| A hematopoietic stem cell subset that retains memory of prior inflammatory stress accumulates in aging and clonal hematopoiesis AGX Zeng*, MS Nagree*, NA Jakobsen*, S Shah, A Murison, J Cheong, ... bioRxiv, 2023 | 6 | 2023 |