Oxidative stress, protein modification and Alzheimer disease A Tramutola, C Lanzillotta, M Perluigi, DA Butterfield Brain research bulletin 133, 88-96, 2017 | 354 | 2017 |
Intranasal rapamycin ameliorates Alzheimer-like cognitive decline in a mouse model of Down syndrome A Tramutola, C Lanzillotta, E Barone, A Arena, I Zuliani, L Mosca, ... Translational neurodegeneration 7, 1-22, 2018 | 89 | 2018 |
Targeting mitochondria in Alzheimer disease: rationale and perspectives C Lanzillotta, F Di Domenico, M Perluigi, DA Butterfield CNS drugs 33 (10), 957-969, 2019 | 72 | 2019 |
Targeting mTOR to reduce Alzheimer-related cognitive decline: from current hits to future therapies A Tramutola, C Lanzillotta, F Di Domenico Expert Review of Neurotherapeutics 17 (1), 33-45, 2017 | 71 | 2017 |
Brain insulin resistance triggers early onset Alzheimer disease in Down syndrome A Tramutola, C Lanzillotta, F Di Domenico, E Head, DA Butterfield, ... Neurobiology of disease 137, 104772, 2020 | 67 | 2020 |
Loss of biliverdin reductase-A favors Tau hyper-phosphorylation in Alzheimer's disease N Sharma, A Tramutola, C Lanzillotta, A Arena, C Blarzino, T Cassano, ... Neurobiology of Disease 125, 176-189, 2019 | 63 | 2019 |
Restoration of aberrant mTOR signaling by intranasal rapamycin reduces oxidative damage: Focus on HNE-modified proteins in a mouse model of down syndrome F Di Domenico, A Tramutola, E Barone, C Lanzillotta, O Defever, A Arena, ... Redox biology 23, 101162, 2019 | 62 | 2019 |
Activation of p53 in Down syndrome and in the Ts65Dn mouse brain is associated with a pro-apoptotic phenotype A Tramutola, G Pupo, F Di Domenico, E Barone, A Arena, C Lanzillotta, ... Journal of Alzheimer's Disease 52 (1), 359-371, 2016 | 44 | 2016 |
Proteomic identification of altered protein O-GlcNAcylation in a triple transgenic mouse model of Alzheimer's disease A Tramutola, N Sharma, E Barone, C Lanzillotta, A Castellani, F Iavarone, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1864 (10 …, 2018 | 42 | 2018 |
Increased mammalian target of rapamycin signaling contributes to the accumulation of protein oxidative damage in a mouse model of Down's syndrome A Tramutola, C Lanzillotta, A Arena, E Barone, M Perluigi, F Di Domenico Neurodegenerative Diseases 16 (1-2), 62-68, 2016 | 41 | 2016 |
Insulin resistance, oxidative stress and mitochondrial defects in Ts65dn mice brain: A harmful synergistic path in down syndrome C Lanzillotta, A Tramutola, G Di Giacomo, F Marini, DA Butterfield, ... Free Radical Biology and Medicine 165, 152-170, 2021 | 38 | 2021 |
Chronic PERK induction promotes Alzheimer-like neuropathology in Down syndrome: Insights for therapeutic intervention C Lanzillotta, I Zuliani, A Tramutola, E Barone, C Blarzino, V Folgiero, ... Progress in Neurobiology 196, 101892, 2021 | 37 | 2021 |
Reduced biliverdin reductase-A levels are associated with early alterations of insulin signaling in obesity FA Cimini, A Arena, I Barchetta, A Tramutola, V Ceccarelli, C Lanzillotta, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1865 (6 …, 2019 | 37 | 2019 |
Stress responses in down syndrome neurodegeneration: state of the art and therapeutic molecules C Lanzillotta, F Di Domenico Biomolecules 11 (2), 266, 2021 | 31 | 2021 |
High-fat diet leads to reduced protein O-GlcNAcylation and mitochondrial defects promoting the development of Alzheimer’s disease signatures I Zuliani, C Lanzillotta, A Tramutola, E Barone, M Perluigi, S Rinaldo, ... International journal of molecular sciences 22 (7), 3746, 2021 | 26 | 2021 |
Identification of changes in neuronal function as a consequence of aging and tauopathic neurodegeneration using a novel and sensitive magnetic resonance imaging approach SN Fontaine, A Ingram, RA Cloyd, SE Meier, E Miller, D Lyons, GK Nation, ... Neurobiology of aging 56, 78-86, 2017 | 26 | 2017 |
The disturbance of protein synthesis/degradation homeostasis is a common trait of age-related neurodegenerative disorders F Di Domenico, C Lanzillotta Advances in protein chemistry and structural biology 132, 49-87, 2022 | 25 | 2022 |
Protein nitration profile of CD3+ lymphocytes from Alzheimer disease patients: Novel hints on immunosenescence and biomarker detection A Tramutola, G Abate, C Lanzillotta, F Triani, E Barone, F Iavarone, ... Free Radical Biology and Medicine 129, 430-439, 2018 | 24 | 2018 |
Therapeutic potential of rescuing protein O-GlcNAcylation in tau-related pathologies F Di Domenico, C Lanzillotta, A Tramutola Expert review of neurotherapeutics 19 (1), 1-3, 2019 | 23 | 2019 |
Early and selective activation and subsequent alterations to the unfolded protein response in down syndrome mouse models C Lanzillotta, A Tramutola, S Meier, F Schmitt, E Barone, M Perluigi, ... Journal of Alzheimer's Disease 62 (1), 347-359, 2018 | 23 | 2018 |