Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant hemorrhage (CRASH-2): a randomized, placebo-controlled … H Shakur, I Roberts 50 Landmark Papers every Trauma Surgeon Should Know, 31-34, 2019 | 3061 | 2019 |
Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (WOMAN): an international, randomised … H Shakur, I Roberts, B Fawole, R Chaudhri, M El-Sheikh, A Akintan, ... The Lancet 389 (10084), 2105-2116, 2017 | 1590 | 2017 |
Predicting outcome after traumatic brain injury: practical prognostic models based on large cohort of international patients MRC Crash Trial Collaborators Bmj 336 (7641), 425-429, 2008 | 1391 | 2008 |
Effect of intravenous corticosteroids on death within 14 days in 10 008 adults with clinically significant head injury (MRC CRASH trial): randomised placebo-controlled trial CRASH Trial Collaborators The Lancet 364 (9442), 1321-1328, 2004 | 1359 | 2004 |
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis K Ker, P Edwards, P Perel, H Shakur, I Roberts Bmj 344, 2012 | 1128 | 2012 |
Treatment for primary postpartum haemorrhage HA Mousa, J Blum, G Abou El Senoun, H Shakur, Z Alfirevic Cochrane database of systematic reviews, 2014 | 1012 | 2014 |
Final results of MRC CRASH, a randomised placebo-controlled trial of intravenous corticosteroid in adults with head injury—outcomes at 6 months CRASH Trial Collaborators The Lancet 365 (9475), 1957-1959, 2005 | 988 | 2005 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in … I Roberts, H Shakur, T Coats, B Hunt, E Balogun, L Barnetson, L Cook, ... Health Technol Assess 17 (10), 1-79, 2013 | 844 | 2013 |
The WOMAN Trial (World Maternal Antifibrinolytic Trial): tranexamic acid for the treatment of postpartum haemorrhage: an international randomised, double blind placebo … H Shakur, D Elbourne, M Gülmezoglu, Z Alfirevic, C Ronsmans, E Allen, ... Trials 11, 1-14, 2010 | 433 | 2010 |
Effect of treatment delay on the effectiveness and safety of antifibrinolytics in acute severe haemorrhage: a meta-analysis of individual patient-level data from 40 138 … A Gayet-Ageron, D Prieto-Merino, K Ker, H Shakur, FX Ageron, I Roberts, ... The Lancet 391 (10116), 125-132, 2018 | 400 | 2018 |
Antifibrinolytic drugs for acute traumatic injury K Ker, I Roberts, H Shakur, TJ Coats Cochrane Database of Systematic Reviews, 2015 | 381 | 2015 |
Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international … I Roberts, H Shakur-Still, A Afolabi, A Akere, M Arribas, A Brenner, ... The Lancet 395 (10241), 1927-1936, 2020 | 368 | 2020 |
Patient outcome after traumatic brain injury in high-, middle-and low-income countries: analysis of data on 8927 patients in 46 countries MJ De Silva, I Roberts, P Perel, P Edwards, MG Kenward, J Fernandes, ... International journal of epidemiology 38 (2), 452-458, 2009 | 359 | 2009 |
CRASH-2 trial collaborators. Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a … H Shakur, I Roberts, R Bautista, J Caballero, T Coats, Y Dewan, ... Lancet 376 (9734), 23-32, 2010 | 341 | 2010 |
Cost-effectiveness analysis of administering tranexamic acid to bleeding trauma patients using evidence from the CRASH-2 trial C Guerriero, J Cairns, P Perel, H Shakur, I Roberts, ... PloS one 6 (5), e18987, 2011 | 239 | 2011 |
Comparative effectiveness, safety and acceptability of medical abortion at home and in a clinic: a systematic review TD Ngo, MH Park, H Shakur, C Free Bulletin of the World Health Organization 89, 360-370, 2011 | 223 | 2011 |
CRASH-3-tranexamic acid for the treatment of significant traumatic brain injury: study protocol for an international randomized, double-blind, placebo-controlled trial Y Dewan, EO Komolafe, JH Mejía-Mantilla, P Perel, I Roberts, H Shakur Trials 13, 1-14, 2012 | 214 | 2012 |
Anti-fibrinolytic agents in post partum haemorrhage: a systematic review P Ferrer, I Roberts, E Sydenham, K Blackhall, H Shakur BMC pregnancy and childbirth 9, 1-6, 2009 | 196 | 2009 |
COVID-19: Progress in diagnostics, therapy and vaccination X Liu, C Liu, G Liu, W Luo, N Xia Theranostics 10 (17), 7821, 2020 | 180 | 2020 |
Effect of tranexamic acid on mortality in patients with traumatic bleeding: prespecified analysis of data from randomised controlled trial I Roberts, P Perel, D Prieto-Merino, H Shakur, T Coats, BJ Hunt, F Lecky, ... Bmj 345, 2012 | 178 | 2012 |