Secreted factors from brain endothelial cells maintain glioblastoma stem‐like cell expansion through the mTOR pathway EM Galan‐Moya, A Le Guelte, E Lima‐Fernandes, C Thirant, J Dwyer, ... EMBO reports 12 (5), 470-476, 2011 | 152 | 2011 |
CD133, CD15/SSEA-1, CD34 or side populations do not resume tumor-initiating properties of long-term cultured cancer stem cells from human malignant glio-neuronal tumors C Patru, L Romao, P Varlet, L Coulombel, E Raponi, J Cadusseau, ... BMC cancer 10, 1-11, 2010 | 135 | 2010 |
Functional analysis of HOXD9 in human gliomas and glioma cancer stem cells M Tabuse, S Ohta, Y Ohashi, R Fukaya, A Misawa, K Yoshida, T Kawase, ... Molecular cancer 10, 1-14, 2011 | 113 | 2011 |
Differential proteomic analysis of human glioblastoma and neural stem cells reveals HDGF as a novel angiogenic secreted factor C Thirant, EM Galan‐Moya, LG Dubois, S Pinte, P Chafey, C Broussard, ... Stem cells 30 (5), 845-853, 2012 | 108 | 2012 |
ETO2-GLIS2 hijacks transcriptional complexes to drive cellular identity and self-renewal in pediatric acute megakaryoblastic leukemia C Thirant, C Ignacimouttou, CK Lopez, L Le Mouël, C Thiollier, A Siret, ... Cancer cell 31 (3), 452-465, 2017 | 89 | 2017 |
A cell-penetrating peptide based on the interaction between c-Src and connexin43 reverses glioma stem cell phenotype E Gangoso, C Thirant, H Chneiweiss, JM Medina, A Tabernero Cell death & disease 5 (1), e1023-e1023, 2014 | 86 | 2014 |
Clinical relevance of tumor cells with stem-like properties in pediatric brain tumors C Thirant, B Bessette, P Varlet, S Puget, J Cadusseau, ... PloS one 6 (1), e16375, 2011 | 86 | 2011 |
Plasticity in neuroblastoma cell identity defines a noradrenergic-to-mesenchymal transition (NMT) M Gautier, C Thirant, O Delattre, I Janoueix-Lerosey Cancers 13 (12), 2904, 2021 | 60 | 2021 |
Sirtuin-2 activity is required for glioma stem cell proliferation arrest but not necrosis induced by resveratrol S Sayd, C Thirant, EA El-Habr, J Lipecka, LG Dubois, A Bogeas, ... Stem Cell Reviews and Reports 10, 103-113, 2014 | 59 | 2014 |
Ontogenic changes in hematopoietic hierarchy determine pediatric specificity and disease phenotype in fusion oncogene–driven myeloid leukemia CK Lopez, E Noguera, V Stavropoulou, E Robert, Z Aid, P Ballerini, ... Cancer discovery 9 (12), 1736-1753, 2019 | 51 | 2019 |
Regulation of sensory neuron-specific acid-sensing ion channel 3 by the adaptor protein Na+/H+ exchanger regulatory factor-1 E Deval, V Friend, C Thirant, M Salinas, M Jodar, M Lazdunski, ... Journal of Biological Chemistry 281 (3), 1796-1807, 2006 | 47 | 2006 |
Reversible transitions between noradrenergic and mesenchymal tumor identities define cell plasticity in neuroblastoma C Thirant, A Peltier, S Durand, A Kramdi, C Louis-Brennetot, ... Nature communications 14 (1), 2575, 2023 | 46 | 2023 |
Human erythroleukemia genetics and transcriptomes identify master transcription factors as functional disease drivers A Fagnan, FO Bagger, MR Piqué-Borràs, C Ignacimouttou, A Caulier, ... Blood, The Journal of the American Society of Hematology 136 (6), 698-714, 2020 | 45 | 2020 |
Single-cell transcriptomics reveals shared immunosuppressive landscapes of mouse and human neuroblastoma A Costa, C Thirant, A Kramdi, C Pierre-Eugène, C Louis-Brennetot, ... Journal for immunotherapy of cancer 10 (8), e004807, 2022 | 32 | 2022 |
Nuclear interacting SET domain protein 1 inactivation impairs GATA1-regulated erythroid differentiation and causes erythroleukemia K Leonards, M Almosailleakh, S Tauchmann, FO Bagger, C Thirant, ... Nature communications 11 (1), 2807, 2020 | 21 | 2020 |
Proteomic analysis of oligodendrogliomas expressing a mutant isocitrate dehydrogenase‐1 C Thirant, P Varlet, J Lipecka, M Le Gall, C Broussard, P Chafey, ... Proteomics 11 (21), 4139-4154, 2011 | 20 | 2011 |
Alkaloids from Rutaceae: activities of canthin-6-one alkaloids and synthetic analogues on glioblastoma stems cells G Cebrián-Torrejón, SA Kahn, ME Ferreira, C Thirant, AR de Arias, ... MedChemComm 3 (7), 771-774, 2012 | 18 | 2012 |
Chromosomal translocation formation is sufficient to produce fusion circular RNAs specific to patient tumor cells L Babin, M Piganeau, B Renouf, K Lamribet, C Thirant, L Deriano, ... IScience 5, 19-29, 2018 | 16 | 2018 |
Screening of ETO2-GLIS2–induced Super Enhancers identifies targetable cooperative dependencies in acute megakaryoblastic leukemia S Benbarche, CK Lopez, E Salataj, Z Aid, C Thirant, MC Laiguillon, ... Science advances 8 (6), eabg9455, 2022 | 15 | 2022 |
Molecular pathways driven by ETO2-GLIS2 in aggressive pediatric leukemia C Thirant, C Lopez, S Malinge, T Mercher Molecular & cellular oncology 4 (6), e1345351, 2017 | 15 | 2017 |