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Jason Locasale
Jason Locasale
Duke University
Bestätigte E-Mail-Adresse bei alum.mit.edu - Startseite
Titel
Zitiert von
Zitiert von
Jahr
The Warburg effect: how does it benefit cancer cells?
MV Liberti, JW Locasale
Trends in biochemical sciences 41 (3), 211-218, 2016
50882016
Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism
H Ying, AC Kimmelman, CA Lyssiotis, S Hua, GC Chu, ...
Cell 149 (3), 656-670, 2012
21372012
Serine, glycine and one-carbon units: cancer metabolism in full circle
JW Locasale
Nature Reviews Cancer 13 (8), 572-583, 2013
16372013
Phosphoenolpyruvate is a metabolic checkpoint of anti-tumor T cell responses
PC Ho, JD Bihuniak, AN Macintyre, M Staron, X Liu, R Amezquita, ...
Cell 162 (6), 1217-1228, 2015
13712015
Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses
D Anastasiou, G Poulogiannis, JM Asara, MB Boxer, J Jiang, M Shen, ...
Science 334 (6060), 1278-1283, 2011
12732011
Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis
JW Locasale, AR Grassian, T Melman, CA Lyssiotis, KR Mattaini, AJ Bass, ...
Nature genetics 43 (9), 869-874, 2011
12262011
Evidence for an alternative glycolytic pathway in rapidly proliferating cells
MG Vander Heiden, JW Locasale, KD Swanson, H Sharfi, GJ Heffron, ...
Science 329 (5998), 1492-1499, 2010
7492010
Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation
VA Gerriets, RJ Kishton, AG Nichols, AN Macintyre, M Inoue, O Ilkayeva, ...
The Journal of clinical investigation 125 (1), 194-207, 2015
7292015
Glutamine metabolism in cancer: understanding the heterogeneity
AA Cluntun, MJ Lukey, RA Cerione, JW Locasale
Trends in cancer 3 (3), 169-180, 2017
6862017
Influence of threonine metabolism on S-adenosylmethionine and histone methylation
N Shyh-Chang, JW Locasale, CA Lyssiotis, Y Zheng, RY Teo, ...
Science 339 (6116), 222-226, 2013
6862013
A roadmap for interpreting 13C metabolite labeling patterns from cells
JM Buescher, MR Antoniewicz, LG Boros, SC Burgess, H Brunengraber, ...
Current opinion in biotechnology 34, 189-201, 2015
6662015
Histone methylation dynamics and gene regulation occur through the sensing of one-carbon metabolism
SJ Mentch, M Mehrmohamadi, L Huang, X Liu, D Gupta, D Mattocks, ...
Cell metabolism 22 (5), 861-873, 2015
6402015
Distinct regulation of Th17 and Th1 cell differentiation by glutaminase-dependent metabolism
MO Johnson, MM Wolf, MZ Madden, G Andrejeva, A Sugiura, ...
Cell 175 (7), 1780-1795. e19, 2018
6092018
Dietary methionine influences therapy in mouse cancer models and alters human metabolism
X Gao, SM Sanderson, Z Dai, MA Reid, DE Cooper, M Lu, JP Richie Jr, ...
Nature 572 (7769), 397-401, 2019
5532019
Metabolic flux and the regulation of mammalian cell growth
JW Locasale, LC Cantley
Cell metabolism 14 (4), 443-451, 2011
5322011
Foxp3 and Toll-like receptor signaling balance Treg cell anabolic metabolism for suppression
VA Gerriets, RJ Kishton, MO Johnson, S Cohen, PJ Siska, AG Nichols, ...
Nature immunology 17 (12), 1459-1466, 2016
5222016
Metabolomics in cancer research and emerging applications in clinical oncology
DR Schmidt, R Patel, DG Kirsch, CA Lewis, MG Vander Heiden, ...
CA: a cancer journal for clinicians 71 (4), 333-358, 2021
5182021
Metabolomics: a primer
X Liu, JW Locasale
Trends in biochemical sciences 42 (4), 274-284, 2017
4962017
The impact of cellular metabolism on chromatin dynamics and epigenetics
MA Reid, Z Dai, JW Locasale
Nature cell biology 19 (11), 1298-1306, 2017
4772017
T cell stemness and dysfunction in tumors are triggered by a common mechanism
SK Vodnala, R Eil, RJ Kishton, M Sukumar, TN Yamamoto, NH Ha, ...
Science 363 (6434), eaau0135, 2019
4752019
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