| The human side of microglia AM Smith, M Dragunow Trends in neurosciences 37 (3), 125-135, 2014 | 283 | 2014 |
| Reactive astrocytes acquire neuroprotective as well as deleterious signatures in response to Tau and Aß pathology Z Jiwaji, SS Tiwari, RX Avilés-Reyes, M Hooley, D Hampton, M Torvell, ... Nature communications 13 (1), 135, 2022 | 156 | 2022 |
| PU. 1 regulates Alzheimer’s disease-associated genes in primary human microglia J Rustenhoven, AM Smith, LC Smyth, D Jansson, EL Scotter, ... Molecular neurodegeneration 13, 1-16, 2018 | 139 | 2018 |
| The transcription factor PU. 1 is critical for viability and function of human brain microglia AM Smith, HM Gibbons, RL Oldfield, PM Bergin, EW Mee, RLM Faull, ... Glia 61 (6), 929-942, 2013 | 138 | 2013 |
| Diverse human astrocyte and microglial transcriptional responses to Alzheimer’s pathology AM Smith, K Davey, S Tsartsalis, C Khozoie, N Fancy, SS Tang, E Liaptsi, ... Acta Neuropathologica 143 (1), 75-91, 2022 | 130 | 2022 |
| M-CSF increases proliferation and phagocytosis while modulating receptor and transcription factor expression in adult human microglia AM Smith, HM Gibbons, RL Oldfield, PM Bergin, EW Mee, MA Curtis, ... Journal of neuroinflammation 10, 1-15, 2013 | 125 | 2013 |
| Mitochondrial dysfunction and increased glycolysis in prodromal and early Parkinson's blood cells AM Smith, C Depp, BJ Ryan, GI Johnston, J Alegre‐Abarrategui, S Evetts, ... Movement Disorders 33 (10), 1580-1590, 2018 | 108 | 2018 |
| Isolation of highly enriched primary human microglia for functional studies J Rustenhoven, TIH Park, P Schweder, J Scotter, J Correia, AM Smith, ... Scientific reports 6 (1), 19371, 2016 | 102 | 2016 |
| Translocator protein is a marker of activated microglia in rodent models but not human neurodegenerative diseases E Nutma, N Fancy, M Weinert, S Tsartsalis, MC Marzin, RCJ Muirhead, ... Nature communications 14 (1), 5247, 2023 | 97 | 2023 |
| Valproic acid induces microglial dysfunction, not apoptosis, in human glial cultures HM Gibbons, AM Smith, HH Teoh, PM Bergin, EW Mee, RLM Faull, ... Neurobiology of disease 41 (1), 96-103, 2011 | 69 | 2011 |
| Valproic acid enhances microglial phagocytosis of amyloid-β1–42 AM Smith, HM Gibbons, M Dragunow Neuroscience 169 (1), 505-515, 2010 | 66 | 2010 |
| Adult Human Glia, Pericytes and Meningeal Fibroblasts Respond Similarly to IFNy but Not to TGFβ1 or M-CSF AM Smith, ES Graham, SX Feng, RL Oldfield, PM Bergin, EW Mee, ... PloS one 8 (12), e80463, 2013 | 49 | 2013 |
| Cross-platform transcriptional profiling identifies common and distinct molecular pathologies in Lewy body diseases R Feleke, RH Reynolds, AM Smith, B Tilley, SAG Taliun, J Hardy, ... Acta neuropathologica 142, 449-474, 2021 | 48 | 2021 |
| Preclinical development of a vaccine against oligomeric alpha-synuclein based on virus-like particles M Doucet, A El-Turabi, F Zabel, BHM Hunn, N Bengoa-Vergniory, ... PLoS One 12 (8), e0181844, 2017 | 41 | 2017 |
| Routine culture and study of adult human brain cells from neurosurgical specimens TIH Park, LCD Smyth, M Aalderink, ZR Woolf, J Rustenhoven, K Lee, ... Nature Protocols 17 (2), 190-221, 2022 | 26 | 2022 |
| A single nuclear transcriptomic characterisation of mechanisms responsible for impaired angiogenesis and blood-brain barrier function in Alzheimer’s disease S Tsartsalis, H Sleven, N Fancy, F Wessely, AM Smith, N Willumsen, ... Nature Communications 15 (1), 2243, 2024 | 24 | 2024 |
| Isolation and culture of adult human microglia within mixed glial cultures for functional experimentation and high-content analysis AM Smith, HM Gibbons, C Lill, RLM Faull, M Dragunow Microglia: Methods and Protocols, 41-51, 2013 | 19 | 2013 |
| Characterisation of premature cell senescence in Alzheimer’s disease using single nuclear transcriptomics NN Fancy, AM Smith, A Caramello, S Tsartsalis, K Davey, RCJ Muirhead, ... Acta Neuropathologica 147 (1), 1-21, 2024 | 14 | 2024 |
| Single nuclear transcriptional signatures of dysfunctional brain vascular homeostasis in Alzheimer’s disease S Tsartsalis, N Fancy, AM Smith, C Khozoie, X Yang, K Davey, ... Biorxiv, 2021.10. 27.465860, 2021 | 6 | 2021 |
| Distinct characteristics of microglia from neurogenic and non-neurogenic regions of the human brain in patients with Mesial Temporal Lobe Epilepsy AM Smith, TIH Park, M Aalderink, RL Oldfield, PS Bergin, EW Mee, ... Frontiers in Cellular Neuroscience 16, 1047928, 2022 | 4 | 2022 |
