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Alvin WT Ng
Alvin WT Ng
Presidential Postdoctoral Fellow at Lee Kong Chian School of Medicine, Singapore
Bestätigte E-Mail-Adresse bei ntu.edu.sg
Titel
Zitiert von
Zitiert von
Jahr
The repertoire of mutational signatures in human cancer
LB Alexandrov, J Kim, NJ Haradhvala, MN Huang, AWT Ng, Y Wu, A Boot, ...
Nature 578 (7793), 94-101, 2020
30622020
Pan-cancer analysis of whole genomes.
S Hirano, L Yang, M Juul, CA Purdie, BP O'Neill, R Kabbe, ...
Nature 578 (DKFZ-2020-01051), 82-93, 2020
2002*2020
Whole-genome and epigenomic landscapes of etiologically distinct subtypes of cholangiocarcinoma
A Jusakul, I Cutcutache, CH Yong, JQ Lim, MN Huang, N Padmanabhan, ...
Cancer Discovery 7 (10), 1116-1135, 2017
8432017
Aristolochic acids and their derivatives are widely implicated in liver cancers in Taiwan and throughout Asia
AWT Ng, SL Poon, MN Huang, JQ Lim, A Boot, W Yu, Y Suzuki, ...
Science translational medicine 9 (412), eaan6446, 2017
3702017
Global epidemiology and genetics of hepatocellular carcinoma
MR Toh, EYT Wong, SH Wong, AWT Ng, LH Loo, PKH Chow, J Ngeow
Gastroenterology 164 (5), 766-782, 2023
2882023
In-depth characterization of the cisplatin mutational signature in human cell lines and in esophageal and liver tumors
A Boot, MN Huang, AWT Ng, SC Ho, JQ Lim, Y Kawakami, K Chayama, ...
Genome research 28 (5), 654-665, 2018
1592018
Genome-scale mutational signatures of aflatoxin in cells, mice, and human tumors
MN Huang, W Yu, WW Teoh, M Ardin, A Jusakul, AWT Ng, A Boot, ...
Genome research 27 (9), 1475-1486, 2017
1222017
Extrachromosomal DNA in the cancerous transformation of Barrett’s oesophagus
J Luebeck, AWT Ng, PC Galipeau, X Li, CA Sanchez, ...
Nature, 1-8, 2023
872023
Experimental and pan-cancer genome analyses reveal widespread contribution of acrylamide exposure to carcinogenesis in humans
M Zhivagui, AWT Ng, M Ardin, MI Churchwell, M Pandey, C Renard, ...
Genome research 29 (4), 521-531, 2019
872019
Epigenomic Promoter Alterations Amplify Gene Isoform and Immunogenic Diversity in Gastric Adenocarcinoma
A Qamra, M Xing, N Padmanabhan, JJT Kwok, S Zhang, C Xu, YS Leong, ...
Cancer Discovery 7 (6), 630-651, 2017
562017
Characterization of colibactin-associated mutational signature in an Asian oral squamous cell carcinoma and in other mucosal tumor types
A Boot, AWT Ng, FT Chong, SC Ho, W Yu, DSW Tan, NG Iyer, SG Rozen
Genome research 30 (6), 803-813, 2020
512020
The Drosophila Dicer-1 Partner Loquacious Enhances miRNA Processing from Hairpins with Unstable Structures at the Dicing Site
MYT Lim, AWT Ng, Y Chou, TP Lim, A Simcox, G Tucker-Kellogg, ...
Cell reports 15 (8), 1795-1808, 2016
282016
Functional genomics identifies specific vulnerabilities in PTEN-deficient breast cancer
YC Tang, SC Ho, E Tan, AWT Ng, JR McPherson, GYL Goh, BT Teh, ...
Breast Cancer Research 20 (1), 22, 2018
232018
Serial circulating tumor DNA detection using a personalized, tumor-informed assay in esophageal adenocarcinoma patients following resection
E Ococks, S Sharma, AWT Ng, A Aleshin, RC Fitzgerald, E Smyth
Gastroenterology 161 (5), 1705-1708. e2, 2021
172021
Rearrangement processes and structural variations show evidence of selection in oesophageal adenocarcinomas
AWT Ng, G Contino, S Killcoyne, G Devonshire, R Hsu, S Abbas, J Su, ...
Communications Biology 5 (1), 1-12, 2022
142022
TEX264 drives selective autophagy of DNA lesions to promote DNA repair and cell survival
P Lascaux, G Hoslett, S Tribble, C Trugenberger, I Antičević, C Otten, ...
Cell, 2024
112024
Accuracy of mutational signature software on correlated signatures
Y Wu, EHZ Chua, AWT Ng, A Boot, SG Rozen
Scientific reports 12 (1), 1-12, 2022
102022
Understanding the malignant potential of gastric metaplasia of the oesophagus and its relevance to Barrett’s oesophagus surveillance: individual-level data analysis
EL Black, E Ococks, G Devonshire, AWT Ng, M O’Donovan, S Malhotra, ...
Gut, 2023
82023
DNA epigenetic signature predictive of benefit from neoadjuvant chemotherapy in oesophageal adenocarcinoma: results from the MRC OE02 trial
R Sundar, A Ng, H Zouridis, N Padmanabhan, T Sheng, S Zhang, MH Lee, ...
European Journal of Cancer 123, 48-57, 2019
52019
Disentangling oncogenic amplicons in esophageal adenocarcinoma
AWT Ng, DP McClurg, B Wesley, SA Zamani, E Black, A Miremadi, ...
Nature Communications 15 (1), 4074, 2024
42024
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