| Exosomes secreted by cardiosphere-derived cells reduce scarring, attenuate adverse remodelling, and improve function in acute and chronic porcine myocardial infarction R Gallet, J Dawkins, J Valle, E Simsolo, G De Couto, R Middleton, ... European heart journal 38 (3), 201-211, 2016 | 606 | 2016 |
| Exosomal MicroRNA Transfer Into Macrophages Mediates Cellular Postconditioning G de Couto, R Gallet, L Cambier, E Jaghatspanyan, N Makkar, ... Circulation 136 (2), 200-214, 2017 | 316 | 2017 |
| Macrophages mediate cardioprotective cellular postconditioning in acute myocardial infarction G De Couto, W Liu, E Tseliou, B Sun, N Makkar, H Kanazawa, M Arditi, ... The Journal of clinical investigation 125 (8), 3147-3162, 2015 | 265 | 2015 |
| Y RNA fragment in extracellular vesicles confers cardioprotection via modulation of IL‐10 expression and secretion L Cambier, G de Couto, A Ibrahim, AK Echavez, J Valle, W Liu, M Kreke, ... EMBO molecular medicine 9 (3), 337-352, 2017 | 227 | 2017 |
| Magnetic antibody-linked nanomatchmakers for therapeutic cell targeting K Cheng, D Shen, MT Hensley, R Middleton, B Sun, W Liu, G De Couto, ... Nature communications 5 (1), 4880, 2014 | 159 | 2014 |
| Fibroblasts rendered antifibrotic, antiapoptotic, and angiogenic by priming with cardiosphere-derived extracellular membrane vesicles E Tseliou, J Fouad, H Reich, L Slipczuk, G De Couto, M Aminzadeh, ... Journal of the American College of Cardiology 66 (6), 599-611, 2015 | 157 | 2015 |
| Early detection of myocardial dysfunction and heart failure G De Couto, M Ouzounian, PP Liu Nature reviews Cardiology 7 (6), 334-344, 2010 | 132 | 2010 |
| Cardiosphere-derived cells reverse heart failure with preserved ejection fraction in rats by decreasing fibrosis and inflammation R Gallet, G de Couto, E Simsolo, J Valle, B Sun, W Liu, E Tseliou, MR Zile, ... JACC: Basic to Translational Science 1 (1), 14-28, 2016 | 118 | 2016 |
| Gelsolin regulates cardiac remodeling after myocardial infarction through DNase I–mediated apoptosis GH Li, Y Shi, Y Chen, M Sun, S Sader, Y Maekawa, S Arab, F Dawood, ... Circulation research 104 (7), 896-904, 2009 | 115 | 2009 |
| Survival and cardiac remodeling after myocardial infarction are critically dependent on the host innate immune interleukin-1 receptor-associated kinase-4 signaling: a regulator … Y Maekawa, N Mizue, A Chan, Y Shi, Y Liu, S Dawood, M Chen, ... Circulation 120 (14), 1401-1414, 2009 | 106 | 2009 |
| Cellular post-conditioning: allogeneic cardiosphere-derived cells reduce infarct size and attenuate microvascular obstruction when administered after reperfusion in pigs with … H Kanazawa, E Tseliou, K Malliaras, K Yee, JF Dawkins, G De Couto, ... Circulation: Heart Failure, CIRCHEARTFAILURE. 114.001484, 2015 | 105 | 2015 |
| Cathepsin-L ameliorates cardiac hypertrophy through activation of the autophagy–lysosomal dependent protein processing pathways M Sun, M Ouzounian, G de Couto, M Chen, R Yan, M Fukuoka, G Li, ... Journal of the American Heart Association 2 (2), e000191, 2013 | 101 | 2013 |
| Delayed repolarization underlies ventricular arrhythmias in rats with heart failure and preserved ejection fraction JH Cho, R Zhang, PJ Kilfoil, R Gallet, G de Couto, C Bresee, JI Goldhaber, ... Circulation 136 (21), 2037-2050, 2017 | 82 | 2017 |
| Angiogenesis, cardiomyocyte proliferation and anti-fibrotic effects underlie structural preservation post-infarction by intramyocardially-injected cardiospheres E Tseliou, G De Couto, J Terrovitis, B Sun, L Weixin, L Marbán, E Marbán PloS one 9 (2), e88590, 2014 | 75 | 2014 |
| Mechanism of Enhanced MerTK-Dependent Macrophage Efferocytosis by Extracellular Vesicles G de Couto, E Jaghatspanyan, M DeBerge, W Liu, K Luther, Y Wang, ... Arteriosclerosis, thrombosis, and vascular biology 39 (10), 2082-2096, 2019 | 72 | 2019 |
| Cardiospheres reverse adverse remodeling in chronic rat myocardial infarction: roles of soluble endoglin and Tgf-β signaling E Tseliou, H Reich, G de Couto, J Terrovitis, B Sun, W Liu, E Marbán Basic research in cardiology 109, 1-12, 2014 | 68 | 2014 |
| A comprehensive method for identification of suitable reference genes in extracellular vesicles K Gouin, K Peck, T Antes, JL Johnson, C Li, SD Vaturi, R Middleton, ... Journal of extracellular vesicles 6 (1), 1347019, 2017 | 67 | 2017 |
| Macrophages in cardiac repair: Environmental cues and therapeutic strategies G de Couto Experimental & Molecular Medicine 51 (12), 1-10, 2019 | 56 | 2019 |
| Mechanisms of atrial fibrillation in aged rats with heart failure with preserved ejection fraction TRR Mesquita, R Zhang, G de Couto, J Valle, L Sanchez, RG Rogers, ... Heart rhythm 17 (6), 1025-1033, 2020 | 53 | 2020 |
| Durable benefits of cellular postconditioning: long‐term effects of allogeneic cardiosphere‐derived cells infused after reperfusion in pigs with acute myocardial infarction H Kanazawa, E Tseliou, JF Dawkins, G De Couto, R Gallet, K Malliaras, ... Journal of the American Heart Association 5 (2), e002796, 2016 | 43 | 2016 |
