Near-infrared absorbing Ru (ii) complexes act as immunoprotective photodynamic therapy (PDT) agents against aggressive melanoma LM Lifshits, JA Roque III, P Konda, S Monro, HD Cole, D von Dohlen, ... Chemical Science 11 (43), 11740-11762, 2020 | 89 | 2020 |
Breaking the barrier: an osmium photosensitizer with unprecedented hypoxic phototoxicity for real world photodynamic therapy JA Roque, PC Barrett, HD Cole, LM Lifshits, G Shi, S Monro, ... Chemical science 11 (36), 9784-9806, 2020 | 86 | 2020 |
Anticancer Agent with Inexplicable Potency in Extreme Hypoxia: Characterizing a Light-Triggered Ruthenium Ubertoxin HD a. Cole, JA Roque, G Shi, LM Lifshits, E Ramasamy, PC Barrett, ... Journal of the American Chemical Society, 2021 | 68 | 2021 |
Intraligand excited states turn a ruthenium oligothiophene complex into a light-triggered Ubertoxin with anticancer effects in extreme hypoxia JA Roque III, HD Cole, PC Barrett, LM Lifshits, RO Hodges, S Kim, ... Journal of the American Chemical Society 144 (18), 8317-8336, 2022 | 51 | 2022 |
TLD1433 photosensitizer inhibits conjunctival melanoma cells in zebrafish ectopic and orthotopic tumour models Q Chen, V Ramu, Y Aydar, A Groenewoud, XQ Zhou, MJ Jager, H Cole, ... Cancers 12 (3), 587, 2020 | 48 | 2020 |
Os (II) oligothienyl complexes as a hypoxia-active photosensitizer class for photodynamic therapy JA Roque III, PC Barrett, HD Cole, LM Lifshits, E Bradner, G Shi, ... Inorganic chemistry 59 (22), 16341-16360, 2020 | 45 | 2020 |
TLD1433-Mediated photodynamic therapy with an optical surface applicator in the treatment of lung cancer cells in vitro S Chamberlain, HD Cole, J Roque III, D Bellnier, SA McFarland, ... Pharmaceuticals 13 (7), 137, 2020 | 38 | 2020 |
Discovery of immunogenic cell death-inducing ruthenium-based photosensitizers for anticancer photodynamic therapy P Konda, LM Lifshits, JA Roque III, HD Cole, CG Cameron, SA McFarland, ... Oncoimmunology 10 (1), 1863626, 2021 | 33 | 2021 |
Singlet Oxygen Formation vs Photodissociation for Light-Responsive Protic Ruthenium Anticancer Compounds: The Oxygenated Substituent Determines Which Pathway Dominates F Qu, RW Lamb, CG Cameron, S Park, O Oladipupo, JL Gray, Y Xu, ... Inorganic chemistry 60 (4), 2138-2148, 2021 | 27 | 2021 |
Modification of amyloid-beta peptide aggregation via photoactivation of strained Ru (II) polypyridyl complexes JC Bataglioli, LMF Gomes, C Maunoir, JR Smith, HD Cole, J McCain, ... Chemical Science 12 (21), 7510-7520, 2021 | 25 | 2021 |
Fine‐Feature Modifications to Strained Ruthenium Complexes Radically Alter Their Hypoxic Anticancer Activity† HD Cole, JA Roque III, LM Lifshits, R Hodges, PC Barrett, D Havrylyuk, ... Photochemistry and photobiology 98 (1), 73-84, 2022 | 23 | 2022 |
It Takes Three to Tango: The Length of the Oligothiophene Chain Determines the Nature of the Long‐Lived Excited State and the Resulting Photocytotoxicity of a Ruthenium (II … A Chettri, JA Roque III, KRA Schneider, HD Cole, CG Cameron, ... ChemPhotoChem 5 (5), 421-425, 2021 | 20 | 2021 |
Intracellular photophysics of an osmium complex bearing an oligothiophene extended ligand KRA Schneider, A Chettri, HD Cole, K Reglinski, J Brückmann, ... Chemistry–A European Journal 26 (65), 14844-14851, 2020 | 17 | 2020 |
Ru (II) Phenanthroline-Based Oligothienyl Complexes as Phototherapy Agents HD Cole, A Vali, JA Roque III, G Shi, G Kaur, RO Hodges, ... Inorganic Chemistry 62 (51), 21181-21200, 2023 | 15 | 2023 |
String-attached oligothiophene substituents determine the fate of excited states in ruthenium complexes for photodynamic therapy A Chettri, KRA Schneider, HD Cole, JA Roque III, CG Cameron, ... The Journal of Physical Chemistry A 125 (32), 6985-6994, 2021 | 14 | 2021 |
NIR‐Absorbing RuII Complexes Containing α‐Oligothiophenes for Applications in Photodynamic Therapy LM Lifshits, JA Roque III, HD Cole, RP Thummel, CG Cameron, ... ChemBioChem 21 (24), 3594-3607, 2020 | 14 | 2020 |
Using Biological Photophysics to Map the Excited‐State Topology of Molecular Photosensitizers for Photodynamic Therapy A Chettri, T Yang, HD Cole, G Shi, CG Cameron, SA McFarland, ... Angewandte Chemie International Edition 62 (17), e202301452, 2023 | 13 | 2023 |
Chiral resolution and absolute configuration determination of new metal-based photodynamic therapy antitumor agents DW Armstrong, J Yu, HD Cole, SA McFarland, J Nafie Journal of pharmaceutical and biomedical analysis 204, 114233, 2021 | 12 | 2021 |
Interaction with a biomolecule facilitates the formation of the function-determining long-lived triplet state in a ruthenium complex for photodynamic therapy A Chettri, HD Cole, JA Roque III, KRA Schneider, T Yang, CG Cameron, ... The Journal of Physical Chemistry A 126 (8), 1336-1344, 2022 | 11 | 2022 |
Insights into enantioselective separations of ionic metal complexes by sub/supercritical fluid chromatography TT Handlovic, MF Wahab, HD Cole, N Alatrash, E Ramasamy, ... Analytica chimica acta 1228, 340156, 2022 | 9 | 2022 |