The interplay of the extracellular matrix and stromal cells as a drug target in stroma-rich cancers N Kozlova, JE Grossman, MP Iwanicki, T Muranen Trends in pharmacological sciences 41 (3), 183-198, 2020 | 59 | 2020 |
Increased levels of the HER1 adaptor protein Ruk l /CIN85 contribute to breast cancer malignancy A Samoylenko, B Vynnytska-Myronovska, N Byts, N Kozlova, O Basaraba, ... Carcinogenesis 33 (10), 1976-1984, 2012 | 48 | 2012 |
Hypoxia-inducible factor prolyl hydroxylase 2 (PHD2) is a direct regulator of epidermal growth factor receptor (EGFR) signaling in breast cancer N Kozlova, M Wottawa, DM Katschinski, G Kristiansen, T Kietzmann Oncotarget 8 (6), 9885–9898, 2017 | 40 | 2017 |
PAI-1 modulates cell migration in a LRP1-dependent manner via β-catenin and ERK1/2 N Kozlova, JK Jensen, TF Chi, A Samoylenko, T Kietzmann Thrombosis and haemostasis 113 (05), 988-998, 2015 | 34 | 2015 |
USP28 deficiency promotes breast and liver carcinogenesis as well as tumor angiogenesis in a HIF-independent manner K Richter, T Paakkola, D Mennerich, K Kubaichuk, A Konzack, ... Molecular Cancer Research 16 (6), 1000-1012, 2018 | 29 | 2018 |
Urokinase is a negative modulator of Egf‐dependent proliferation and motility in the two breast cancer cell lines MCF‐7 and MDA‐MB‐231 N Kozlova, A Samoylenko, L Drobot, T Kietzmann Molecular carcinogenesis 55 (2), 170-181, 2016 | 20 | 2016 |
The pro-oncogenic adaptor CIN85 acts as an inhibitory binding partner of hypoxia-inducible factor prolyl hydroxylase 2 N Kozlova, D Mennerich, A Samoylenko, EY Dimova, P Koivunen, ... Cancer Research 79 (16), 4042-4056, 2019 | 14 | 2019 |
The adaptor protein Ruk/CIN85 activates plasminogen activator inhibitor-1 (PAI-1) expression via hypoxia-inducible factor-1α A Samoylenko, EY Dimova, N Kozlova, L Drobot, T Kietzmann Thrombosis and haemostasis 103 (05), 901-909, 2010 | 13 | 2010 |
Recombinant lentivirus-mediated silencing of adaptor protein Ruk/CIN85 expression influences biological responses of tumor cells AA Samoylenko, NV Byts, GV Pasichnyk, NV Kozlova, AV Bazalii, ... Biotechnologia Acta 6 (4), 182, 2013 | 12 | 2013 |
Differences in syncytia formation by SARS-CoV-2 variants modify host chromatin accessibility and cellular senescence via TP53 JD Lee, BL Menasche, M Mavrikaki, MM Uyemura, SM Hong, N Kozlova, ... Cell reports 42 (12), 2023 | 7 | 2023 |
Targeting cholesterol biosynthesis with statins synergizes with AKT inhibitors in triple-negative breast cancer AL Hillis, TD Martin, HE Manchester, J Högström, N Zhang, E Lecky, ... Cancer Research 84 (19), 3250-3266, 2024 | 3 | 2024 |
A novel DNA repair protein, N-Myc downstream regulated gene 1 (NDRG1), links stromal tumour microenvironment to chemoresistance N Kozlova, KA Cruz, HM Doh, AA Ruzette, NA Willis, SM Hong, ... bioRxiv, 2025.01. 22.634323, 2025 | | 2025 |
190 (PB178): BH3 mimetics targeting BCL-XL have efficacy in solid tumors with RB1 loss and replication stress A Varkaris, K Wang, N Kozlova, M Nouri, A Stavridi, D Einstein, J DeBono, ... European Journal of Cancer 211, 114710, 2024 | | 2024 |
Abstract PO2-24-06: Cancer-Associated Fibroblasts Promote Tumor Stemness in Aggressive Breast Cancers via NDRG1 E Villodre, JM Hogstrom, X Hu, N Kozlova, D Tripathy, T Muranen, ... Cancer Research 84 (9_Supplement), PO2-24-06-PO2-24-06, 2024 | | 2024 |
Cholesterol biosynthesis inhibition synergizes with AKT inhibitors in triple-negative breast cancer AL Hillis, TD Martin, HE Manchester, JM Hogstrom, N Zhang, E Lecky, ... | | 2024 |
Abstract PR008: Elucidating the mechanistic role of the MRE11-NDRG1 interaction in DNA repair and chemoresistance HM Doh, N Kozlova, T Muranen Cancer Research 84 (1_Supplement), PR008-PR008, 2024 | | 2024 |
USP28 Deficiency Promotes Breast and Liver Carcinogenesis as well as Tumor Angiogenesis in a HIF-independent Manner (vol 16, pg 1000, 2018) K Richter, T Paakkola, D Mennerich, K Kubaichuk, A Konzack, ... MOLECULAR CANCER RESEARCH 16 (11), 1815-1815, 2018 | | 2018 |
Overexpression of the adaptor protein Rukl/CIN85 increases the oncogenic potential of MCF-7 breast adenocarcinoma cells L Drobot, A Samoylenko, B Vynnytska, N Byts, N Kozlova, K Palyvoda, ... FEBS JOURNAL 278, 232-232, 2011 | | 2011 |
1033 Study of adapter protein Ruk/CIN85 subcellular redistribution after stimulation of HeLa cells with activators of PI3K O Basaraba, N Kozlova, A Pasichnyk, I Dikic, L Drobot EJC Supplements 2 (7), 96-97, 2009 | | 2009 |