| Histone deacetylase inhibitors: from bench to clinic M Paris, M Porcelloni, M Binaschi, D Fattori Journal of medicinal chemistry 51 (6), 1505-1529, 2008 | 471 | 2008 |
| Solid phase synthesis of peptide C-terminal thioesters by Fmoc/t-Bu chemistry R Ingenito, E Bianchi, D Fattori, A Pessi Journal of the American Chemical Society 121 (49), 11369-11374, 1999 | 402 | 1999 |
| Optically Pure 7-Oxabicyclo [2.2. 1] Hept-5-en-2-yl Derivatives (Naked Sugars) as New Chirons P Vogel, D Fattori, F Gasparini, C Le Drian Synlett 1990 (4), 173-185, 1990 | 134 | 1990 |
| Molecular recognition: the fragment approach in lead generation D Fattori Drug Discovery Today 9 (5), 229-238, 2004 | 115 | 2004 |
| α-Ketoacids are potent slow binding inhibitors of the hepatitis C virus NS3 protease F Narjes, M Brunetti, S Colarusso, B Gerlach, U Koch, G Biasiol, D Fattori, ... Biochemistry 39 (7), 1849-1861, 2000 | 91 | 2000 |
| Fragment-based approach to drug lead discovery: overview and advances in various techniques D Fattori, A Squarcia, S Bartoli Drugs in R & D 9 (4), 217-227, 2008 | 72 | 2008 |
| Prime site binding inhibitors of a serine protease: NS3/4A of hepatitis C virus P Ingallinella, D Fattori, S Altamura, C Steinkühler, U Koch, D Cicero, ... Biochemistry 41 (17), 5483-5492, 2002 | 67 | 2002 |
| ChemInform Abstract: The Demjanov and Tiffeneau‐Demjanov One‐Carbon Ring Enlargements of 2‐Aminomethyl‐7‐oxabicyclo (2.2. 1) heptane Derivatives. The Stereo‐and Regioselective … D FATTORI, S HENRY, P VOGEL ChemInform 24 (24), no-no, 1993 | 63* | 1993 |
| Role of charged residues in the catalytic mechanism of hepatitis C virus NS3 protease: electrostatic precollision guidance and transition-state stabilization U Koch, G Biasiol, M Brunetti, D Fattori, M Pallaoro, C Steinkühler Biochemistry 40 (3), 631-640, 2001 | 47 | 2001 |
| Bradykinin receptor antagonists–a review of the patent literature 2005–2008 CI Fincham, A Bressan, M Paris, C Rossi, D Fattori Expert opinion on therapeutic patents 19 (7), 919-941, 2009 | 46 | 2009 |
| The electron-releasing homoconjugated carbonyl group. Application to the total syntheses of 3-deoxy-, 4-deoxy-hexose, lividosamine and derivatives D Fattori, E de Guchteneere, P Vogel Tetrahedron letters 30 (52), 7415-7418, 1989 | 39 | 1989 |
| hNK2 receptor antagonists. The use of intramolecular hydrogen bonding to increase solubility and membrane permeability A Ettorre, P D’Andrea, S Mauro, M Porcelloni, C Rossi, M Altamura, ... Bioorganic & medicinal chemistry letters 21 (6), 1807-1809, 2011 | 35 | 2011 |
| Total asymmetric syntheses of d-lividosamine and 2-acetamido-2, 3-dideoxy-d-arabino-hexose derivatives. E de Guchteneere, D Fattori, P Vogel Tetrahedron 48 (48), 10603-10620, 1992 | 30 | 1992 |
| Fragment-based drug design: combining philosophy with technology. S Bartoli, CI Fincham, D Fattori Current opinion in drug discovery & development 10 (4), 422-429, 2007 | 29 | 2007 |
| ChemInform Abstract: Substituent Effects on the Regioselectivity of the Baeyer‐Villiger Oxidation of 7‐Oxabicyclo (2.2. 1) heptan‐2‐ones. G ARVAI, D FATTORI, P VOGEL ChemInform 24 (13), no-no, 1993 | 28* | 1993 |
| The fragment-approach: an update S Bartoli, CI Fincham, D Fattori Drug Discovery Today: Technologies 3 (4), 425-431, 2006 | 26 | 2006 |
| Probing the active site of the hepatitis C virus serine protease by fluorescence resonance energy transfer D Fattori, A Urbani, M Brunetti, R Ingenito, A Pessi, K Prendergast, ... Journal of Biological Chemistry 275 (20), 15106-15113, 2000 | 26 | 2000 |
| A new method for chemoselective conjugation of unprotected peptides to dauno-and doxorubicin P Ingallinella, A Di Marco, M Taliani, D Fattori, A Pessi Bioorganic & medicinal chemistry letters 11 (10), 1343-1346, 2001 | 25 | 2001 |
| A practical approach to the synthesis of hairpin polyamide–peptide conjugates through the use of a safety-catch linker D Fattori, O Kinzel, P Ingallinella, E Bianchi, A Pessi Bioorganic & medicinal chemistry letters 12 (8), 1143-1147, 2002 | 24 | 2002 |
| Alkyl piperidine and piperazine hydroxamic acids as HDAC inhibitors C Rossi, M Porcelloni, P D’Andrea, CI Fincham, A Ettorre, S Mauro, ... Bioorganic & medicinal chemistry letters 21 (8), 2305-2308, 2011 | 23 | 2011 |
Uwe KochLead-Discovery-CenterBestätigte E-Mail-Adresse bei lead-discovery.de
