Incorporation of sensing modalities into de novo designed fluorescence-activating proteins JC Klima, LA Doyle, JD Lee, M Rappleye, LA Gagnon, MY Lee, EP Barros, ... Nature Communications 12 (1), 856, 2021 | 47 | 2021 |
Identification of variable lymphocyte receptors that can target therapeutics to pathologically exposed brain extracellular matrix BJ Umlauf, PA Clark, JM Lajoie, JV Georgieva, S Bremner, BR Herrin, ... Science advances 5 (5), eaau4245, 2019 | 30 | 2019 |
Full-length dystrophin deficiency leads to contractile and calcium transient defects in human engineered heart tissues SB Bremner, CJ Mandrycky, A Leonard, RM Padgett, AR Levinson, ... Journal of Tissue Engineering 13, 20417314221119628, 2022 | 21 | 2022 |
A Change of Heart: Human Cardiac Tissue Engineering as a Platform for Drug Development SB Bremner, KS Gaffney, NJ Sniadecki, DL Mack Current Cardiology Reports 24 (5), 473-486, 2022 | 20 | 2022 |
Engineered heart tissues for contractile, structural, and transcriptional assessment of human pluripotent stem cell-derived cardiomyocytes in a three-dimensional, auxotonic … S Bremner, AJ Goldstein, T Higashi, NJ Sniadecki Cardiac Tissue Engineering: Methods and Protocols, 87-97, 2022 | 12 | 2022 |
A yeast display immunoprecipitation screen for targeted discovery of antibodies against membrane protein complexes JM Lajoie, YK Cho, D Frost, S Bremner, L Li, EV Shusta Protein Engineering, Design and Selection 32 (5), 219-230, 2019 | 5 | 2019 |
Structure-guided engineering of a fast genetically encoded sensor for real-time H2O2 monitoring JD Lee, W Won, K Kimball, Y Wang, F Yeboah, KM Evitts, C Neiswanger, ... bioRxiv, 2024 | 4 | 2024 |
Far-red and sensitive sensor for monitoring real time H2O2 dynamics with subcellular resolution and in multi-parametric imaging applications JD Lee, A Nguyen, ZR Jin, A Moghadasi, CE Gibbs, SJ Wait, KM Evitts, ... bioRxiv, 2024 | 3 | 2024 |
Incomplete-penetrant hypertrophic cardiomyopathy MYH7 G256E mutation causes hypercontractility and elevated mitochondrial respiration S Lee, AS Vander Roest, CA Blair, K Kao, SB Bremner, MC Childers, ... Proceedings of the National Academy of Sciences 121 (19), e2318413121, 2024 | 2 | 2024 |
Multi-scale models reveal hypertrophic cardiomyopathy MYH7 G256E mutation drives hypercontractility and elevated mitochondrial respiration S Lee, ASV Roest, CA Blair, K Kao, SB Bremner, MC Childers, D Pathak, ... bioRxiv, 2023.06. 08.544276, 2023 | 1 | 2023 |
Engineered Heart Tissues for Standard 96-Well Tissue Culture Plates AJ Goldstein, RM Padgett, SB Bremner, T Higashi, AM Obenaus, ... Tissue Morphogenesis: Methods and Protocols, 89-100, 2024 | | 2024 |
Far-red and sensitive sensor for monitoring real time H2O2 dynamics with subcellular resolution and in multi-parametric imaging applications A Berndt, J Lee, A Nguyen, Z Jin, A Moghadasi, C Gibbs, S Wait, K Evitts, ... Research Square, 2024 | | 2024 |
Ultra-fast genetically encoded sensor for precise real-time monitoring of physiological and pathophysiological peroxide dynamics A Berndt, J Lee, W Won, K Kimball, C Neiswanger, S Schattauer, Y Wang, ... Research Square, 2024 | | 2024 |
Human Engineered Heart Tissues as an In Vitro Model of Duchenne Muscular Dystrophy S Bremner University of Washington, 2022 | | 2022 |
SCIDOT-05. DEVELOPING VARIABLE LYMPHOCYTE RECEPTORS THAT TARGET PATHOLOGICALLY EXPOSED NEURAL ECM TO TREAT GLIOBLASTOMA B J Umlauf, P A Clark, J M Lajoie, J V Georgieva, S Bremner, B R Herrin, ... Neuro-Oncology 21 (Supplement_6), vi273-vi273, 2019 | | 2019 |
EXTH-67. IDENTIFICATION AND DEVELOPMENT OF NEURAL ECM-BINDING LAMPREY ANTIBODIES (VARIABLE LYMPHOCYTE RECEPTORS) THAT TARGET GLIOBLASTOMA B Umlauf, P Clark, J Lajoie, J Georgieva, S Bremner, B Herrin, E Shusta, ... Neuro-Oncology 21 (Suppl 6), vi96, 2019 | | 2019 |