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David Walter
David Walter
Functional Genomics Centre at Cancer Research Horizons
Bestätigte E-Mail-Adresse bei cancer.org.uk - Startseite
Titel
Zitiert von
Zitiert von
Jahr
Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing
P Galanos, K Vougas, D Walter, A Polyzos, A Maya-Mendoza, ...
Nature cell biology 18 (7), 777-789, 2016
3182016
The inhibitor-of-apoptosis protein Bir1p protects against apoptosis in S. cerevisiae and is a substrate for the yeast homologue of Omi/HtrA2
D Walter, S Wissing, F Madeo, B Fahrenkrog
Journal of cell science 119 (9), 1843-1851, 2006
1552006
SCFCyclin F-dependent degradation of CDC6 suppresses DNA re-replication
D Walter, S Hoffmann, ES Komseli, J Rappsilber, V Gorgoulis, ...
Nature communications 7 (1), 10530, 2016
1142016
Histone H4K20 methylation mediated chromatin compaction threshold ensures genome integrity by limiting DNA replication licensing
M Shoaib, D Walter, PJ Gillespie, F Izard, B Fahrenkrog, D Lleres, ...
Nature communications 9 (1), 3704, 2018
992018
Damage-induced DNA replication stalling relies on MAPK-activated protein kinase 2 activity
F Köpper, C Bierwirth, M Schön, M Kunze, I Elvers, D Kranz, P Saini, ...
Proceedings of the National Academy of Sciences 110 (42), 16856-16861, 2013
842013
Histone H4 lysine 20 mono-methylation directly facilitates chromatin openness and promotes transcription of housekeeping genes
M Shoaib, Q Chen, X Shi, N Nair, C Prasanna, R Yang, D Walter, ...
Nature communications 12 (1), 4800, 2021
832021
DNA replication and cancer: From dysfunctional replication origin activities to therapeutic opportunities
AS Boyer, D Walter, CS Sørensen
Seminars in cancer biology 37, 16-25, 2016
762016
Cyclin F suppresses B-Myb activity to promote cell cycle checkpoint control
DK Klein, S Hoffmann, JK Ahlskog, K O’Hanlon, M Quaas, BD Larsen, ...
Nature communications 6 (1), 5800, 2015
762015
Negative regulation of apoptosis in yeast
E Owsianowski, D Walter, B Fahrenkrog
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1783 (7), 1303-1310, 2008
622008
Loss of histone H3 methylation at lysine 4 triggers apoptosis in Saccharomyces cerevisiae
D Walter, A Matter, B Fahrenkrog
PLOS Genetics 10 (1), e1004095, 2014
482014
Bre1p-mediated histone H2B ubiquitylation regulates apoptosis in Saccharomyces cerevisiae
D Walter, A Matter, B Fahrenkrog
Journal of cell science 123 (11), 1931-1939, 2010
482010
Nuclear localisation is crucial for the proapoptotic activity of the HtrA-like serine protease Nma111p
KD Belanger, D Walter, TA Henderson, AL Yelton, TG O'Brien, ...
Journal of Cell Science 122 (21), 3931, 2009
262009
Identification of novel paclitaxel sensitivity genes via lentiviral CRISPR/Cas9 screening in haploid human cells
JR Hunt, S Lawo, D Walter, I Nett, J Yarker, BCS Cross, JD Moore
Cancer Research 76 (14_Supplement), 2059-2059, 2016
12016
A benchmark comparison of CRISPRn guide-RNA design algorithms and generation of small single and dual-targeting libraries to boost screening efficiency
S Lukasiak, A Kalinka, N Gupta, A Papadopoulos, K Saeed, U McDermott, ...
bioRxiv, 2024.05. 17.594311, 2024
2024
CRISPR-Cas9: A tool for rapid target discovery and validation
CM Wiggins, D Walter, P Russell, C Sheridan, C Hudson, J Yarker, ...
Cancer Research 78 (13_Supplement), 2912-2912, 2018
2018
Abstract A25: Synthetic lethal CRISPR-Cas9 screen imply an oncogenic role for FBXW7 mutations in colon cancer
JD Moore, C Hudson, P Russell, G Tiwana, D Walter, CM Wiggins, ...
Molecular Cancer Therapeutics 16 (10_Supplement), A25-A25, 2017
2017
Identifying synthetic lethal targets in colon cancer using CRISPR-Cas9 and siRNA screens
P Russell, D Walter, J Yarker, C Wiggins, J Moore
European Journal of Cancer 1 (69), S129, 2016
2016
Loss of histone H3 methylation at lysine 4 triggers apoptosis in S. cerevisiae
B Fahrenkrog, D Walter, A Matter
YEAST 30, 95-95, 2013
2013
Pooled Phenotypic CRISPR Screening enables the identification of synergistic drug combinations for cancer therapy
D Walter, N McCarthy, J Moore
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