Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing P Galanos, K Vougas, D Walter, A Polyzos, A Maya-Mendoza, ... Nature cell biology 18 (7), 777-789, 2016 | 318 | 2016 |
The inhibitor-of-apoptosis protein Bir1p protects against apoptosis in S. cerevisiae and is a substrate for the yeast homologue of Omi/HtrA2 D Walter, S Wissing, F Madeo, B Fahrenkrog Journal of cell science 119 (9), 1843-1851, 2006 | 155 | 2006 |
SCFCyclin F-dependent degradation of CDC6 suppresses DNA re-replication D Walter, S Hoffmann, ES Komseli, J Rappsilber, V Gorgoulis, ... Nature communications 7 (1), 10530, 2016 | 114 | 2016 |
Histone H4K20 methylation mediated chromatin compaction threshold ensures genome integrity by limiting DNA replication licensing M Shoaib, D Walter, PJ Gillespie, F Izard, B Fahrenkrog, D Lleres, ... Nature communications 9 (1), 3704, 2018 | 99 | 2018 |
Damage-induced DNA replication stalling relies on MAPK-activated protein kinase 2 activity F Köpper, C Bierwirth, M Schön, M Kunze, I Elvers, D Kranz, P Saini, ... Proceedings of the National Academy of Sciences 110 (42), 16856-16861, 2013 | 84 | 2013 |
Histone H4 lysine 20 mono-methylation directly facilitates chromatin openness and promotes transcription of housekeeping genes M Shoaib, Q Chen, X Shi, N Nair, C Prasanna, R Yang, D Walter, ... Nature communications 12 (1), 4800, 2021 | 83 | 2021 |
DNA replication and cancer: From dysfunctional replication origin activities to therapeutic opportunities AS Boyer, D Walter, CS Sørensen Seminars in cancer biology 37, 16-25, 2016 | 76 | 2016 |
Cyclin F suppresses B-Myb activity to promote cell cycle checkpoint control DK Klein, S Hoffmann, JK Ahlskog, K O’Hanlon, M Quaas, BD Larsen, ... Nature communications 6 (1), 5800, 2015 | 76 | 2015 |
Negative regulation of apoptosis in yeast E Owsianowski, D Walter, B Fahrenkrog Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1783 (7), 1303-1310, 2008 | 62 | 2008 |
Loss of histone H3 methylation at lysine 4 triggers apoptosis in Saccharomyces cerevisiae D Walter, A Matter, B Fahrenkrog PLOS Genetics 10 (1), e1004095, 2014 | 48 | 2014 |
Bre1p-mediated histone H2B ubiquitylation regulates apoptosis in Saccharomyces cerevisiae D Walter, A Matter, B Fahrenkrog Journal of cell science 123 (11), 1931-1939, 2010 | 48 | 2010 |
Nuclear localisation is crucial for the proapoptotic activity of the HtrA-like serine protease Nma111p KD Belanger, D Walter, TA Henderson, AL Yelton, TG O'Brien, ... Journal of Cell Science 122 (21), 3931, 2009 | 26 | 2009 |
Identification of novel paclitaxel sensitivity genes via lentiviral CRISPR/Cas9 screening in haploid human cells JR Hunt, S Lawo, D Walter, I Nett, J Yarker, BCS Cross, JD Moore Cancer Research 76 (14_Supplement), 2059-2059, 2016 | 1 | 2016 |
A benchmark comparison of CRISPRn guide-RNA design algorithms and generation of small single and dual-targeting libraries to boost screening efficiency S Lukasiak, A Kalinka, N Gupta, A Papadopoulos, K Saeed, U McDermott, ... bioRxiv, 2024.05. 17.594311, 2024 | | 2024 |
CRISPR-Cas9: A tool for rapid target discovery and validation CM Wiggins, D Walter, P Russell, C Sheridan, C Hudson, J Yarker, ... Cancer Research 78 (13_Supplement), 2912-2912, 2018 | | 2018 |
Abstract A25: Synthetic lethal CRISPR-Cas9 screen imply an oncogenic role for FBXW7 mutations in colon cancer JD Moore, C Hudson, P Russell, G Tiwana, D Walter, CM Wiggins, ... Molecular Cancer Therapeutics 16 (10_Supplement), A25-A25, 2017 | | 2017 |
Identifying synthetic lethal targets in colon cancer using CRISPR-Cas9 and siRNA screens P Russell, D Walter, J Yarker, C Wiggins, J Moore European Journal of Cancer 1 (69), S129, 2016 | | 2016 |
Loss of histone H3 methylation at lysine 4 triggers apoptosis in S. cerevisiae B Fahrenkrog, D Walter, A Matter YEAST 30, 95-95, 2013 | | 2013 |
Pooled Phenotypic CRISPR Screening enables the identification of synergistic drug combinations for cancer therapy D Walter, N McCarthy, J Moore | | |