| A multiplexed single-cell CRISPR screening platform enables systematic dissection of the unfolded protein response B Adamson, TM Norman, M Jost, MY Cho, JK Nuñez, Y Chen, JE Villalta, ... Cell 167 (7), 1867-1882. e21, 2016 | 1116 | 2016 |
| Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq JM Replogle, RA Saunders, AN Pogson, JA Hussmann, A Lenail, A Guna, ... Cell 185 (14), 2559-2575. e28, 2022 | 404 | 2022 |
| Molecular recording of mammalian embryogenesis MM Chan, ZD Smith, S Grosswendt, H Kretzmer, TM Norman, B Adamson, ... Nature 570 (7759), 77-82, 2019 | 354 | 2019 |
| Exploring genetic interaction manifolds constructed from rich single-cell phenotypes TM Norman, MA Horlbeck, JM Replogle, AY Ge, A Xu, M Jost, LA Gilbert, ... Science 365 (6455), 786-793, 2019 | 279 | 2019 |
| Combined CRISPRi/a-Based Chemical Genetic Screens Reveal that Rigosertib Is a Microtubule-Destabilizing Agent M Jost, Y Chen, LA Gilbert, MA Horlbeck, L Krenning, G Menchon, A Rai, ... Molecular Cell 68 (1), 210-223. e6, 2017 | 238 | 2017 |
| Structural basis for gene regulation by a B12-dependent photoreceptor M Jost, J Fernández-Zapata, MC Polanco, JM Ortiz-Guerrero, PYT Chen, ... Nature 526 (7574), 536-541, 2015 | 195 | 2015 |
| Titrating gene expression using libraries of systematically attenuated CRISPR guide RNAs M Jost, DA Santos, RA Saunders, MA Horlbeck, JS Hawkins, SM Scaria, ... Nature Biotechnology 38 (3), 355-364, 2020 | 155 | 2020 |
| GIGYF2 and 4ehp inhibit translation initiation of defective messenger RNAs to assist Ribosome-Associated quality control KL Hickey, K Dickson, JZ Cogan, JM Replogle, M Schoof, KN D’Orazio, ... Molecular cell 79 (6), 950-962. e6, 2020 | 142 | 2020 |
| A New Facet of Vitamin B12: Gene Regulation by Cobalamin-Based Photoreceptors S Padmanabhan, M Jost, CL Drennan, M Elías-Arnanz Annual review of biochemistry 86, 485-514, 2017 | 123 | 2017 |
| Structure− Function Analysis of an Enzymatic Prenyl Transfer Reaction Identifies a Reaction Chamber with Modifiable Specificity M Jost, G Zocher, S Tarcz, M Matuschek, X Xie, SM Li, T Stehle Journal of the American Chemical Society 132 (50), 17849-17858, 2010 | 112 | 2010 |
| Microfluidics-free single-cell genomics with templated emulsification IC Clark, KM Fontanez, RH Meltzer, Y Xue, C Hayford, A May-Zhang, ... Nature Biotechnology 41 (11), 1557-1566, 2023 | 109 | 2023 |
| Mismatch-CRISPRi Reveals the Co-varying Expression-Fitness Relationships of Essential Genes in Escherichia coli and Bacillus subtilis JS Hawkins, MR Silvis, BM Koo, JM Peters, H Osadnik, M Jost, ... Cell Systems 11 (5), 523-535. e9, 2020 | 103 | 2020 |
| Structure of the catalytic domain of the class I polyhydroxybutyrate synthase from Cupriavidus necator EC Wittenborn, M Jost, Y Wei, JA Stubbe, CL Drennan Journal of Biological Chemistry 291 (48), 25264-25277, 2016 | 96 | 2016 |
| CRISPR approaches to small molecule target identification M Jost, JS Weissman ACS chemical biology 13 (2), 366-375, 2018 | 88 | 2018 |
| The transcription factor CarH safeguards use of adenosylcobalamin as a light sensor by altering the photolysis products M Jost, JH Simpson, CL Drennan Biochemistry 54 (21), 3231-3234, 2015 | 88 | 2015 |
| High-content imaging-based pooled CRISPR screens in mammalian cells X Yan, N Stuurman, SA Ribeiro, ME Tanenbaum, MA Horlbeck, CR Liem, ... Journal of Cell Biology 220 (2), e202008158, 2021 | 76 | 2021 |
| Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors JM Replogle, JL Bonnar, AN Pogson, CR Liem, NK Maier, Y Ding, ... eLife 11, e81856, 2022 | 69 | 2022 |
| DNA repair enzymes ALKBH2, ALKBH3, and AlkB oxidize 5-methylcytosine to 5-hydroxymethylcytosine, 5-formylcytosine and 5-carboxylcytosine in vitro K Bian, SAP Lenz, Q Tang, F Chen, R Qi, M Jost, CL Drennan, ... Nucleic acids research 47 (11), 5522-5529, 2019 | 66 | 2019 |
| Metal binding properties of Escherichia coli YjiA, a member of the metal homeostasis-associated COG0523 family of GTPases AM Sydor, M Jost, KS Ryan, KE Turo, CD Douglas, CL Drennan, ... Biochemistry 52 (10), 1788, 2013 | 62 | 2013 |
| Structure of adenovirus type 21 knob in complex with CD46 reveals key differences in receptor contacts among species B adenoviruses K Cupelli, S Müller, BD Persson, M Jost, N Arnberg, T Stehle Journal of Virology 84 (7), 3189-3200, 2010 | 62 | 2010 |
Jonathan S. WeissmanUCSF/HHMIBestätigte E-Mail-Adresse bei ucsf.edu
