Bioconda: sustainable and comprehensive software distribution for the life sciences B Grüning, R Dale, A Sjödin, BA Chapman, J Rowe, CH Tomkins-Tinch, ... Nature methods 15 (7), 475-476, 2018 | 1219 | 2018 |
ALS-implicated protein TDP-43 sustains levels of STMN2, a mediator of motor neuron growth and repair JR Klim, LA Williams, F Limone, I Guerra San Juan, BN Davis-Dusenbery, ... Nature neuroscience 22 (2), 167-179, 2019 | 517 | 2019 |
GEMINI: integrative exploration of genetic variation and genome annotations U Paila, BA Chapman, R Kirchner, AR Quinlan PLoS computational biology 9 (7), e1003153, 2013 | 491 | 2013 |
A cell atlas of the adult Drosophila midgut RJ Hung, Y Hu, R Kirchner, Y Liu, C Xu, A Comjean, SG Tattikota, F Li, ... Proceedings of the National Academy of Sciences 117 (3), 1514-1523, 2020 | 241 | 2020 |
A family of non-GPCR chemosensors defines an alternative logic for mammalian olfaction PL Greer, DM Bear, JM Lassance, ML Bloom, T Tsukahara, ... Cell 165 (7), 1734-1748, 2016 | 175 | 2016 |
Subcellular transcriptomes and proteomes of developing axon projections in the cerebral cortex A Poulopoulos, AJ Murphy, A Ozkan, P Davis, J Hatch, R Kirchner, ... Nature 565 (7739), 356-360, 2019 | 165 | 2019 |
High-throughput functional comparison of promoter and enhancer activities TA Nguyen, RD Jones, AR Snavely, AR Pfenning, R Kirchner, M Hemberg, ... Genome research 26 (8), 1023-1033, 2016 | 141 | 2016 |
Hepatocyte stress increases expression of yes‐associated protein and transcriptional coactivator with PDZ‐binding motif in hepatocytes to promote parenchymal inflammation and … M Mooring, BH Fowl, SZC Lum, YE Liu, K Yao, S Softic, R Kirchner, ... Hepatology 71 (5), 1813-1830, 2020 | 134 | 2020 |
Whole‐genome sequencing reveals new Alzheimer's disease–associated rare variants in loci related to synaptic function and neuronal development D Prokopenko, SL Morgan, K Mullin, O Hofmann, B Chapman, R Kirchner, ... Alzheimer's & Dementia 17 (9), 1509-1527, 2021 | 83 | 2021 |
Single-cell transcriptomics of the developing lateral geniculate nucleus reveals insights into circuit assembly and refinement BT Kalish, L Cheadle, S Hrvatin, MA Nagy, S Rivera, M Crow, J Gillis, ... Proceedings of the National Academy of Sciences 115 (5), E1051-E1060, 2018 | 76 | 2018 |
A diencephalic dopamine source provides input to the superior colliculus, where D1 and D2 receptors segregate to distinct functional zones AD Bolton, Y Murata, R Kirchner, SY Kim, A Young, T Dang, Y Yanagawa, ... Cell reports 13 (5), 1003-1015, 2015 | 74 | 2015 |
HIV integration site analysis of cellular models of HIV latency with a probe-enriched next-generation sequencing assay S Sunshine, R Kirchner, SS Amr, L Mansur, R Shakhbatyan, M Kim, ... Journal of virology 90 (9), 4511-4519, 2016 | 71 | 2016 |
Sequencing of captive target transcripts identifies the network of regulated genes and functions of primate-specific miR-522 SM Tan, R Kirchner, J Jin, O Hofmann, L McReynolds, W Hide, ... Cell reports 8 (4), 1225-1239, 2014 | 66 | 2014 |
Basal-A triple-negative breast cancer cells selectively rely on RNA splicing for survival S Chan, P Sridhar, R Kirchner, YJ Lock, Z Herbert, S Buonamici, P Smith, ... Molecular cancer therapeutics 16 (12), 2849-2861, 2017 | 50 | 2017 |
edgeRun: an R package for sensitive, functionally relevant differential expression discovery using an unconditional exact test E Dimont, J Shi, R Kirchner, W Hide Bioinformatics 31 (15), 2589-2590, 2015 | 50 | 2015 |
Transcriptional response to Wnt activation regulates the regenerative capacity of the mammalian cochlea A Samarajeewa, DR Lenz, L Xie, H Chiang, R Kirchner, JF Mulvaney, ... Development 145 (23), dev166579, 2018 | 48 | 2018 |
Herpesviral lytic gene functions render the viral genome susceptible to novel editing by CRISPR/Cas9 HS Oh, WM Neuhausser, P Eggan, M Angelova, R Kirchner, KC Eggan, ... Elife 8, e51662, 2019 | 46 | 2019 |
In Vitro Effects of Lead on Gene Expression in Neural Stem Cells and Associations between Up-regulated Genes and Cognitive Scores in Children PJ Wagner, HR Park, Z Wang, R Kirchner, Y Wei, L Su, K Stanfield, ... Environmental health perspectives 125 (4), 721-729, 2017 | 42 | 2017 |
An RNA-binding protein, Lin28, recognizes and remodels G-quartets in the microRNAs (miRNAs) and mRNAs it regulates E O'Day, MTN Le, S Imai, SM Tan, R Kirchner, H Arthanari, O Hofmann, ... Journal of Biological Chemistry 290 (29), 17909-17922, 2015 | 41 | 2015 |
Aβ-accelerated neurodegeneration caused by Alzheimer’s-associated ACE variant R1279Q is rescued by angiotensin system inhibition in mice LK Cuddy, D Prokopenko, EP Cunningham, R Brimberry, P Song, ... Science translational medicine 12 (563), eaaz2541, 2020 | 39 | 2020 |