Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration OJ Sansom, KR Reed, AJ Hayes, H Ireland, H Brinkmann, IP Newton, ... Genes & development 18 (12), 1385-1390, 2004 | 979 | 2004 |
Dynamics of cadherin/catenin complex formation: novel protein interactions and pathways of complex assembly. L Hinck, IS Näthke, J Papkoff, WJ Nelson The Journal of cell biology 125 (6), 1327-1340, 1994 | 838 | 1994 |
A role for the Adenomatous Polyposis Coli protein in chromosome segregation KB Kaplan, AA Burds, JR Swedlow, SS Bekir, PK Sorger, IS Näthke Nature cell biology 3 (4), 429-432, 2001 | 712 | 2001 |
Cadherins, catenins and APC protein: interplay between cytoskeletal complexes and signaling pathways AIM Barth, IS Näthke, WJ Nelson Current opinion in cell biology 9 (5), 683-690, 1997 | 709 | 1997 |
The adenomatous polyposis coli tumor suppressor protein localizes to plasma membrane sites involved in active cell migration. IS Näthke, CL Adams, P Polakis, JH Sellin, WJ Nelson The Journal of cell biology 134 (1), 165-179, 1996 | 611 | 1996 |
Binding of the adenomatous polyposis coli protein to microtubules increases microtubule stability and is regulated by GSK3β phosphorylation J Zumbrunn, K Kinoshita, AA Hyman, IS Näthke Current Biology 11 (1), 44-49, 2001 | 549 | 2001 |
Cell polarity in development and cancer A Wodarz, I Näthke Nature cell biology 9 (9), 1016-1024, 2007 | 465 | 2007 |
Defining interactions and distributions of cadherin and catenin complexes in polarized epithelial cells. IS Näthke, L Hinck, JR Swedlow, J Papkoff, WJ Nelson The Journal of cell biology 125 (6), 1341-1352, 1994 | 418 | 1994 |
A GSK3-binding peptide from FRAT1 selectively inhibits the GSK3-catalysed phosphorylation of Axin and β-catenin GM Thomas, S Frame, M Goedert, I Nathke, P Polakis, P Cohen FEBS letters 458 (2), 247-251, 1999 | 324 | 1999 |
The adenomatous polyposis coli protein: the Achilles heel of the gut epithelium IS Näthke Annu. Rev. Cell Dev. Biol. 20 (1), 337-366, 2004 | 317 | 2004 |
Spindle orientation bias in gut epithelial stem cell compartments is lost in precancerous tissue AJ Quyn, PL Appleton, FA Carey, RJC Steele, N Barker, H Clevers, ... Cell stem cell 6 (2), 175-181, 2010 | 295 | 2010 |
Loss of APC induces polyploidy as a result of a combination of defects in mitosis and apoptosis D Dikovskaya, D Schiffmann, IP Newton, A Oakley, K Kroboth, O Sansom, ... The Journal of cell biology 176 (2), 183-195, 2007 | 223 | 2007 |
Folding and trimerization of clathrin subunits at the triskelion hub IS Näthke, J Heuser, A Lupas, J Stock, CW Turck, FM Brodsky Cell 68 (5), 899-910, 1992 | 188 | 1992 |
The adenomatous polyposis coli protein unambiguously localizes to microtubule plus ends and is involved in establishing parallel arrays of microtubule bundles in highly … MM Mogensen, JB Tucker, JB Mackie, AR Prescott, IS Näthke The Journal of cell biology 157 (6), 1041-1048, 2002 | 182 | 2002 |
DVC1 (C1orf124) recruits the p97 protein segregase to sites of DNA damage EJ Davis, C Lachaud, P Appleton, TJ Macartney, I Näthke, J Rouse Nature structural & molecular biology 19 (11), 1093-1100, 2012 | 180 | 2012 |
β-catenin: a common target for the regulation of cell adhesion by Wnt-1 and Src signaling pathways L Hinck, IS Näthke, J Papkoff, WJ Nelson Trends in biochemical sciences 19 (12), 538-542, 1994 | 170 | 1994 |
Cell regulation by the Apc protein: Apc as master regulator of epithelia BM McCartney, IS Näthke Current opinion in cell biology 20 (2), 186-193, 2008 | 166 | 2008 |
Cytoskeleton out of the cupboard: colon cancer and cytoskeletal changes induced by loss of APC I Näthke Nature Reviews Cancer 6 (12), 967-974, 2006 | 157 | 2006 |
Lack of adenomatous polyposis coli protein correlates with a decrease in cell migration and overall changes in microtubule stability K Kroboth, IP Newton, K Kita, D Dikovskaya, J Zumbrunn, ... Molecular biology of the cell 18 (3), 910-918, 2007 | 155 | 2007 |
Adenomatous polyposis coli on microtubule plus ends in cell extensions can promote microtubule net growth with or without EB1 K Kita, T Wittmann, IS Näthke, CM Waterman-Storer Molecular biology of the cell 17 (5), 2331-2345, 2006 | 152 | 2006 |