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Laurent Mouchiroud
Laurent Mouchiroud
PhD in Biological Sciences
Bestätigte E-Mail-Adresse bei epfl.ch
Titel
Zitiert von
Zitiert von
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The NAD+/sirtuin pathway modulates longevity through activation of mitochondrial UPR and FOXO signaling
L Mouchiroud, RH Houtkooper, N Moullan, E Katsyuba, D Ryu, C Cantó, ...
Cell 154 (2), 430-441, 2013
12802013
Mitonuclear protein imbalance as a conserved longevity mechanism
RH Houtkooper, L Mouchiroud, D Ryu, N Moullan, E Katsyuba, G Knott, ...
Nature 497 (7450), 451-457, 2013
10882013
Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents
D Ryu, L Mouchiroud, PA Andreux, E Katsyuba, N Moullan, ...
Nature medicine 22 (8), 879-888, 2016
8922016
Enhancing mitochondrial proteostasis reduces amyloid-β proteotoxicity
V Sorrentino, M Romani, L Mouchiroud, JS Beck, H Zhang, D D’Amico, ...
Nature 552 (7684), 187-193, 2017
6112017
Tetracyclines disturb mitochondrial function across eukaryotic models: a call for caution in biomedical research
N Moullan, L Mouchiroud, X Wang, D Ryu, EG Williams, A Mottis, ...
Cell reports 10 (10), 1681-1691, 2015
5392015
The mitochondrial unfolded protein response, a conserved stress response pathway with implications in health and disease
V Jovaisaite, L Mouchiroud, J Auwerx
Journal of Experimental Biology 217 (1), 137-143, 2014
3822014
Two conserved histone demethylases regulate mitochondrial stress-induced longevity
C Merkwirth, V Jovaisaite, J Durieux, O Matilainen, SD Jordan, PM Quiros, ...
Cell 165 (5), 1209-1223, 2016
3542016
Emerging roles of the corepressors NCoR1 and SMRT in homeostasis
A Mottis, L Mouchiroud, J Auwerx
Genes & development 27 (8), 819-835, 2013
3272013
NCoR1 is a conserved physiological modulator of muscle mass and oxidative function
H Yamamoto, EG Williams, L Mouchiroud, C Cantó, W Fan, M Downes, ...
Cell 147 (4), 827-839, 2011
3032011
NAD+ repletion improves muscle function in muscular dystrophy and counters global PARylation
D Ryu, H Zhang, ER Ropelle, V Sorrentino, DAG Mázala, L Mouchiroud, ...
Science translational medicine 8 (361), 361ra139-361ra139, 2016
2992016
Pharmacological Inhibition of poly (ADP-ribose) polymerases improves fitness and mitochondrial function in skeletal muscle
E Pirinen, C Canto, YS Jo, L Morato, H Zhang, KJ Menzies, EG Williams, ...
Cell metabolism 19 (6), 1034-1041, 2014
2952014
NAD+ metabolism: A therapeutic target for age-related metabolic disease
L Mouchiroud, RH Houtkooper, J Auwerx
Critical reviews in biochemistry and molecular biology 48 (4), 397-408, 2013
2222013
A screening-based platform for the assessment of cellular respiration in Caenorhabditis elegans
M Koopman, H Michels, BM Dancy, R Kamble, L Mouchiroud, J Auwerx, ...
Nature protocols 11 (10), 1798-1816, 2016
1972016
Tetracycline antibiotics impair mitochondrial function and its experimental use confounds research
IA Chatzispyrou, NM Held, L Mouchiroud, J Auwerx, RH Houtkooper
Cancer research 75 (21), 4446-4449, 2015
1462015
Transcriptional coregulators: fine-tuning metabolism
L Mouchiroud, LJ Eichner, RJ Shaw, J Auwerx
Cell metabolism 20 (1), 26-40, 2014
1272014
Life span extension by resveratrol, rapamycin, and metformin: The promise of dietary restriction mimetics for an healthy aging
L Mouchiroud, L Molin, N Dallière, F Solari
Biofactors 36 (5), 377-382, 2010
1022010
Pyruvate imbalance mediates metabolic reprogramming and mimics lifespan extension by dietary restriction in Caenorhabditis elegans
L Mouchiroud, L Molin, P Kasturi, MN Triba, ME Dumas, MC Wilson, ...
Aging cell 10 (1), 39-54, 2011
932011
An automated microfluidic platform for C. elegans embryo arraying, phenotyping, and long-term live imaging
M Cornaglia, L Mouchiroud, A Marette, S Narasimhan, T Lehnert, ...
Scientific reports 5 (1), 10192, 2015
782015
Lo Sasso G, Huzard D, Aebischer P, Sandi C, Rinsch C, Auwerx J. Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents
D Ryu, L Mouchiroud, PA Andreux, E Katsyuba, N Moullan, ...
Nat Med 22 (8), 879-88, 2016
762016
A homozygous missense mutation in ERAL1, encoding a mitochondrial rRNA chaperone, causes Perrault syndrome
IA Chatzispyrou, M Alders, S Guerrero-Castillo, R Zapata Perez, ...
Human molecular genetics 26 (13), 2541-2550, 2017
742017
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