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Xavier Deupi
Xavier Deupi
Senior Scientist, Paul Scherrer Institute
Bestätigte E-Mail-Adresse bei psi.ch - Startseite
Titel
Zitiert von
Zitiert von
Jahr
Molecular signatures of G-protein-coupled receptors
AJ Venkatakrishnan, X Deupi, G Lebon, CG Tate, GF Schertler, MM Babu
Nature 494 (7436), 185-194, 2013
18222013
Conformational complexity of G-protein-coupled receptors
BK Kobilka, X Deupi
Trends in pharmacological sciences 28 (8), 397-406, 2007
9282007
Coupling ligand structure to specific conformational switches in the β2-adrenoceptor
X Yao, C Parnot, X Deupi, VRP Ratnala, G Swaminath, D Farrens, ...
Nature chemical biology 2 (8), 417-422, 2006
4372006
Diverse activation pathways in class A GPCRs converge near the G-protein-coupling region
AJ Venkatakrishnan, X Deupi, G Lebon, FM Heydenreich, T Flock, ...
Nature 536 (7617), 484-487, 2016
3492016
Energy landscapes as a tool to integrate GPCR structure, dynamics, and function
X Deupi, BK Kobilka
Physiology 25 (5), 293-303, 2010
3382010
Probing the β2 adrenoceptor binding site with catechol reveals differences in binding and activation by agonists and partial agonists
G Swaminath, X Deupi, TW Lee, W Zhu, FS Thian, TS Kobilka, B Kobilka
Journal of Biological Chemistry 280 (23), 22165-22171, 2005
3352005
The effect of ligand efficacy on the formation and stability of a GPCR-G protein complex
XJ Yao, G Vélez Ruiz, MR Whorton, SGF Rasmussen, BT DeVree, ...
Proceedings of the National Academy of Sciences 106 (23), 9501-9506, 2009
3022009
Stabilized G protein binding site in the structure of constitutively active metarhodopsin-II
X Deupi, P Edwards, A Singhal, B Nickle, D Oprian, G Schertler, ...
Proceedings of the National Academy of Sciences 109 (1), 119-124, 2012
2922012
Structural insights into agonist-induced activation of G-protein-coupled receptors
X Deupi, J Standfuss
Current opinion in structural biology 21 (4), 541-551, 2011
2842011
Tracking G-protein-coupled receptor activation using genetically encoded infrared probes
S Ye, E Zaitseva, G Caltabiano, GFX Schertler, TP Sakmar, X Deupi, ...
Nature 464 (7293), 1386-1389, 2010
2782010
Structural insights into biased G protein-coupled receptor signaling revealed by fluorescence spectroscopy
R Rahmeh, M Damian, M Cottet, H Orcel, C Mendre, T Durroux, ...
Proceedings of the National Academy of Sciences 109 (17), 6733-6738, 2012
2362012
Ligand-regulated oligomerization of β2-adrenoceptors in a model lipid bilayer
JJ Fung, X Deupi, L Pardo, XJ Yao, GA Velez-Ruiz, BT DeVree, ...
The EMBO journal 28 (21), 3315-3328, 2009
2262009
Serine and Threonine Residues Bend α-Helices in the chi1 = g- Conformation
JA Ballesteros, X Deupi, M Olivella, EEJ Haaksma, L Pardo
Biophysical journal 79 (5), 2754-2760, 2000
2092000
Backbone NMR reveals allosteric signal transduction networks in the β1-adrenergic receptor
S Isogai, X Deupi, C Opitz, FM Heydenreich, CJ Tsai, F Brueckner, ...
Nature 530 (7589), 237-241, 2016
2042016
The TXP Motif in the Second Transmembrane Helix of CCR5 A STRUCTURAL DETERMINANT OF CHEMOKINE-INDUCED ACTIVATION
C Govaerts, C Blanpain, X Deupi, S Ballet, JA Ballesteros, SJ Wodak, ...
Journal of Biological Chemistry 276 (16), 13217-13225, 2001
1692001
Femtosecond-to-millisecond structural changes in a light-driven sodium pump
P Skopintsev, D Ehrenberg, T Weinert, D James, RK Kar, PJM Johnson, ...
Nature 583 (7815), 314-318, 2020
1602020
The Role of Internal Water Molecules in the Structure and Function of the Rhodopsin Family of G Protein‐Coupled Receptors
L Pardo, X Deupi, N Dölker, ML López‐Rodríguez, M Campillo
ChemBioChem 8 (1), 19-24, 2007
1462007
Activation of G protein-coupled receptors
X Deupi, B Kobilka
Advances in protein chemistry 74, 137-166, 2007
1442007
GPCRmd uncovers the dynamics of the 3D-GPCRome
I Rodríguez-Espigares, M Torrens-Fontanals, JKS Tiemann, ...
Nature Methods 17 (8), 777-787, 2020
1422020
An online resource for GPCR structure determination and analysis
C Munk, E Mutt, V Isberg, LF Nikolajsen, JM Bibbe, T Flock, MA Hanson, ...
Nature methods 16 (2), 151-162, 2019
1412019
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