| Where is the hope for drug discovery? Let history tell the future DX Kong, XJ Li, HY Zhang Drug discovery today 14 (3-4), 115-119, 2009 | 191 | 2009 |
| Marine natural products as sources of novel scaffolds: Achievement and concern DX Kong, YY Jiang, HY Zhang Drug discovery today 21 (15), 884-886, 2010 | 174 | 2010 |
| Distribution patterns of small-molecule ligands in the protein universe and implications for origin of life and drug discovery HF Ji, DX Kong, L Shen, LL Chen, BG Ma, HY Zhang Genome biology 8 (8), R176, 2007 | 79 | 2007 |
| Multiple pharmacological effects of olive oil phenols DP Yang, DX Kong, HY Zhang Food Chemistry 104 (3), 1269-1271, 2007 | 69 | 2007 |
| Cheminformatic insight into the differences between terrestrial and marine originated natural products J Shang, B Hu, J Wang, F Zhu, Y Kang, D Li, H Sun, DX Kong, T Hou Journal of chemical information and modeling 58 (6), 1182-1193, 2018 | 67 | 2018 |
| How many traditional Chinese medicine components have been recognized by modern Western medicine? A chemoinformatic analysis and implications for finding multicomponent drugs DX Kong, XJ Li, GY Tang, HY Zhang ChemMedChem: Chemistry Enabling Drug Discovery 3 (2), 233-236, 2008 | 60 | 2008 |
| Exploring the biologically relevant chemical space for drug discovery ZL Deng, CX Du, X Li, B Hu, ZK Kuang, R Wang, SY Feng, HY Zhang, ... Journal of chemical information and modeling 53 (11), 2820-2828, 2013 | 47 | 2013 |
| Structure-based analysis of the ligand-binding mechanism for DhelOBP21, a C-minus odorant binding protein, from Dastarcus helophoroides (Fairmaire; Coleoptera: Bothrideridae) DZ Li, GQ Yu, SC Yi, Y Zhang, DX Kong, MQ Wang International journal of biological sciences 11 (11), 1281, 2015 | 43 | 2015 |
| Broad-specific antibodies for a generic immunoassay of quinolone: development of a molecular model for selection of haptens based on molecular field-overlapping L Cao, D Kong, J Sui, T Jiang, Z Li, L Ma, H Lin Analytical chemistry 81 (9), 3246-3251, 2009 | 41 | 2009 |
| The impact of oxygen on metabolic evolution: a chemoinformatic investigation YY Jiang, DX Kong, T Qin, X Li, G Caetano-Anolles, HY Zhang PLoS computational biology 8 (3), e1002426, 2012 | 38 | 2012 |
| Historical variation of structural novelty in a natural product library DX Kong, MY Guo, ZH Xiao, LL Chen, HY Zhang Chemistry & biodiversity 8 (11), 1968-1977, 2011 | 37 | 2011 |
| Do biologically relevant compounds have more chance to be drugs? DX Kong, W Ren, W Lü, HY Zhang Journal of chemical information and modeling 49 (10), 2376-2381, 2009 | 34 | 2009 |
| Comparative analyses of structural features and scaffold diversity for purchasable compound libraries J Shang, H Sun, H Liu, F Chen, S Tian, P Pan, D Li, D Kong, T Hou Journal of cheminformatics 9 (1), 25, 2017 | 32 | 2017 |
| How does oxygen rise drive evolution? Clues from oxygen-dependent biosynthesis of nuclear receptor ligands YY Jiang, DX Kong, T Qin, HY Zhang Biochemical and biophysical research communications 391 (2), 1158-1160, 2010 | 31 | 2010 |
| Three-Dimensional Biologically Relevant Spectrum (BRS-3D): Shape Similarity Profile Based on PDB Ligands as Molecular Descriptors B Hu, ZK Kuang, SY Feng, D Wang, SB He, DX Kong Molecules 21 (11), 1554, 2016 | 27 | 2016 |
| Structural Transformation Detection Contributes to Screening of Behaviorally Active Compounds: Dynamic Binding Process Analysis of DhelOBP21 from Dastarcus helophoroides RN Yang, DZ Li, G Yu, SC Yi, Y Zhang, DX Kong, MQ Wang Journal of chemical ecology 43 (11-12), 1033-1045, 2017 | 26 | 2017 |
| Chemoinformatics approaches for traditional Chinese medicine research and case application in anticancer drug discovery XJ Li, DX Kong, HY Zhang Current drug discovery technologies 7 (1), 22-31, 2010 | 24 | 2010 |
| Construction of a genome-scale metabolic network of the plant pathogen Pectobacterium carotovorum provides new strategies for bactericide discovery C Wang, ZL Deng, ZM Xie, XY Chu, JW Chang, DX Kong, BJ Li, ... FEBS letters 589 (3), 285-294, 2015 | 22 | 2015 |
| Drug repurposing based on drug–drug interaction B Zhou, R Wang, P Wu, DX Kong Chemical biology & drug design 85 (2), 137-144, 2015 | 21 | 2015 |
| Quebrachitol: global status and basic research D Wang, S Zhang, Z Chang, DX Kong, Z Zuo Natural products and bioprospecting 7 (1), 113-122, 2017 | 19 | 2017 |