| Distinct roles of GCN5/PCAF‐mediated H3K9ac and CBP/p300‐mediated H3K18/27ac in nuclear receptor transactivation Q Jin, LR Yu, L Wang, Z Zhang, LH Kasper, JE Lee, C Wang, PK Brindle, ... The EMBO journal 30 (2), 249-262, 2011 | 913 | 2011 |
| H3K4 mono-and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation JE Lee, C Wang, S Xu, YW Cho, L Wang, X Feng, A Baldridge, V Sartorelli, ... elife 2, e01503, 2013 | 523 | 2013 |
| H2A. Z Facilitates Access of Active and Repressive Complexes to Chromatin in Embryonic Stem Cell Self-Renewal and Differentiation G Hu, K Cui, D Northrup, C Liu, C Wang, Q Tang, K Ge, D Levens, ... Cell Stem Cell, 2012 | 355 | 2012 |
| CRISPR/Cas9 targeting events cause complex deletions and insertions at 17 sites in the mouse genome HY Shin, C Wang, HK Lee, KH Yoo, X Zeng, T Kuhns, CM Yang, T Mohr, ... Nature communications 8 (1), 15464, 2017 | 328 | 2017 |
| Hierarchy within the mammary STAT5-driven Wap super-enhancer HY Shin, M Willi, KH Yoo, X Zeng, C Wang, G Metser, L Hennighausen Nature genetics 48 (8), 904-911, 2016 | 282 | 2016 |
| Identification of H3K4me1-associated proteins at mammalian enhancers A Local, H Huang, CP Albuquerque, N Singh, AY Lee, W Wang, C Wang, ... Nature genetics 50 (1), 73-82, 2018 | 262 | 2018 |
| Enhancer priming by H3K4 methyltransferase MLL4 controls cell fate transition C Wang, JE Lee, B Lai, TS Macfarlan, S Xu, L Zhuang, C Liu, W Peng, ... Proceedings of the National Academy of Sciences 113 (42), 11871-11876, 2016 | 248 | 2016 |
| UTX regulates mesoderm differentiation of embryonic stem cells independent of H3K27 demethylase activity C Wang, JE Lee, YW Cho, Y Xiao, Q Jin, C Liu, K Ge Proceedings of the National Academy of Sciences 109 (38), 15324-15329, 2012 | 241 | 2012 |
| Histone H3 lysine 4 monomethylation modulates long-range chromatin interactions at enhancers J Yan, SAA Chen, A Local, T Liu, Y Qiu, KM Dorighi, S Preissl, CM Rivera, ... Cell research 28 (2), 204-220, 2018 | 191 | 2018 |
| UTX inhibition as selective epigenetic therapy against TAL1-driven T-cell acute lymphoblastic leukemia A Benyoucef, CG Palii, C Wang, CJ Porter, A Chu, F Dai, V Tremblay, ... Genes & development 30 (5), 508-521, 2016 | 132 | 2016 |
| An epigenetic switch induced by Shh signalling regulates gene activation during development and medulloblastoma growth X Shi, Z Zhang, X Zhan, M Cao, T Satoh, S Akira, K Shpargel, ... Nature communications 5 (1), 1-12, 2014 | 100 | 2014 |
| UTX demethylase activity is required for satellite cell–mediated muscle regeneration H Faralli, C Wang, K Nakka, A Benyoucef, S Sebastian, L Zhuang, A Chu, ... The Journal of clinical investigation 126 (4), 1555-1565, 2016 | 92 | 2016 |
| The histone chaperone Spt6 coordinates histone H3K27 demethylation and myogenesis AH Wang, H Zare, K Mousavi, C Wang, CE Moravec, HI Sirotkin, K Ge, ... The EMBO journal 32 (8), 1075-1086, 2013 | 91 | 2013 |
| MLL4 prepares the enhancer landscape for Foxp3 induction via chromatin looping K Placek, G Hu, K Cui, D Zhang, Y Ding, JE Lee, Y Jang, C Wang, ... Nature immunology 18 (9), 1035-1045, 2017 | 89 | 2017 |
| Hepatic cytochrome P450s metabolize aristolochic acid and reduce its kidney toxicity Y Xiao, M Ge, X Xue, C Wang, H Wang, X Wu, L Li, L Liu, X Qi, Y Zhang, ... Kidney international 73 (11), 1231-1239, 2008 | 88 | 2008 |
| UTX-guided neural crest function underlies craniofacial features of Kabuki syndrome KB Shpargel, J Starmer, C Wang, K Ge, T Magnuson Proceedings of the National Academy of Sciences 114 (43), E9046-E9055, 2017 | 85 | 2017 |
| Fasting-induced JMJD3 histone demethylase epigenetically activates mitochondrial fatty acid β-oxidation S Seok, YC Kim, S Byun, S Choi, Z Xiao, N Iwamori, Y Zhang, C Wang, ... The Journal of clinical investigation 128 (7), 3144-3159, 2018 | 79 | 2018 |
| Gcn5 and PCAF Regulate PPARγ and Prdm16 Expression To Facilitate Brown Adipogenesis Q Jin, C Wang, X Kuang, X Feng, V Sartorelli, H Ying, K Ge, SYR Dent Molecular and cellular biology 34 (19), 3746-3753, 2014 | 73 | 2014 |
| H3. 3K4M destabilizes enhancer H3K4 methyltransferases MLL3/MLL4 and impairs adipose tissue development Y Jang, A Broun, C Wang, YK Park, L Zhuang, JE Lee, E Froimchuk, C Liu, ... Nucleic Acids Research 47 (2), 607-620, 2019 | 68 | 2019 |
| Neural Hedgehog signaling maintains stem cell renewal in the sensory touch dome epithelium Y Xiao, DT Thoresen, JS Williams, C Wang, J Perna, R Petrova, I Brownell Proceedings of the National Academy of Sciences 112 (23), 7195-7200, 2015 | 67 | 2015 |
Kai Ge, PhDSenior Investigator and Acting Branch Chief, NIDDK, NIHBestätigte E-Mail-Adresse bei nih.gov
