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Jeremy M. Simon
Jeremy M. Simon
Dana-Farber Cancer Institute, Harvard T.H. Chan School of Public Health
Bestätigte E-Mail-Adresse bei ds.dfci.harvard.edu
Titel
Zitiert von
Zitiert von
Jahr
An integrated encyclopedia of DNA elements in the human genome
ENCODE Project Consortium
Nature 489 (7414), 57-74, 2012
174972012
The accessible chromatin landscape of the human genome
RE Thurman, E Rynes, R Humbert, J Vierstra, MT Maurano, E Haugen, ...
Nature 489 (7414), 75-82, 2012
32012012
A map of open chromatin in human pancreatic islets
KJ Gaulton, T Nammo, L Pasquali, JM Simon, PG Giresi, MP Fogarty, ...
Nature genetics 42 (3), 255-259, 2010
6582010
Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity
L Song, Z Zhang, LL Grasfeder, AP Boyle, PG Giresi, BK Lee, ...
Genome research 21 (10), 1757-1767, 2011
6452011
Using formaldehyde-assisted isolation of regulatory elements (FAIRE) to isolate active regulatory DNA
JM Simon, PG Giresi, IJ Davis, JD Lieb
Nature protocols 7 (2), 256-267, 2012
4252012
Single-cell transcriptomic analysis of mouse neocortical development
L Loo, JM Simon, L Xing, ES McCoy, JK Niehaus, J Guo, ES Anton, ...
Nature communications 10 (1), 134, 2019
2872019
An oncogenic Ezh2 mutation induces tumors through global redistribution of histone 3 lysine 27 trimethylation
GP Souroullas, WR Jeck, JS Parker, JM Simon, JY Liu, J Paulk, J Xiong, ...
Nature medicine 22 (6), 632-640, 2016
2282016
Variation in chromatin accessibility in human kidney cancer links H3K36 methyltransferase loss with widespread RNA processing defects
JM Simon, KE Hacker, D Singh, AR Brannon, JS Parker, M Weiser, TH Ho, ...
Genome research 24 (2), 241-250, 2014
2152014
VHL substrate transcription factor ZHX2 as an oncogenic driver in clear cell renal cell carcinoma
J Zhang, T Wu, J Simon, M Takada, R Saito, C Fan, XD Liu, E Jonasch, ...
Science 361 (6399), 290-295, 2018
1622018
BRG1/SMARCA4 inactivation promotes non–small cell lung cancer aggressiveness by altering chromatin organization
T Orvis, A Hepperla, V Walter, S Song, J Simon, J Parker, MD Wilkerson, ...
Cancer research 74 (22), 6486-6498, 2014
1472014
Cas9 gene therapy for Angelman syndrome traps Ube3a-ATS long non-coding RNA
JM Wolter, H Mao, G Fragola, JM Simon, JL Krantz, HO Bazick, B Oztemiz, ...
Nature 587 (7833), 281-284, 2020
1412020
Identification of chemicals that mimic transcriptional changes associated with autism, brain aging and neurodegeneration
BL Pearson, JM Simon, ES McCoy, G Salazar, G Fragola, MJ Zylka
Nature communications 7 (1), 11173, 2016
1372016
Gene length matters in neurons
MJ Zylka, JM Simon, BD Philpot
Neuron 86 (2), 353-355, 2015
1352015
Tumor-specific retargeting of an oncogenic transcription factor chimera results in dysregulation of chromatin and transcription
M Patel, JM Simon, MD Iglesia, SB Wu, AW McFadden, JD Lieb, IJ Davis
Genome research 22 (2), 259-270, 2012
1302012
Molecular classification of Crohn's disease reveals two clinically relevant subtypes
M Weiser, JM Simon, B Kochar, A Tovar, JW Israel, A Robinson, ...
Gut, gutjnl-2016-312518, 2016
1292016
A myelin-related transcriptomic profile is shared by Pitt–Hopkins syndrome models and human autism spectrum disorder
BDN Phan, JF Bohlen, BA Davis, Z Ye, HY Chen, B Mayfield, SR Sripathy, ...
Nature neuroscience 23 (3), 375-385, 2020
1142020
scRNA-seq in medulloblastoma shows cellular heterogeneity and lineage expansion support resistance to SHH inhibitor therapy
JK Ocasio, B Babcock, D Malawsky, SJ Weir, L Loo, JM Simon, MJ Zylka, ...
Nature communications 10 (1), 5829, 2019
1062019
Spinal macrophages resolve nociceptive hypersensitivity after peripheral injury
JK Niehaus, B Taylor-Blake, L Loo, JM Simon, MJ Zylka
Neuron 109 (8), 1274-1282. e6, 2021
972021
Primary Cilia Signaling Promotes Axonal Tract Development and Is Disrupted in Joubert Syndrome-Related Disorders Models
J Guo, JM Otis, SK Suciu, C Catalano, L Xing, S Constable, D Wachten, ...
Developmental Cell 51 (6), 759-774. e5, 2019
962019
Combination therapy with potent PI3K and MAPK inhibitors overcomes adaptive kinome resistance to single agents in preclinical models of glioblastoma
RS McNeill, DA Canoutas, TJ Stuhlmiller, HD Dhruv, DM Irvin, RE Bash, ...
Neuro-oncology 19 (11), 1469-1480, 2017
652017
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