| The FDA-approved drug ivermectin inhibits the replication of SARS-CoV-2 in vitro L Caly, JD Druce, MG Catton, DA Jans, KM Wagstaff Antiviral research 178, 104787, 2020 | 2778 | 2020 |
| Ivermectin is a specific inhibitor of importin α/β-mediated nuclear import able to inhibit replication of HIV-1 and dengue virus KM Wagstaff, H Sivakumaran, SM Heaton, D Harrich, DA Jans Biochemical Journal 443 (3), 851-856, 2012 | 867 | 2012 |
| Towards safe, non-viral therapeutic gene expression in humans DJ Glover, HJ Lipps, DA Jans Nature Reviews Genetics 6 (4), 299-310, 2005 | 842 | 2005 |
| Nuclear targeting signal recognition: a key control point in nuclear transport? DA Jans, CY Xiao, MHC Lam Bioessays 22 (6), 532-544, 2000 | 710 | 2000 |
| Regulation of protein transport to the nucleus: central role of phosphorylation DA Jans, S Hubner Physiological reviews 76 (3), 651-685, 1996 | 567 | 1996 |
| The rate of nuclear cytoplasmic protein transport is determined by the casein kinase II site flanking the nuclear localization sequence of the SV40 T‐antigen. HP Rihs, DA Jans, H Fan, R Peters The EMBO Journal 10 (3), 633-639, 1991 | 456 | 1991 |
| Regulation of nuclear transport: central role in development and transformation? IKH Poon, DA Jans Traffic 6 (3), 173-186, 2005 | 448 | 2005 |
| The broad spectrum antiviral ivermectin targets the host nuclear transport importin α/β1 heterodimer SNY Yang, SC Atkinson, C Wang, A Lee, MA Bogoyevitch, NA Borg, ... Antiviral research 177, 104760, 2020 | 436 | 2020 |
| Nuclear localization of dengue virus (DENV) 1–4 non-structural protein 5; protection against all 4 DENV serotypes by the inhibitor Ivermectin MYF Tay, JE Fraser, WKK Chan, NJ Moreland, AP Rathore, C Wang, ... Antiviral research 99 (3), 301-306, 2013 | 377 | 2013 |
| An efficient system for high‐level expression and easy purification of authentic recombinant proteins AM Catanzariti, TA Soboleva, DA Jans, PG Board, RT Baker Protein Science 13 (5), 1331-1339, 2004 | 364 | 2004 |
| Nuclear import of insulin-like growth factor-binding protein-3 and-5 is mediated by the importin β subunit LJ Schedlich, SL Le Page, SM Firth, LJ Briggs, DA Jans, RC Baxter Journal of Biological Chemistry 275 (31), 23462-23470, 2000 | 360 | 2000 |
| The protein kinase CK2 site (Ser111/112) enhances recognition of the simian virus 40 large T-antigen nuclear localization sequence by importin S Hübner, CY Xiao, DA Jans Journal of Biological Chemistry 272 (27), 17191-17195, 1997 | 311 | 1997 |
| Targeted delivery to the nucleus CW Pouton, KM Wagstaff, DM Roth, GW Moseley, DA Jans Advanced drug delivery reviews 59 (8), 698-717, 2007 | 307 | 2007 |
| Cytosolic delivery of granzyme B by bacterial toxins: evidence that endosomal disruption, in addition to transmembrane pore formation, is an important function of perforin KA Browne, E Blink, VR Sutton, CJ Froelich, DA Jans, JA Trapani Molecular and cellular biology 19 (12), 8604-8615, 1999 | 283 | 1999 |
| The Type III Effectors NleE and NleB from Enteropathogenic E. coli and OspZ from Shigella Block Nuclear Translocation of NF-κB p65 HJ Newton, JS Pearson, L Badea, M Kelly, M Lucas, G Holloway, ... PLoS pathogens 6 (5), e1000898, 2010 | 274 | 2010 |
| p34cdc2-mediated phosphorylation at T124 inhibits nuclear import of SV-40 T antigen proteins. DA Jans, MJ Ackermann, JR Bischoff, DH Beach, R Peters Journal of Cell Biology 115 (5), 1203-1212, 1991 | 269 | 1991 |
| Importin β recognizes parathyroid hormone-related protein with high affinity and mediates its nuclear import in the absence of importin α MHC Lam, LJ Briggs, W Hu, TJ Martin, MT Gillespie, DA Jans Journal of Biological Chemistry 274 (11), 7391-7398, 1999 | 264 | 1999 |
| Structural basis for the specificity of bipartite nuclear localization sequence binding by importin-α MRM Fontes, T Teh, D Jans, RI Brinkworth, B Kobe Journal of Biological Chemistry 278 (30), 27981-27987, 2003 | 252 | 2003 |
| Targeted intracellular delivery of photosensitizers to enhance photodynamic efficiency AA Rosenkranz, DA Jans, AS Sobolev Immunology and cell biology 78 (4), 452-464, 2000 | 249 | 2000 |
| Influenza A viruses escape from MxA restriction at the expense of efficient nuclear vRNP import V Götz, L Magar, D Dornfeld, S Giese, A Pohlmann, D Höper, BW Kong, ... Scientific reports 6 (1), 23138, 2016 | 243 | 2016 |
