Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation HD Lewis, J Liddle, JE Coote, SJ Atkinson, MD Barker, BD Bax, KL Bicker, ... Nature chemical biology 11 (3), 189, 2015 | 724 | 2015 |
Activation of PAD4 in NET formation A Rohrbach, D Slade, P Thompson, K Mowen Frontiers in immunology 3, 360, 2012 | 400 | 2012 |
Fusobacterium nucleatum host-cell binding and invasion induces IL-8 and CXCL1 secretion that drives colorectal cancer cell migration DJS MA Casasanta, CC Yoo, B Udayasuryan, BE Sanders, A Umaña, Y Zhang, H ... Science Signaling 13 (641), 2020 | 255 | 2020 |
Peptidylarginine deiminase 2-catalyzed histone H3 arginine 26 citrullination facilitates estrogen receptor α target gene activation X Zhang, M Bolt, MJ Guertin, W Chen, S Zhang, BD Cherrington, DJ Slade, ... Proceedings of the National Academy of Sciences 109 (33), 13331-13336, 2012 | 233 | 2012 |
The Cancer Microbiome: Distinguishing Direct and Indirect Effects Requires a Systemic View JB Xavier, VB Young, J Skufca, F Ginty, T Testerman, AT Pearson, ... Trends in Cancer, 2020 | 209 | 2020 |
The gut microbial metabolite formate exacerbates colorectal cancer progression D Ternes, M Tsenkova, VI Pozdeev, M Meyers, E Koncina, S Atatri, ... Nature Metabolism, 1-18, 2022 | 179 | 2022 |
Protein arginine deiminase 2 binds calcium in an ordered fashion: implications for inhibitor design DJ Slade, P Fang, CJ Dreyton, Y Zhang, J Fuhrmann, D Rempel, BD Bax, ... ACS chemical biology 10 (4), 1043-1053, 2015 | 123 | 2015 |
Crystal structure of the MACPF domain of human complement protein C8α in complex with the C8γ subunit DJ Slade, LL Lovelace, M Chruszcz, W Minor, L Lebioda, JM Sodetz Journal of molecular biology 379 (2), 331-342, 2008 | 100 | 2008 |
Chemical proteomic platform to identify citrullinated proteins DM Lewallen, KL Bicker, V Subramanian, KW Clancy, DJ Slade, J Martell, ... ACS chemical biology 10 (11), 2520-2528, 2015 | 91 | 2015 |
Chemical and biological methods to detect post‐translational modifications of arginine DJ Slade, V Subramanian, J Fuhrmann, PR Thompson Biopolymers 101 (2), 133-143, 2014 | 79 | 2014 |
Fusobacterium nucleatum induces proliferation and migration in pancreatic cancer cells through host autocrine and paracrine signaling B Udayasuryan, RN Ahmad, TTD Nguyen, A Umaña, LD Monét Roberts, ... Science Signaling 15 (756), eabn4948, 2022 | 77 | 2022 |
Utilizing Whole Fusobacterium Genomes To Identify, Correct, and Characterize Potential Virulence Protein Families A Umaña, BE Sanders, CC Yoo, MA Casasanta, B Udayasuryan, ... Journal of bacteriology 201 (23), 2019 | 58* | 2019 |
A chemical and biological toolbox for Type Vd secretion: Characterization of the phospholipase A1 autotransporter FplA from Fusobacterium nucleatum MA Casasanta, CC Yoo, HB Smith, AJ Duncan, K Cochrane, AC Varano, ... Journal of Biological Chemistry 292 (49), 20240-20254, 2017 | 48 | 2017 |
Biological Studies and Target Engagement of the 2-C-Methyl-d-Erythritol 4-Phosphate Cytidylyltransferase (IspD)-Targeting Antimalarial Agent (1 R, 3 S)-MMV008138 and Analogs M Ghavami, EF Merino, ZK Yao, R Elahi, ME Simpson, ... ACS infectious diseases 4 (4), 549-559, 2017 | 46 | 2017 |
Calcium Regulates the Nuclear Localization of Protein Arginine Deiminase 2 L Zheng, M Nagar, AJ Maurais, DJ Slade, SS Parelkar, SA Coonrod, ... Biochemistry, 2019 | 43 | 2019 |
Pluripotency: citrullination unravels stem cells DJ Slade, V Subramanian, PR Thompson Nature chemical biology 10 (5), 327, 2014 | 39 | 2014 |
Comparative Analysis of Colon Cancer-Derived Fusobacterium nucleatum Subspecies: Inflammation and Colon Tumorigenesis in Murine Models J Queen, JC Domingue, JR White, C Stevens, B Udayasuryan, ... mBio 13 (1), e02991-21, 2022 | 37 | 2022 |
Fusobacterium nucleatum CbpF mediates inhibition of T cell function through CEACAM1 activation J Galaski, A Shhadeh, A Umaña, CC Yoo, L Arpinati, B Isaacson, ... Frontiers in Cellular and Infection Microbiology 11, 484, 2021 | 34 | 2021 |
Functional studies of the MACPF domain of human complement protein C8α reveal sites for simultaneous binding of C8β, C8γ, and C9 DJ Slade, B Chiswell, JM Sodetz Biochemistry 45 (16), 5290-5296, 2006 | 32 | 2006 |
FusoPortal: an Interactive Repository of Hybrid MinIONSequenced Fusobacterium Genomes Improves Gene Identification and Characterization BE Sanders, A Umana, A Lemkul, Justin, DJ Slade mSphere 3 (4), 2018 | 29 | 2018 |