Design, synthesis and screening of 1, 2, 4-triazinone derivatives as potential antitumor agents with apoptosis inducing activity on MCF-7 breast cancer cell line I Zaki, MK Abdelhameid, IM El-Deen, AHAA Wahab, AM Ashmawy, ... European Journal of Medicinal Chemistry 156, 563-579, 2018 | 64 | 2018 |
Synthesis and biological evaluation of new pyrazolone–pyridazine conjugates as anti-inflammatory and analgesic agents NA Khalil, EM Ahmed, KO Mohamed, YM Nissan, SAB Zaitone Bioorganic & medicinal chemistry 22 (7), 2080-2089, 2014 | 59 | 2014 |
Synthesis of Novel Substituted Thiourea and Benzimidazole Derivatives Containing a Pyrazolone Ring as Anti-Inflammatory Agents KOMHBEN Ashraf A. Moneer chemical biology and drug design 87 (5), 784-793, 2015 | 45* | 2015 |
Synthesis, Molecular Docking, and Biological Evaluation of Some Novel Hydrazones and Pyrazole Derivatives as Anti-inflammatory Agents KOMYM Nissan chemical biology and drug design 84 (4), 473-488, 2014 | 45 | 2014 |
Design, synthesis and biological evaluation of some novel sulfonamide derivatives as apoptosis inducers KO Mohamed, YM Nissan, AA El-Malah, WA Ahmed, DM Ibrahim, ... European journal of medicinal chemistry 135, 424-433, 2017 | 40 | 2017 |
Synthesis of novel 1, 3, 4-thiadiazole analogues with expected anticancer activity DEA Rahman, KO Mohamed Der Pharma Chemica 6 (1), 323-335, 2014 | 35 | 2014 |
Design, synthesis, and cytotoxic screening of novel azole derivatives on hepatocellular carcinoma (HepG2 Cells) MK Abdelhameid, I Zaki, MR Mohammed, KO Mohamed Bioorganic chemistry 101, 103995, 2020 | 31 | 2020 |
Evaluation of N-phenyl-2-aminothiazoles for treatment of multi-drug resistant and intracellular Staphylococcus aureus infections IG Shahin, NS Abutaleb, M Alhashimi, AE Kassab, KO Mohamed, ... European Journal of Medicinal Chemistry 202, 112497, 2020 | 28 | 2020 |
Synthesis and biological evaluation of pyrazolone analogues as potential anti‐inflammatory agents targeting cyclooxygenases and 5‐lipoxygenase MA Shabaan, AM Kamal, SI Faggal, AE Elsahar, KO Mohamed Archiv der Pharmazie 353 (4), 1900308, 2020 | 26 | 2020 |
Synthesis and biological evaluation of halogenated phenoxychalcones and their corresponding pyrazolines as cytotoxic agents in human breast cancer PA Halim, RA Hassan, KO Mohamed, SO Hassanin, MG Khalil, AM Abdou, ... Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 189-201, 2022 | 24 | 2022 |
Design, synthesis, and biological evaluation of new pyrazoloquinazoline derivatives as dual COX‐2/5‐LOX inhibitors MA Shaaban, AM Kamal, SI Faggal, NA Farag, NM Aborehab, AE Elsahar, ... Archiv der Pharmazie 353 (11), 2000027, 2020 | 24 | 2020 |
A new class of diamide scaffold: Design, synthesis and biological evaluation as potent antimitotic agents, tubulin polymerization inhibition and apoptosis inducing activity studies KO Mohamed, I Zaki, IM El-Deen, MK Abdelhameid Bioorganic Chemistry 84, 399-409, 2019 | 23 | 2019 |
Design, synthesis and assessment of new series of quinazolinone derivatives as EGFR inhibitors along with their cytotoxic evaluation against MCF7 and A549 cancer cell lines MW Aziz, AM Kamal, KO Mohamed, AA Elgendy Bioorganic & medicinal chemistry letters 41, 127987, 2021 | 22 | 2021 |
Synthesis of new nicotinic acid derivatives and their evaluation as analgesic and anti-inflammatory agents NA Khalil, EM Ahmed, KO Mohamed, SAB Zaitone Chemical and Pharmaceutical Bulletin 61 (9), 933-940, 2013 | 22 | 2013 |
Design and synthesis of pyrazolo [3, 4-d] pyrimidinone derivatives: Discovery of selective phosphodiesterase-5 inhibitors MA Shaaban, YAMM Elshaier, AH Hammad, NA Farag, HH Haredy, ... Bioorganic & Medicinal Chemistry Letters 30 (16), 127337, 2020 | 19 | 2020 |
New benzenesulfonamide scaffold-based cytotoxic agents: Design, synthesis, cell viability, apoptotic activity and radioactive tracing studies YM Nissan, KO Mohamed, WA Ahmed, DM Ibrahim, MM Sharaky, ... Bioorganic Chemistry 96, 103577, 2020 | 19 | 2020 |
3-[(6-Arylamino) pyridazinylamino] benzoic acids: design, synthesis and in vitro evaluation of anticancer activity KAM Abouzid, NA Khalil, EM Ahmed, KO Mohamed Archives of pharmacal research 36, 41-50, 2013 | 17 | 2013 |
Development of new donepezil analogs: synthesis, biological screening and in silico study rational Z Mahmoud, HS Sayed, LW Mohamed, KO Mohamed Medicinal Chemistry Research 31 (10), 1754-1770, 2022 | 15 | 2022 |
Design, synthesis and cytotoxicity screening of new thiazole derivatives as potential anticancer agents through VEGFR-2 inhibition T Al-Warhi, M Abualnaja, OA Abu Ali, NM Alyamani, FG Elsaid, AA Shati, ... Symmetry 14 (9), 1814, 2022 | 12 | 2022 |
Design, synthesis, and antipoliferative activities of novel substituted imidazole-thione linked benzotriazole derivatives AN Khayyat, KO Mohamed, AM Malebari, A El-Malah Molecules 26 (19), 5983, 2021 | 11 | 2021 |